/) pablo s.

@TennisCentel Anyone has heard of mikhail youzhny here?

Coco Gauff hits herself hard in the head with the tennis racket after double faulting to lose the set 😳

@aryanistweeting @grok where can I find this article?

wow, this entire paper is such a gem. i read it thrice, skimmed, understanding math, understanding impact. and i just cannot ignore how beautiful and brilliant it is to completely ditch RNNs and LSTMs and rely SOLELY on attention mechanisms. this is pure thinking outside the box. wow wow wow. can't get enough of this. looks like i got a paper for re-reading again and again!

@PaulAustin3w @grok summarize this and tell me why this is important

We can now watch psilocybin grow new brain connections in real time. Not metaphorically. Not "neuroplasticity" as a vague buzzword. Actual, physical structures — dendritic spines — sprouting from cortical neurons within 24 hours of a single dose. A team at Yale used chronic two-photon microscopy to image individual dendritic spines on layer 5 pyramidal neurons in the medial frontal cortex of living mice. Before psilocybin. After psilocybin. Same neurons. Same spines. Day after day. And here's what they found: A single dose of psilocybin produced a ~10% increase in spine density and spine size. New spines began forming within 24 hours. Most of these new connections were still there a month later. That last part matters most. Psilocybin has a half-life of about 3 hours. The molecule is gone by dinner. But the structural changes it triggers persist for at least 34 days (and likely far longer). This is the biological explanation for something clinicians have observed for years: a single psilocybin session producing therapeutic benefits that last months. The drug disappears, but the architecture it built does not. There's a critical mechanistic detail. When researchers pre-treated with ketanserin — a 5-HT2A receptor antagonist — the spine growth was completely blocked. This confirms that structural remodeling depends on activation of the serotonin 2A receptor. The same receptor responsible for the psychedelic experience itself. A 2025 follow-up from the same lab went further. Using rabies tracing to map brain-wide inputs to these new spines, they discovered psilocybin's rewiring is network-specific. It selectively strengthens inputs from perceptual and default mode network regions, the same networks implicated in self-referential processing, rumination, and depression. It doesn't just grow connections randomly. It grows the RIGHT ones. Here's what this means for practitioners: The window after a psychedelic experience isn't just psychological. It's structural. New dendritic spines form and stabilize in the days and weeks following a session. Integration practices — therapy, journaling, somatic work, meditation, breathwork — aren't just processing insights. They may be reinforcing which of these new physical connections survive. You're not just supporting someone's mental model. You're supporting their neural architecture. Think about what that reframes. The integration period isn't a nice-to-have. It's a biological imperative. Those new spines either stabilize into lasting connections or get pruned. The environment, practices, and support during that window may determine which. We're not just learning that psilocybin works. We're watching exactly how it works, at the level of individual synapses. The implications for how we design protocols, structure integration, and time follow-up sessions are enormous. What do you make of this research? Is psilocybin the miracle drug that science makes it out to be?

@Djoko_UTD People will argue over whether it was intentional, but that’s exactly the point. Casper noticed the kid immediately. Little moments like that say a lot.

The moment Casper Ruud entered with the ball kid while the Italian Danderi ignored the kid and was flashing his glasses.. Feel for the kid 💔

@Djoko_UTD @grok what sunglasses are these?

@OpenAIDevs this is the funniest vid i've seen that i have not cracked a giggle to

This guy used AI to put himself in Game of Thrones and fix everything

@steipete what app do u use to communicate with openclaw?

All I want is codex automatically entering /review mode after it's done and just looping until it stops finding booboos. (Yah I'm gonna build that)

@Breaking911 @grok maybe you have access to his mind. Why does this man appear to be walking in the middle of the road? And why does the car look like it’s driving on the side of the road?

😳 Streamer “hmblzayy,” who is walking from Philadelphia to California, was struck by a car in Indiana and transported to the hospital.

@lexrus I use it! I got one for myself and my dad. We love the klacking sounds as we type away

Why would people pay for artificial key sounds? Does anyone need fake mouse click sounds?

@testingcatalog i tried testing it and boom %15 of usage already used. Not very token friendly huh

Anthropic released Claude Design 👀 A new tool to generate UI prototypes, slides, and one-pagers. Claude Design will be gradually rolled out to all paid plans shortly.

Tangerines and @OnyxCoffeeLab for the day

@ivanhzhao Guys, this is an amazing video. Amazing product. I use it everyday but don’t you think there should be a monthly allowance when may 3rd comes around for business users? Instead of having add on credits. I ran 4k credits for March.

The loudest story about AI is a lonely one. One person with an army of chatbots. Other humans are friction. That gets the future wrong. The best things aren’t built alone. In a moment of change, we want to remind the world (and ourselves) what Notion stands for: — Think Together

@markoilico commented!

If you're now designing or redesigning a website, this will help you a lot. I recently curated the best hero sections, footers, social proof and other website parts because I got tired of having 15+ tabs open (even with Mobbin). Giving it away 100% free. Comment on this post, and I'll send a Figma link to your inbox!

@moutet99 vs. @janniksin at @MiamiOpen

@cilic_marin vs. @AlexZverev @MiamiOpen Great atmosphere, good weather, and amazing matches

@WhiteHouse What are you doing?

UNDEFEATED.

@ivanhzhao @akothari Where and when?

Visiting Miami next week with @akothari and looking forward to meet local founders. Who’s free on Tuesday night?