Patrick Turley

Perhaps this is a reason for more investigator-based grant mechanisms where they discuss general research agendas rather than concrete plans for specific projects.

But with the speed that methods can be developed, tested, and applied using things like Claude Code, 8 months is way too slow. By the time a reviewer sees a proposal, the work will probably have been done ages ago!

One concern that I don't see people talking about much is how AI will affect the rhythm of grant applications for stat gen work.

Disclaimer: I don't entirely vouch for the validity of these numbers, which were generated with 10 minutes of vibe coding with Claude Code and 5 minutes of spot checking to make sure it was all sensible. And lots of limitations to my design. Just thought it was interesting

There is also a drop in active projects in 2025. This could be because people have stopped using the RAP or because more people are piling onto a smaller number of applications.

Over the course of 2025, UKB researchers were forced to move all of their data analysis to the cloud rather than working with local copies. What was the effect of this move on scientific output? Here is a simple first pass at answering that question.

@SashaGusevPosts @AlexTISYoung Very strange. Do you think the person who posted it meant "unbiased by researcher priors" as opposed to "statistically unbiased"?

@AlexTISYoung I saw this tweet and thought they were covering a new method

'Powerful' yes, 'unbiased' no.

I first read the first line as "PNAS is really bad for babies," and thought "Wow! I mean, every journal has its problems, but this seems a little harsh, no?"

extra! extra! ter.li/JuliaB

@UpdatedPriors Apparently not well enough to have any idea what he was saying to me!

My claim to fame for the Nobel Prize this year is that I played Aghion in the Econ Department holiday party years ago, and my impression was so good, he tried talking to me in French afterwards.

Here is our new preprint (medrxiv.org/cgi/content/sh…). We report heritability estimates for multiple traits using a within-family design in 500,000 sibling pairs of diverse ancestries! Fantastic collaboration with @23andMeResearch! Thanks to their participants and research team.

I’m excited to participate in Mass General’s 5th annual Conference on Precision Psychiatry, which will be held virtually on Sept. 25–26. It’s free for trainees and learners and there is a discount code below for everyone else.

@AlexTISYoung Good luck with this round, Alex!

Stage IV cancer is a rollercoaster - cliche but true - where one week you are completely non-functional and another you can hike up a large mountain (Mt Baden Powell, 2870m). I'm back in for chemotherapy infusion 3/4 of this round on Tuesday, which will floor me again for another week and leave me with a horrible skin rash for a month. Then I have radiation to look forward to, then possibly more chemotherapy. You have to take the few moments when you feel OK to live again - you have an acute awareness of the finite supply of such moments.

To reiterate what is in the statement: I was not at all involved in the construction of @herasight's pgs models. My main contribution to Herasight's technology will be detailed in a forthcoming publication, and is only indirectly related to PGS.

A statement from the SSGAC Steering Committee: