Ruhollah (Roohy) Shemirani

📢Excited to share our comprehensive review led by @EstherHL5 on gene-environment interactions. Within, you'll find: 🛠️Summary of current methods by underlying hypothesis 🗺️Framework for considerate epidemiological modeling 🗣️Call for greater contextual diversity needed for GxE

Our work on fine-scale identity-by-descent clusters in the UCLA ATLAS Biobank was published online today! I'm immensely proud of this work and its implications for the health of diverse populations in my home, Los Angeles 🌴 nature.com/articles/s4159…

An international team of scientists has assembled the first human “pangenome” – a more representative reference genome that captures almost all the genetic variability residing in the DNA of humans around the globe. Dr. @EimearEKenny shares more: mshs.co/3LZ2ImA

Announcing the first draft of the new human 'pangenome' reference representing 47 diverse humans, ~120M new bp, >1000 new gene dups. Congrats to @khmiga @BenedictPaten @lh3lh3 @irahall9 @tobiasmarschal @erikgarrison and all in the @HumanPangenome nature.com/articles/s4158…

New Preprint 🚨, excited to share our work @SinaiGenHealth @EimearEKenny 🧬on peripheral artery disease (PAD). We identify a new PAD risk locus in Dominicans in the BioMe Biobank. Thanks to all involved including @genandgenes, @damrauer and the MVP team. medrxiv.org/content/10.110…

Super excited to share a preprint of work from my PhD with @JeremyJBerg 🎉 biorxiv.org/content/10.110…

#msprime running in the browser with genuinely respectable performance via Pyodide magic. Amazing! Early preview of the possibilities here, I'm sure this will be a killer app for teaching. Nice one Ben!💪

Hard to overstate how big a milestone this is for the #tskit project - this is the start of "Long Term Support" for the C API. You can build your C/C++/RCpp/whatever application with tskit support built-in and be sure of long-term stability. 1/3

Essential reading for those in human genetics research. Outlines our ongoing responsibility to understand how research is used and twisted in white supremacist ideologies with suggested paths forward so that we can actively work against it. 🧵👇🏼

Human genetics has a diversity problem. Not just in terms of study pops, but also in who asks the questions. We urgently need diversity in our research teams re: expertise and lived experiences to better see each others blind spots and do better. Let me explain. 🧵(1/N)

Dear PIs in genetic/genomics, I know a brilliant young scientist from Iran looking to expand her experience before starting a Ph.D. If you are looking for an intern, please DM me for more info/CV.

Mr Lordi, singer of Finnish heavy metal band Lordi, receives his second dose of Covid-19 vaccine in Rovaniemi, Finland on August 1, 2021.

@EimearEKenny @popgenepi Looking forward to doing this work for the foreseeable future!! 🙏🙏🙏🤞

@roohys @popgenepi That was a very fortunate day for us too and for computational genomics 😊😊 🧬🧬🧬🧬💻💻💻💻

Check out our paper on iLASH: our scalable IBD detection algorithm for accurate analysis of biobank-scale datasets. A close collaboration between @USC_ISI, @CUAnschutz , and @SinaiGenHealth.

@GillianBelbin @EimearEKenny @popgenepi Glad you're back!!! You are very kind as always 🙏. I am also very proud of this 5-year project of ours! Add to that the fact that we get to continue doing this stuff...

We also included a deep analysis of IBD networks in the PAGE study and UK Biobank datasets in the paper in which Dr. Belbin provides great population genetics insights only available through the analysis IBD nets.

All of this prallelization is automatic, you do not need to deal with complicated computing cluster configuration to benefit from it.