Riham Katkhuda MD

Recent advances in immunohistochemistry and molecular techniques have recognized an expanding number of renal tumor types. This presentation will address the emerging entities in renal tumor pathology, with emphasis on clinical implications. ow.ly/STuC50WbNw4

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Unique pattern of an uncommon #testis tumor. What’s is your diagnosis #GUPath tweeps? #OnePicDx Answer in comment👇👇👇

Kidney; Eosinophilic vacuolated tumor (EVT): Other oncocytic tumor (WHO 5th). Solid growth of eosinophilic cells with cytoplasmic vacuolation and prominent nucleoli with large vessels at periphery. CD117+Cathepsin+CK7- TSC1,TSC2 or MTOR mutations #GUPath #PathX #PathTwitter

Renal sinus mass: Anastomosing hemangioma (lesion mimicking angiosarcoma);anastomosing vascular channels lined by hobnail cytologically bland endothelium. Vascular thrombi and sclerosis between the proliferating vessels present #GUpath #pathology #PathTwitter

These are images of a 3.0 cm kidney mass in a 45 yo man.

Cleveland Clinic soft tissue pathology course starts in 7 days!! May 15-18. 150 digital cases. 15 sessions with staff. VIRTUAL option. Everything will be RECORDED and available on demand!!#PathTwitter na01.safelinks.protection.outlook.com/?url=http%3A%2… @ClevelandClinic @CleClinicMD @CAPA_comm @ISBSTP @TheUSCAP

Orchidectomy, adult #GUpath #GIpath #Pathresidents #pathwtitter

Bladder lesion, transurethral resection: Prostatic adenocarcinoma #PathTwitter #pathology #PathX #gupath #ProstateCancer

Exceedingly rare but diagnosable with #OnePicDx!🕵️‍♂️ What is your diagnosis on this #urinarybladder tumor with unique histology? Answer in comment. #GUPath👇👇👇

@Dramanyhassany1 HEG1. Yes it is mesothelial marker

@riham_katkhuda What is the first marker? Is it mesothelial marker?

82 Y/O, F with uterus mass. Peritoneum biopsy: Positive for high-grade carcinoma. P53: aberrant expression (positive diffuse) ER: Negative This immunophenotype, in conjunction with morphology and clinical presentation would favor müllerian origin #gynpath #gynecologic_cancer

Eosinophilic solid and cystic RCC: Previously oncocytoid RCC after neuroblastoma. Solid/cystic architecture, voluminous eosinophilic cytoplasm with vacuolization and basophilic cytoplasmic stippling. TSC1/TSC2 mutation/mTOR upregulation. CK20+#gupath #PathX #PathTwitter

Low power view diagnosis of this renal mass with distinctive morphology? #GUPath #OnePicDx Answer is all in the picture👇

Amazing system developed by @ScotRobertsonMD and team from our group @CLEClinicLabs! Searching pathology reports doesn't have to be difficult!

Low-grade oncocytic tumor of the kidney is in emerging subtype of renal neoplasm that previously was likely diagnosed as either oncocytoma or eosinophilic chromophobe RCC. However, recent work shows that it has different immunohistochemistry and genetics. CK7+GATA3+CD117 -#GUpath

Malakoplakia of the kidney: Histiocytes with eosinophilic cytoplasm and round nuclei (Von Hansemann) admixed with variable inflammatory infiltrate. Few small rounded concentric basophilic intracytoplasmic inclusions(Michaelis-Guttman bodies) (PAS stain)#GUpath #pathX

🚨 #publicationalert #gupath Excited to share our latest work! Atypical Intraductal Proliferation in Prostate Needle Core... : The American Journal of Surgical Pathology journals.lww.com/ajsp/abstract/…

Bladder mass in middle age man

Urinary bladder, transurethral resection: Small cell neuroendocrine carcinoma , arising in a background of urothelial carcinoma. Carcinoma invades muscularis propria. Synaptophysin + #GUpath #pathx #pathTwitter #pathology