Robert Matney

4 days out from my life-changing surgery, @Aetna has denied the appeal for my brain surgery. to be clear, when i signed up to aetna months ago, the coordinator had confirmed they would cover this surgery. then, a week ago, they said the surgery was too experimental/elective and denied coverage. we appealed. that appeal was just denied today. now, my neurosurgeon is trying to do a peer-to-peer consult with someone at aetna to explain why i need it so we don’t lose the surgery date on monday morning. aetna is not being responsive. this is sadistic and a violation of basic trust. please spread this so they can’t ignore it. they may not care if i live or die but people should know just what kind of company they’re dealing with. and please pray they are able to have a peer-to-peer consult with my neurosurgeon and have a change of heart.

#ScienceSaturday ❓ Can AI help us engineer better cancer therapies, one protein at a time? ➡️ A new study in Science reveals how generative AI is being used to rapidly create de novo protein minibinders to target cancer-associated peptide–MHC complexes (pMHCs), which are key triggers for T cell activation. ➡️ Using tools like RFdiffusion, AlphaFold2, and ProteinMPNN, researchers engineered minibinders that mimic T cell receptors and bind to tumor-specific pMHC targets like NY-ESO-1. When incorporated into CARs, these AI-designed molecules enabled T cells to kill #melanoma cells in lab experiments. 🌟 This approach could streamline and personalize T cell therapies, especially in cancers where conventional TCR discovery is too slow or difficult. It opens a path to designing synthetic proteins in weeks, not years, with built-in specificity and potency. 🔗 Read more in @ScienceMagazine: science.org/doi/10.1126/sc… @TimothyPJenkins @KrisHaurum @DTUtweet @DTUbioengineer #CancerResearch #AI #Immunotherapy #CancerImmunotherapy