PathInsights MD ⚕️

❗Appendix LAMN pitfall : to check if a mucin deposit is real (and not place there during the handling of the specimen) have in mind that a true accumulation of mucin is associated with neovascularization #GIPath #Pathology #PathX #PathResident #surgpath #surgicalpathology #PathTwitter #appendixlamn

Solitary intrapulmonary fibrous tumor with an adenofibromatous pattern: A case report elsevier.es/es-revista-rev… ————— @smlungpathguy @Sara_Jiang @JMGardnerMD @lara_pijuan

Case of the day : M, 68, thigh mass with a nasty rhabdoid morphology. In waiting for the IHC results, first differentials would include melanoma with rhabdomyosarcomatous differentiation or an anaplastic/pleomorphic rhabdomyosarcoma. Opinions? #softtissue #Path #PathX #PathResident #pathology

#GUpath prostate laser enucleation for BPH: worrisome luminal mucin? nah...just #beautyinb9 basal cell hyperplasia (can occasionally have mucin🚨+nucleoli)

You can see that the LVI (tumor embolus) is also mimicking a DCIS growth pattern!

!! Extremely rare pitfall : Pseudo DCIS ("DCIS-like") invasive growth pattern seen in an invasive breast carcinoma, NST (invasive ductal carcinoma), grade 2. * last pic shows associated low-grade cribriform DCIS for comparison ** bonus in comments #breastpath #PathX #PathResident #pathology

Typical example of an intravascular papillary endothelial hyperplasia (IPEH), also known as Masson tumor. ~ Benign intravascular endothelial proliferation composed of numerous papillary structures within vascular spaces ~ #softtissuepath #vasculartumors #pathX #PathResident #pathology

Malignant lymphoma, large B cell, diffuse (DLBCL) involving the colonic wall in a 60 years old female. #hempath #pathX #PathResident #surgicalpathology #pathology #surgpath

Organ? Dx? #PathX #PathTwitter

Plasmacytoid urothelial carcinoma 🫒

before making Dx of "idiopathic granulomatous orchitis", be sure to rule out: germ cell tumor (usually seminoma), lymphoma (often Hodgkin), sarcoid (Dx of exclusion), and infection (TB, or like in this case of cocci) #GUpath Dx: granulomatous orchitis secondary to coccidiosis

"I am a retroperitoneal tumor with uncertain origin occurring in a middle-aged man and morphologically looking like an anaplastic large cell lymphoma/ undifferentiated sarcoma. My IHC profile shows positivity for SALL4, OCT3/4, PLAP & D2-40, also excluding a liposarcoma. Who am I? Well, I'm not a very common seminoma." #uropathology #PathX #PathResident

~ Kaposi sarcoma ~ #softtissuepath #pathX #PathResident #surgpath #surgicalpathology #pathology

Typical hibernoma 👉Rare, benign, adipocytic tumor composed of variable proportions of brown fat cells admixed with white adipose tissue #softtissuepath #pathology #pathX #pathresident #surgpath #surgicalpathology #softtissuepathology

Ovary, Disgerminoma 👉 Most common malignant ovarian germ cell tumor 👉 female counterpart to testicular seminoma 👉 Histologic hallmarks : 🔹Characteristic appearance of nests of large, uniform polygonal cells with distinct cell membranes imparting an alveolar pattern 🔹Areas of dystrophic calcification ( ❗DDX : Gonadoblastoma) 🔹Inflammation in fibrous septae containing lymphohistiocytic infiltrates (❗helps distinguishing it from embryonal carcinoma) 🔹Nuclear markers positivity: OCT3/4 & SALL4 #gynecopath #PathX #PathResident #Pathology #surgpath #surgicalpathology #PathTwitter