Robin Sebastian
45 posts

Robin Sebastian
@rob_seb_
Assistant Professor at Lewis Katz School of Medicine, Temple University
DC, United States Katılım Haziran 2019
85 Takip Edilen99 Takipçiler

Want to know how homologous recombination defects are caused upon loss of BRCA2? Check out our recent efforts in uncovering this phenomenon just out in Science! science.org/doi/10.1126/sc…
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@EricGSun @RebeccaStarble @SStevenWang @nitinroper Congratulations, Eric and Rebecca! Glad to see this work in print
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Robin Sebastian retweetledi

Excited to share this work with @RebeccaStarble (please see tweetorial!)
Very thankful to our funders and collaborators especially @SStevenWang, Politi Lab, Wang Lab @ UCR, and @nitinroper
Rebecca Starble@RebeccaStarble
Excited to see my PhD work out! Here, we find an unexpected epigenetic mechanism that regulates oncogene amplification to promote tyrosine kinase inhibitor resistance in lung adenocarcinoma. Tweetorial below! ⬇️ nature.com/articles/s4159…
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Cytarabine has been the mainstay for AML treatment. This chemotherapy can lead to problems with movement and balance. Here we explain this neurotoxic side effect: nature.com/articles/s4158…. Work led by Jia-Cheng Liu, Donpgeng Wang, Elsa Callen and many terrific collaborators!
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Thrilled to share our latest work in @Nature! We show how cancer cells navigate DNA replication despite DNA damage, revealing new insights into genome stability. Huge thanks to my incredible collaborators! Check it out here: nature.com/articles/s4158…
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@rob_seb_ @SarahLa47195747 @Nature Congratulations to Robin, Mirit, and coauthors on this fantastic work!
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@FaltasLab @EricGSun @Nature Thanks. We haven’t tested if the chromatin accessibility has anything to do with DSB-specific local inhibition of replication. I don’t expect local chromatin changes to influence replication so much
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Excited to share a story spearheaded by the incredible @rob_seb_ where we describe a fundamental genome maintenance mechanism linking DNA replication with double-strand breaks @Nature!
nature.com/articles/s4158…
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Thank you @EricGSun for the wonderful summary. It was a pleasure working with you!
Eric Sun@EricGSun
Excited to share a story spearheaded by the incredible @rob_seb_ where we describe a fundamental genome maintenance mechanism linking DNA replication with double-strand breaks @Nature! nature.com/articles/s4158… 🧵👇 1/n
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Exciting news! 🎉 After a long journey, my postdoctoral research is finally published! 🌟 While we often hear about telomere depletion with age, have you ever wondered what happens to our centromeres? 🤔 In this study, we show how centromeres weaken and ways to reactivate it !!
Molecular Cell@MolecularCell
Online Now: Centromere inactivation during aging can be rescued in human cells dlvr.it/THKs3M
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Delighted to share our latest publication in Nature Scientific Data. It was fantastic working with the groups of @iam_Mridula (IISER Pune), Anupam Gupta (IIT Hyderabad) and Rajakumara Eerappa (IIT Hyderabad).
nature.com/articles/s4159…
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