Our new study! Bile acids are natural ligands for the epithelial sodium channel. Big thanks to the Pochynyuk and Lei groups for their help! physoc.onlinelibrary.wiley.com/doi/10.1113/JP…
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Ossama Kashlan
19 posts
Ossama Kashlan
@okashlan
Scientist at the University of Pittsburgh. Views are my own.
Pittsburgh, Pennsylvania Katılım Şubat 2009
83 Takip Edilen37 Takipçiler
Ossama Kashlan retweetledi
Kidney-Specific KO of the Circadian Clock Protein PER1 Alters Renal Sodium Handling, Aldosterone Levels, and Kidney/Adrenal Gene Expression - new in @AJPRenal
ow.ly/xoLz50HQHZG
#homeostasis #articlesinpress
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Ossama Kashlan retweetledi
‘I Want To Be In The Olympics Someday,’ Says Delusional Kindergartner Already 4 Years Behind In Elite Training bit.ly/3AXD8IL
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Control over the activation of the #ENaC sodium channel through the addition of cleavage sites happened during the vertebrate land invasion. bit.ly/3K3d1Eb
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Adaptations to breathe air and conserve salt and water gave aquatic vertebrates access to new resources on land. These required molecular changes.
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Excited to share our latest work in @eLife with @NathanClark111 on the evolution of a sodium channel crucial to kidney and lung function. elifesciences.org/articles/75796
Nathan Clark nclark.bsky.social@NathanClark111
It was a delight to be part of this study w/ @okashlan on the evolution of kidney and lung ion homeostasis during the transition of vertebrates from ocean to dry land. doi.org/10.7554/eLife.…
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Thank you for letting me know. It’s working, Walmart just has the MOST people and the least barrier to entry (no forced bundles). So it’s the toughest.
PattiCakes@pattimidler
I got one! Thank you @mattswider ! Refreshing works!
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Ossama Kashlan retweetledi
If you don’t want to see big roly-poly pandas rolling down hills in a rare DC snowstorm then LOOK AWAY
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Really enjoyed @LabZhu Bokai Zhu's talk today about the 12-hour circatidal biological clock. Who knew we shared so much with clams? journals.plos.org/plosbiology/ar…
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@BMBlobner 99% may be high. Futures in Teds Cruz, London/Vancouver real estate, and the like would look brighter.
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I think we need a 99% tax rate for all earnings over $1 billion and a minimum wage that people can live off of.
❂🔻@BlFLEXUAL
yall when yall when fast Jeff Bezos food workers makes $13 get paid a billion dollars barely liveable in one day wage
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👩🔬🔬I have just accepted the Associate Professor of Physiology position at the @MCG_AUG in Augusta, GA @AUG_University, where my lab will move in summer. I look forward to working with all the fabulous people there! I will miss my colleagues at @musc_nephrology #physiology
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@baseballot Former PA House representative Rick Saccone @realRickSaccone was there... faced @ConorLambPA in 2018 special election for PA18.
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Looks like I missed some (many of these people say they left when things got violent, though):
-AK state Rep. David Eastman
-AZ state Rep. Mark Finchem
-Incoming NV state Assemb. Annie Black
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Up to six state legislators I'm aware of who were in Wednesday's mob:
-MI state Rep. Matt Maddock
-MO state Rep. Justin Hill
-PA state Sen. Doug Mastriano
-TN state Rep. Terri Lynn Weaver
-VA state Sen. Amanda Chase
-WV state Del. Derrick Evans
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@ChristosArgyrop Is 4k already baked in? The hospitalizations are still rising rapidly.
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@seffikogen @mattyglesias @mattyglesias reminds me of Michael Kinsley. His values and perspective are clearly center-left, and yet he's open to persuasion and heterodox views.
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For some reason I never thought @mattyglesias was for me. I didn't read Vox much, and didn't seek out his opinion, until just a few months ago. Now, I've subscribed to his Substack and holy HECK are his posts absolute fire. Incredible thinking, great writing, VERY worth reading.
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@jmhorp True for new cases. For total cases you need to compare the areas under each curve.
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The EU has now caught up to the US in confirmed COVID cases (yes, it's adjusted for population)
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Ossama Kashlan retweetledi
Nobel Prize in Medicine to the 3 scientists that discovered HEPATITIS C. A great recognition to the greatest achievement of hepatology. Now it is time to erradicate it !!
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Ossama Kashlan retweetledi
NEWS: PA Sen Pat Toomey will not run for governor or reelection in 2022. Announcement expected Monday.
He'll serve out his current senate term.
w/ @wbender99
fusion.inquirer.com/politics/penns…
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Genetic consequence to the tragedy in Syria: wired.com/2015/04/syrian…
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