Luca Schulz

343 posts

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Luca Schulz

Luca Schulz

@schulluc

enzymes @GoogleDeepmind | previous @EMBOFellows, @GreenGroupMIB, @erblabs, and @kahochberg

London, UK Katılım Şubat 2014
273 Takip Edilen662 Takipçiler
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Luca Schulz
Luca Schulz@schulluc·
Super excited to share my 1st first-author publication out today in @ScienceMagazine, in which we resurrect billion-year-old enzymes to study the evolution of Rubisco. Let me tell you how a 100 amino acid protein facilitated the rise of oxygenic life. science.org/doi/10.1126/sc…
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Johannes Rebelein
Johannes Rebelein@RebeleinLab·
Congrats to @Leo_Ernst_2 for successfully defending his PhD thesis @mpi_marburg !🎊🍾🎉🥳 The first doctor from the Rebelein lab.
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Green Research Group
Green Research Group@GreenGroupMIB·
Delighted to announce that 'Engineered enzymes for enantioselective nucleophilic aromatic substitutions' is out now in Nature! Congratulations to Tom, George and everyone else involved in this project! 🎉🎉🎉 nature.com/articles/s4158…
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Franziska Sendker
Franziska Sendker@SendkerFL·
Happy to share our story on evolution of protein quaternary structure! We discover an astounding variation in assembly across evolutionary timescales contrasted by strong functional conservation suggesting a significant role of non-adaptive processes nature.com/articles/s4146… 👇🧵
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SYBORG
SYBORG@erblabs·
We are looking for a postdoc - in a project on a UbiD like (de)carboxylase!
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Helena Schulz-Mirbach
Helena Schulz-Mirbach@mirbachh·
Lets talk about #acetyl-CoA! As central molecule in C1 metabolism, the efficiency of its assimilation determines yields. Read below about our Lcm as novel activity in the shortest O2 tolerant route to make pyruvate from acetyl-CoA while fixing #CO2! nature.com/articles/s4146…
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Luca Schulz
Luca Schulz@schulluc·
For some more fun biochemistry (& a lot of cool evolutionary implications) I recommend that you check out the publication and/or message me! A huge thanks to my mentors @KaHochberg and @erblabs, as well as all co-authors, who have been crucial in getting this work done.
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Luca Schulz
Luca Schulz@schulluc·
Focusing on substitutions that occurred in such regions, we identified historical changes that drastically reduced Rubisco’s activity but whose negative effect is buffered by the presence of the SSU.
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Luca Schulz
Luca Schulz@schulluc·
New in @EMBOjournal, we studied the evolution of essentiality in Form I Rubisco. While @KaHochberg nicely summarizes the evolutionary implications of our work, let me summarize some of the cool biochemistry surrounding it. doi.org/10.1038/s44318… 🧵
Georg Hochberg@KaHochberg

New paper from us and @erblabs by @schulluc : embopress.org/doi/full/10.10…. It's about the evolution of essentiality. This question has fascinated me for a long time: How does a component that was previously unnecessary for some function become essential for it?

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