You Chen, PhD, FAMIA

Vanderbilt is using AI to tackle obesity care. The $1M project will dig into why patients stop treatment & create new tools to help them stay on track. #AIinHealthcare #HealthTech news.vumc.org/2025/09/17/van…

Genes matter for side effects. Analyzing 250k genomes at VUMC, we found CYP2C19 & CYP3A4 help explain omeprazole-related myopathy. Details in our new paper: accpjournals.onlinelibrary.wiley.com/doi/10.1002/ph… #precisionmedicine #pharmacogenomics #xingyiguo #PharmacoJournal

Excited to share our new Perspective in npj Health Systems. Integrating clinician-EHR interaction data with patient data opens a powerful, underutilized avenue for building AI that is both context-aware and care-centered. Amazing team @ZXinmeng @TKannampallil @j_r_a_m @ohpenlab

@HeadacheJournal @mmogos2 "your paper on February 17 has been viewed over 2724 times and reposted 5 times. Your paper has over 400 full-text views since it was published online." from Headache Editorial Team. @vumcdbmi @VUBasicSciences @VUMCResearch

Open Access: A retrospective study finds that #propranolol use in women who have #migraine without aura was associated with a reduction in ischemic #stroke risk …adachejournal.onlinelibrary.wiley.com/doi/full/10.11… @mmogos2 et al

Weight-loss surgery associated with reduced dementia news.vumc.org/2025/02/17/wei… @vumcdbmi @WorldObesity @alzassociation @DIkramuddin @YuDanxia_Epi

Excited to share our study in Annals of Surgery Open: Bariatric Surgery is linked to a lower risk of mild cognitive impairment and Alzheimer’s/dementias. @vumcdbmi @VUMCSurgery @VUMC_Insights @ZXinmeng @YuDanxia_Epi @DIkramuddin @RuiZhang1229 journals.lww.com/aosopen/fullte…

One of our recent drug interaction studies was highlighted by All of Us: "Checking Medicine Safety with All of Us". They have both English and Spanish versions 👍. @vumcdbmi allofus.nih.gov/news-events/re…

@ZXinmeng @vumcdbmi @VUMCSurgery A great and timely study to show the big potentiality of AI and digital health in improving patient outcomes!

New research alert 📣 Excited to share our latest study on the association between patient portal engagement and weight loss after #BariatricSurgery. jmir.org/2024/1/e56573. @ohpenlab @vumcdbmi @VUMCSurgery 1/3

Excited to share our new paper on AI’s role in modern care coordination, exploring digital information ecosystems and patient care pathways. Grateful to @bradmalin , @culehmann for their support. Read it here: jmir.org/2024/1/e60258?… out this fascinating article by @jmirpub!

Can we extract unrecognized severe adverse reactions with known pharmacokinetic mechanisms from biomedical literature using NLP tools and validate the signals through real-world data? See our paper accepted to #CPTJournal. ascpt.onlinelibrary.wiley.com/doi/10.1002/cp… #ASCPTJournalFamilyDiscovering

🚨 New preprint: Greater #patientportal engagement was associated with improved postoperative weight loss in #BariatricSurgery patients. @VUMCSurgery @vumcdbmi @kaidikangkk @yanchao0222 @trentrosenbloom @ohpenlab @metabolic_knife @VandyAtVandy @YuDanxia_Epi #PatientEngagement

Thrilled to share that I've been promoted to Associate Professor with tenure! A heartfelt thank you to my students, colleagues, and mentors who've supported me on this journey. Here's to continuing to explore, and make an impact! @vumcdbmi @bradmalin @trentrosenbloom @embimd

An in-depth network analysis uncovers the dynamic progression of drug-drug interaction studies spanning the previous 60 years. Detailed insights can be found frontiersin.org/articles/10.33…

Discover how #HumanCenteredAI can help tackle biases & promote equitable care in healthcare systems. @bradmalin @genomemom @laurielovett jmir.org/2023/1/e43251

Inbasket unbearable? Involuntary, never-ending, after-hours 2nd job? Shanafelt, Ripp & I suggest health systems: 1. Measure IB volume 2. Turn off low-value notifications 3. Delegate to upskilled team 4. Pay for the work 5. Research safety & Q of IB care link.springer.com/article/10.100…

@siru_liu @NLM_NIH @adamatw @allisonbmccoy @deansittig @JoshPetersonMD @VUMC_VCLIC @vumcdbmi @EFSInsideScoop Congratulations!

I feel honored to get a K99/R00 grant from @NLM_NIH to continue my research in optimizing CDS using explainable AI (my 1st NIH submission). Thank you to my mentors: @adamatw @allisonbmccoy @deansittig @JoshPetersonMD and Thomas Lasko! @VUMC_VCLIC @vumcdbmi @EFSInsideScoop

@feiwang03 I thought it was several years ago. :-)

Finally, officially tenured…

While using COVID-19 drugs, they may have reactions with other drugs. This data-driven discovery study would provide some hypotheses on DDIs.⁦@vumcdbmi⁩ Eugene Jeong, ⁦@scottnelsonrx⁩ ⁦⁦⁦@bradmalin⁩ Lang Li, and Yu Su. frontiersin.org/articles/10.33…