Occam's Toothbrush

NEW - Trump has signed off on a plan to fire his FDA Commissioner, Dr. Marty Makary. gift link below

Well over a billion dollars raised for $ORKA’s decade+ late psoriasis me-too drugs. I can’t emphasize enough the fact there are ZERO psoriasis patients under my care that we cannot control with existing options. 1-2 shots per year instead of 4 is not meaningful innovation, period. Over a billion dollars going to this instead of other medical innovation. Psoriasis is just about the *only* condition in my field where we flat out don’t need something new, and these funds are just stuffing cash down ORKA’s throat to get their performance locks the easy way instead of investing somewhere that could actually benefit someone. As long as nobody sells for a while they’ll all make money, even if these stupid companies can’t get an exit in the long run. The investing system *should* be set up such that it doesn’t reward this nonsense - so far it isn’t. I know there are a lot of smart people involved in this who I otherwise like and respect, but I won’t mince words (hopefully they’ll at least respect me for that): This entire YTE situation is a pathetic use of the incentive system that’s supposed to ultimately help patients by creating medical innovation. As investors we are nothing but parasites if we aren’t taking risks to profit off of innovation and financial engineering our way to success instead. The only way this YTE situation works in the long run from these current valuations is if they are able to exploit a completely broken payor system by forcing doctors to abandon perfectly good generic drugs that the system could cheaply afford. I think this whole thing is gross.