@vitorborin_ Lembra quem nega o aumento de risco com LDL alto.
O que tem de gente negando centenas de evidências e sugerindo que LDL alto é ~~benéfico~~ é um absurdo
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Renato Dumbra
1.1K posts
Renato Dumbra
@renedumbra
Sports nutritionist Unifesp
Sao Paulo, Brazil Katılım Ağustos 2023
248 Takip Edilen32 Takipçiler
Isso ter que ser um hot take (e é) a despeito do imenso corpo de literatura que substancia essa posição é triste.
Poucos assuntos têm uma posição tão contrária a evidências tão inequívocas quanto esse.
Aline Magalhaes@alinefortuna2
Hot take: a decisão de solicitar exames para um paciente não é ato trivial ou isento de risco. A banalização da investigação laboratorial e de imagem causa dano financeiro (sistêmico) e de saúde (individual e populacional) substancial
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@DrJesseMorse @kalos21million @MichaelAlbertMD These studies are mostly measuring fat-free mass, not skeletal muscle directly.
“Lean mass” includes:
water
glycogen
organs
connective tissue
mineral content
the lean component of adipose tissue
and muscle
So saying “30–35% of the weight loss is muscle” is inaccurate
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@kalos21million @MichaelAlbertMD What is the remaining 30%?
Air?
Look into what these 3 studies are actually studying - read about the drugs they were paired with
Then look into the fact that GLPs destroy the stem cells in the skeletal muscle
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Most of what's called "muscle loss" on GLP-1s isn't muscle.
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@sguyenet Added fat CAN be fattening. But added fat is not automatically fattening when it improves satiety, replaces refined carbohydrate, helps adherence, or fits within an eating pattern that naturally lowers body fat levels.
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Added fat is fattening.
It may not be a popular point of view these days, but it remains true.
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@umbertocontiho3 Carlos Miguel nos 90 minutos tá acima, acho q não cabe nem discussão.
Agora pênalti, tb não tem discussão. Hugo é mais consistente nesse quesito.
Considerando que 90 min tem em todo jogo e pênalti quase nunca tem, iria de CM!
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Sem clubismo:
Quem é melhor?
Se puder, justifique.
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Gremio fez uma rachadinha com o Flamengo. Aceitou um suborninho. Quem se vende por isso pode se vender por outros motivos. Quem suborna por isso tb pode subornar para outros fins. É uma questão de índole.
Planeta do Futebol 🌎@futebol_info
🚨 Flamengo repassará R$ 24 milhões ao Grêmio entre 2026 e 2029, após cooperação na disputa por verba dos direitos de TV. O dinheiro faz parte dos R$ 150 milhões que o Rubro-Negro receberá a mais da Libra nesse período. 🗞️ @Estadao | @rodrigocapelo 📸 Divulgação
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@ScottAppliedSci Yeah, he blocked me because I brought up some LDL data and arguments he'd rather ignore.
He's a denialist
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@renedumbra You got Sunny Day to block you?! Respect!! I've had to mute him a while ago for incorrigible dataphobia.
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My single favourite lie about the "carnivore diet" is that it resembles an evolutionary diet for humans and confers health benefits.
Dr Shawn Baker 🥩@SBakerMD
What are you’re favorite lies about a carnivore diet? Some of mine are You’ll definitely get scurvy without fruits and vegetables- proven false by tens of thousands of carnivores not getting scurvy You will lose diversity of you’re microbiome without fiber-proven false by studies that have looked into this You’re brain cannot work without 130 gram of carbohydrate- again proven false by tens of thousands carnivores Meat rots in your colon- actually an idiotic belief promulgated by vegan morons, which is also completely false
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@nicknorwitz It would also be interesting if you posted about how saturated fat harms the liver
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1/6) 2026 research published in Cell Metabolism reveals how fructose harms the liver.
It’s a form of microbiome “alchemy” where microbes convert sugar into a toxic byproduct of alcohol metabolism. Yes, really!
Here’s what you need to know. (Link at the end.)
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@fpenariol @mvicca Cara, é loucura pensar assim. Allan não é lateral nunca
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@renedumbra @mvicca Nada... O Allan marca melhor que o Khelven e joga muito melhor que o Giay... Contra o Santos ele entrou quase como lateral direito...
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Com elenco inteiro do Palmeiras a disposição e em forma, qual seria o seu time titular? Eu:
CM, Giay, Gomez, Murilo, Piquerez, Marlon, Andreas, Paulinho, Arias, Flaco e VR
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@Kansanparantaja @thalesnemo @Backto198433421 @MeTheAngryCat @nicknorwitz By your standard, smoking doesn't "cause" lung cancer.
Not necessary (most smokers never develop it), not sufficient (other factors matter too).
Yet no oncologist debates this.
Because in epidemiology, component causation is enough to establish causality and guide clinical action
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@Kansanparantaja @thalesnemo @Backto198433421 @MeTheAngryCat @nicknorwitz The claim was never "LDL alone causes all CVD."
It's that elevated LDL causally contributes.
That's well established
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I could literally write a book on the number of ways people contort themselves to avoid responding to a legitimate argument 🙄
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Did higher carb intake win the day in the battle of the sub 2-hr marathons? 🧐
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@Kansanparantaja @thalesnemo @Backto198433421 @MeTheAngryCat @nicknorwitz Let’s assume you’re right and the entire scientific community is wrong.
Do you believe that sugar consumption causes diabetes?
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@renedumbra @thalesnemo @Backto198433421 @MeTheAngryCat @nicknorwitz You’re repeating the slogan, not proving the claim.
RCTs do not randomize people to lifelong LDL-C exposure. They test specific LDL-lowering interventions over limited follow-up. MR is not a magic “natural RCT” either. It is an instrumental-variable model. For that model to
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@thalesnemo @Kansanparantaja @Backto198433421 @MeTheAngryCat @nicknorwitz Don't lie: MR studies, and RCT (2 million participants with over 20 million person-years of follow-up) and over 150 000 cdv events demonstrate a dose-dependent log-linear association between the absolute magnitude of exposure of the vasculature to LDL-C and the risk of ASCVD
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@renedumbra @Kansanparantaja @Backto198433421 @MeTheAngryCat @nicknorwitz First link is an ASSOCIATIONAL STUDY which by design cannot prove causation!
2nd link is BROKEN !
Lied too many times by the medical profession writ large ! Any so called evidence is mostly corrupted by corporations selling their snake oils !
My N=1 data trumps official line!
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@PauloJr19701970 @fmac_alexandre @Mr_Hyde1866 Sim. Nesse contexto.
E qualquer coisa fora disso é brincar de roleta russa.
Tenho ctz q você não faria isso, ne?!
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@PauloJr19701970 @fmac_alexandre @Mr_Hyde1866 Sim, quando há hipogonadismo.
E usado em dose de TRT.
Apenas isso!
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@fmac_alexandre @Mr_Hyde1866 MAs dentro disso, engloba
O post é claro: NENHUM estudo prova.
Sim, prova. E há inúmeros outros.
Só pesquisar.
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@thalesnemo @Kansanparantaja @Backto198433421 @MeTheAngryCat @nicknorwitz NNT
Secondary prevention (statin 5y): NNT ~39 for non-fatal MI, NNT ~83 for death prevented [based on CTT meta-analysis]
Primary prevention: NNT ~104–217 for non-fatal MI
NNT reflects individual probability, not population impact
At scale, these numbers prevent millions of deaths
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@thalesnemo @Kansanparantaja @Backto198433421 @MeTheAngryCat @nicknorwitz COIs: Fully disclosed in each paper. Industry ties ≠ data fabrication. The Mendelian randomization studies use genetic data. No pharma can pay to change your DNA.
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