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I write about how people become their healthiest, fittest selves — and how those outcomes scale through technology, incentives, and better systems.
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Ryan Roddy
299 posts
Ryan Roddy
@ryanproddy
Human performance. Modern health. Systems that scale. Managing Partner @ Seaside Ventures Writing → https://t.co/xFFNjsAO8U
Austin, TX Katılım Mayıs 2018
537 Takip Edilen272 Takipçiler
9/ I wrote about that path from injury, to peptides, to why oligos feel like the next layer—here: open.substack.com/pub/ryanproddy…
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8/ That’s why they feel less like drugs and more like software.
Programmable. Precise. Still early, but very real.
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1/ I didn’t get into peptides because they were trendy.
I got into them because my body was pretty broken. 🧵
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Amazing work by @jgebbia and team. Can’t believe it’s taken this long for the government to incorporate good design for its public materials. Should amplify impact
keshav@kshvbgde
I can't believe this is a government website what the fuck.
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The interesting part of ChatGPT Health isn’t better answers.
It’s that interpretation just became cheap — and healthcare has been built around interpretation being scarce
OpenAI@OpenAI
Introducing ChatGPT Health — a dedicated space for health conversations in ChatGPT. You can securely connect medical records and wellness apps so responses are grounded in your own health information. Designed to help you navigate medical care, not replace it. Join the waitlist to get early access. openai.com/index/introduc…
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@nickaturley Big opportunity to control where care and dollars flow next by controlling the data layer
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Today we’re launching ChatGPT Health.
People already use ChatGPT to understand test results, prepare for appointments, and make sense of what they’re dealing with. Health brings all of that into a dedicated, private home, with the ability to securely connect apps and medical records.
We’re starting with a small group of users from the waitlist and will expand access over the coming weeks.
Learn more: openai.com/index/introduc…
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@gdb Amazing but healthcare hasn’t been blocked by intelligence, it’s been blocked by fragmentation and misaligned incentives
AI only matters once it collapses the stack into something the user (not the system) controls
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@dr_ericberg Agreed! If a “healthy” input makes things worse, the system underneath isn’t healthy yet
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Testing gut health can be as simple as removing fiber.
Avoid fiber for three days, then reintroduce it for three days. Feeling worse after adding fiber may point to gut issues.
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@calleymeans Most food today is designed to scale margins, not health. Eating real food is basically a system override
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@thegarybrecka Fat loss isn’t linear math. Push scarcity too long and the system pushes back harder
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@Hybridathlete Most people train in bursts. The body only rewards what shows up year round
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It's very easy to beat yourself into the ground working out 5-6 days/wk for 2-3 weeks at a time, a few times per year.
It's much more difficult to consistently work out 3-4 days/wk, without missing a week, for an entire year.
But if you do, your entire life will change.
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@TokuHealth Belief doesn’t move biomarkers. Systems do—and the ones that get built earliest compound the longest
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Gentle reminder that you can't will your arteries to clear or manifest a higher VO2 max
But you can test your ApoB, adjust your supplements, train zone 2 & 4 cardio
Then re-test in 90 days
Reality only bends to those willing to chase it
We are starting to figure out that cardiovascular disease is predictable enough that the data lets you intervene before it becomes too late...
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@m_franceschetti The problem isn’t beer vs wine—it’s that recovery debt accrues quietly, long before performance feels off
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I was curious whether the type of alcohol actually matters for recovery, not just drinking vs. not drinking.
So we looked at 2,600+ nights of sleep and cardiovascular data.
What stood out:
• Any alcohol strains cardiovascular recovery (↑HR, ↓HRV)
• HRV: liquor and wine decreased HRV the most per drink (−3.8%, −3.6%)
• HR: mixed drinks increased HR the most per drink (+2.0%)
• Beer had the smallest impact, but it was still measurable, with HR increasing by ~1.2% and HRV down by ~1.6%
Mixing alcohol types lowered HRV more than beer alone (−3.0% vs. −1.6%).
The surprising part:
Most people felt "fine" the next morning, even when HRV dropped by up to 15% (after 4 drinks).
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@Dr_Singularity 🙌🏼 Healthcare changes when data stops being episodic and becomes ambient. AI is the layer that finally makes that usable
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"AI now predicts 130 diseases from 1 night of sleep"
AI is getting crazy, what an insane and amazing technology
Rohan Paul@rohanpaul_ai
AI now predicts 130 diseases from 1 night of sleep 🛌. Newly nature-published research brought SleepFM, a foundation model trained on 585K hours of sleep recordings from 65K participants, combining brain, heart, muscle, and breathing data. Polysomnography (PSG) records brain, heart, muscle, and breathing signals during sleep, but most AI only stages sleep or flags apnea. SleepFM pretrains on 585,000h of PSG from 65,000 people and turns 1 night into a general sleep embedding. From 1 night, 130 diseases hit Harrell’s concordance index (C-Index) of at least 0.75, which checks whether higher predicted risk happens sooner, including mortality 0.84 and dementia 0.85. Older supervised models use less data, need expert labels, and break when clinics record different channel sets. SleepFM resamples to 128Hz, makes 5s tokens, uses 1D convolutions, pools channels with attention, then a transformer summarizes time. Leave-one-out contrastive learning trains each modality to match the average of the others, so missing modalities hurt less.
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