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70M with parotid mass. What is your diagnosis? #oralpath #oralpathology #pathology #pathologists #pathTwitter #HeadNeckPathol #HeadandNeckPath #ENTPath #PathologyTweet

Bone lesions ⚠️⚠️⚠️ Quick reminder ‼️

Biphasic synovial sarcomas have: 1) An epithelioid component forming cohesive structures, often tubules 2) A spindle cell component forming fascicles of monotonous cells with very high N:C ratios +S18-SSX fusion-specific antibody (better than TLE1) WSI: pathlibrary.com/slidebox/?case…

PTC - Tall cell variant

19 yo F with arm nodule. One of my favorite cases! Answer ✅ youtube.com/watch?v=obIibd… Digital slide: kikoxp.com/posts/21601 Another case: kikoxp.com/posts/17751 #pathology #pathologists #pathTwitter #dermpath #dermatology #bstpath #dermtwitter

The next issue of @ACP_Pathologist news is about teachers and trainers. Tell us your stories!

Rectal muciphages; useful to identify the distal biopsy in an unlabelled colonic series. #Pathologists dont confuse them for sampling of a xanthoma! #GIPath

This spectacular metastatic dedifferentiated gastrointestinal stromal tumor to the liver mimics hepatocellular carcinoma.

"Someone has a case of The Mondays." - Amoebas, probably.

The beauty of intestinal villi never ceases to amaze me 🤩

Neck lymph node, older patient #ENTpath #BSTpath #Hemepath #Endopath #Dermpath #Pathtwitter #Pathresidents

The NHS need to create a national, cloud based digital pathology system to allow outsourcing and expert second opinions, preventing local silos that would otherwise require already digitised glass slides being sent away. Read more at the following link... pathkids.com/wp/2025/05/09/…

Excision of lateral tongue for high grade dysplasia but showing some rarely seen and beautiful microanatomical variants. Lateral lingual tonsillar tissue, taste buds lining clefts of foliate papillae and subgemmal neurogenous plaque. #ENTpath @sakhurram @ENTpathology

Micropapillary urothelial carcinoma presenting as a rectal mass!

Resection of a parotid gland mass revealing what type of tumor? Answer: buff.ly/fOvoSPB #PathArt #PathTwitter #MedTwitter buff.ly/hpglxhh

Random non-polypoid stomach biopsy. History of colonic inflammatory polyps and recent diarrhea/proctitis from Shigella flexneri. All other infectious workup negative.

A nasty met of melanoma in inguinal lymph node. The peritheliomatous distribution of melanoma cells (most are rhabdoid and plasmacytoid here) can be mistaken as perivascular formations of metastatic germ cell tumors without appropriate history. The patient has primary in big toe.

Salivary gland neuroendocrine carcinoma of small cell (Merkel)-type; CK20 dot-positive. TTF1-, PET scan, skin survey and lack of tumour UV DNA signatures can help exclude spread from far more likely occult thoracic or cutaneous primary journals.lww.com/ajsp/abstract/… @ENTpathology

Molecular Testing Basics explained in 15 minutes (video): youtube.com/watch?v=CetNjr… . A simple explanation of the main types of molecular tests #pathologists use, when we use them, & why. #pathology #pathTwitter #MedTwitter #MedEd #MolPath #dermtwitter #dermpath

Paget’s disease of perianal squamous mucosa associated with a non-invasive prolapsing anorectal adenoma with high grade dysplasia. Like the @LizMontgomeryMD series our case didnt show submucosal invasion, and the Paget cells had a “colorectal” (CK7- CK20+ CDX2+) Immunophenotype.