Ganesh

@lavvspan Thank you! First meaningful and nuanced post I have read in a long time. Not as exciting as “don’t need carbs as a fuel during endurance exercise “ 🤣

This paper is one of the clearest demonstrations ever published that there appears to be an upper physiological limit where extreme endurance exercise can temporarily overwhelm even a highly trained heart. Researchers followed a former professional ultra-endurance athlete during two world-record cycling attempts: one lasting 12 hours, and another lasting 24 hours. The athlete was not recreationally fit. He was exceptionally conditioned, with a VO2max between 67–73.5 mL/kg/min, values roughly 190–209% of predicted norms for his age. He could sustain extraordinarily high workloads for prolonged periods. During the 12-hour attempt, he averaged 253 watts and maintained roughly 71% of maximal heart rate while covering over 491 km. Afterward, researchers observed what sports cardiology commonly refers to as “exercise-induced cardiac fatigue”: temporary reductions in left and right ventricular function, elevated BNP and troponin levels, and signs of myocardial stress. However, despite being exhausted, he had no respiratory distress, no pulmonary edema, and all cardiac parameters normalized within 14 days. The 24-hour attempt was different. The athlete maintained an astonishingly high workload for a full day: 231 watts on average, 73% of maximal heart rate, nearly 900 km ridden, and approximately 92% of the speed sustained during the 12-hour event. Immediately afterward, he developed acute respiratory distress. Researchers documented tachypnea, audible lung crackles, productive coughing of pink frothy sputum, and orthopnea, all classical signs of cardiogenic pulmonary edema and acute heart failure. The biomarkers were profound: BNP increased more than 100-fold, reaching levels over five times the upper normal limit. Troponin-I increased 16-fold. Both left and right ventricular function dropped dramatically, with ejection fractions entering ranges commonly seen in clinical heart failure patients. Importantly, this was not simply “dehydration” or generic exhaustion. The study used echocardiography, cardiac MRI, strain imaging, exercise MRI, biomarker analysis, and repeated follow-up evaluations. Multiple independent measurements pointed toward the same conclusion: the athlete’s cardiovascular system temporarily crossed from cardiac fatigue into acute cardiac failure. One of the most interesting findings was the apparent dose-response relationship. The same athlete tolerated 12 hours with only transient dysfunction. At 24 hours, under similarly high intensity, the system failed. The authors propose that cardiac stress is not determined by duration alone, but by the interaction between duration and sustained intensity. In simple terms: the heart may tolerate long exercise, and it may tolerate high intensity, but sustaining both simultaneously for extreme periods may eventually exceed physiological reserve. Another major finding involved the right ventricle. Previous endurance studies already suggested the RV is especially vulnerable during prolonged exercise because pulmonary artery pressures rise substantially during endurance work, while the RV wall is thinner and less equipped to tolerate prolonged pressure overload. This study reinforced that concept. The athlete’s RV dysfunction was consistently worse than the LV dysfunction after both events. Yet perhaps the most important conclusion is not about damage, but recovery. Despite developing what objectively resembled acute heart failure, the athlete eventually recovered fully. Biomarkers normalized. Ventricular function returned to baseline. MRI showed no evidence of permanent fibrosis or persistent myocardial injury months later. That distinction matters enormously. This paper does not suggest endurance exercise is inherently dangerous. The overwhelming body of evidence still shows endurance training dramatically improves cardiovascular health, longevity, insulin sensitivity, mitochondrial function, metabolic flexibility, and all-cause mortality. The athlete in this paper represents the absolute edge of human performance physiology, not normal athletic practice. The real lesson is more nuanced: Human physiology adapts remarkably well to stress, but adaptation still operates within biological limits. Recovery is not weakness. Recovery is part of the stimulus. The modern fitness culture often glorifies relentless output, chronic exhaustion, sleep deprivation, and accumulating training load without respecting physiology. This paper argues against that mindset. Even an elite athlete with world-class conditioning eventually reached a threshold where output exceeded recovery capacity in real time. For most athletes and health-oriented individuals, the practical evidence-based approach is clear: Build a strong aerobic base. Train consistently, not heroically. Use high intensity strategically. Periodize training loads. Monitor sleep, HRV, resting heart rate, mood, motivation, and recovery capacity. Fuel long sessions appropriately. Reduce training aggressively when systemic fatigue accumulates. Understand that adaptation occurs during recovery, not during destruction. The strongest athletes are not the ones who can suffer endlessly. They are the ones who can apply stress intelligently, recover efficiently, and remain durable for decades.

@Abhishek060722 NO!!!!! How dare you even ask that question????

Genuinely asking, do all CSK fans want Hardik Pandya in CSK?🤔

@fluidathletics 🤣

@sganny That’s ridiculous

6 months until my marathon debut Yomif Kejelcha set a high bar but I’m not shying away from competition Project 1:59:40 has begun

@pratyush_no7 This proves that Chennai cricket fans are nerdy and special!!! 🤣🤣🤣

A kid 🗣️ - “Brevis sir be careful, you might get Timed out while kneeling down before going to bat ?” 😂 Dewald Brevis 🗣️ - “Now I'll make sure I make it in time for everyone. I do run-up after I kneel down. But thank you for the reminder, I appreciate it and I'll remember that whenever I play again.” (laughs 😂)

@thegarybrecka Agree but I wake up at 6 and not having coffee (with milk) till 9am is really hard. I don’t have it right away and wait for an hour and half but waiting for 3 hours takes a toll.

If you finished dinner by 7 PM last night and skip breakfast until 9 AM, you just completed a 14-hour fast. No extreme discipline. No starvation. Most of it happened while you slept. Here is what occurred in that window. Insulin dropped to its lowest point of the day. Fat burning switched on. Autophagy began clearing damaged cellular debris. Growth hormone spiked overnight. You do not need a 72-hour fast to get the benefits. A consistent 12 to 16 hour window is enough to shift your metabolism, improve insulin sensitivity, and activate your body's repair systems.

@Houseofyogi Remind me again why the merger with jet blue or someone other airline was not resurrected again in the last 16 months? House, senate and presidency was with who this last 16 months?

Spirit Airlines died tonight at the hands of the socialist crusader, Elizabeth Warren She must be so proud to add another casket to her achievements. Tonight at 3am, Spirit turns off the lights. 14,000 jobs gone. 30+ smaller airports lose service. JetBlue offered $3.8 BILLION in cash to buy Spirit in 2022. Shareholders, flight attendants union, literally everyone voted yes. The combined company would have held 9% of the US market against a Big 4 that already owned 80%. For anyone who understands numbers: 9% isn’t a monopoly against 80%. Warren said no. She wrote letters. She pressured Buttigieg. Biden’s DOJ sued. A federal judge killed the deal in January 2024. Her argument: the merger would cost consumers $1 billion a year. Now look at her collateral damage she dusts under the rug. 510 pilots gone in the months after. 1,800 flight attendants furloughed in December. 14,000 jobs in 2023. 7,500 last week. Zero tonight. And that’s just the people in Spirit uniforms. Catering goes. Fuel guys go. Baggage crews, gate agents, airport coffee shops, hotels and rental cars in 70 cities Spirit flew to. Every airline job carries 3 more on its back. 40,000 people out of work because of one woman’s moronic crusade against the market. And the math ain’t mathing. Spirit abandoned 90 routes during the death spiral. Fares on those routes are up 14% on average. Oakland to Newark: $135 to $288. Fort Myers to San Juan: $92 to $219. Kansas City to Newark up 66%. That’s reality. Not some BS number from a “study.” So @SenWarren tell me how this saves the consumer money? Cheap carriers in a market drop fares 21% across the board. Southwest did this in the 90s and saved Americans $68 BILLION over 20 years. Warren killed it. That’s what moronic politicians led by socialism do. Then with her own blind arrogance, she tweeted Spirit’s collapse is “a Biden win for flyers.” A win. 14,000 people are reading termination letters tonight. And she’s taking credit. This is socialism in 2026. A senator who’s never made payroll thinks she knows how to run a market better than the people who own and work in the company. She saved you a billion on imaginary paper. She cost you ten times that in real life. She didn’t protect consumers from anything. 14,000+ will go from working to welfare. She will make sure to blame billionaires, hardworking tax payers, AI, capitalism and whatever monster they will make up tomorrow hiding under your bed. Higher taxes. Fewer jobs. More expensive everything. She called it a win. I hope you enjoy winning.

@BabajiSutar3 Why is Walsh not in this list?

Only one Batsman and one Bowler you need to choose from below Team XI ! Which two players will you choose? Comment 👇 Mine Sir Gordon Greenidge and Malcolm Marshal !

@bagga_buntyy Sadhanand Viswanath, Chetan sharma, Manoj Prabhakar

@CSKian716 Gavaskar: that’s not a dive it’s a collapse 🤣🤣🤣🤣

DUBE PLS FCUK OFF. I've had enough. Dropped more catches than the runs he has scored. Why tf does Rutu not sit him out as an IP. Is he braindead?

@Ndlombango You figure out with experience that high volume is key to running fast

Why is it that marathon runners become better runners the older they grow?

@stevemagness Forget back in the day. I am such a cheapskate, even today, I dump ice from the ice tray in my freezer into my bath tub for an ice bath 🤣

Back in the day, you’d buy a $2 bag of ice and dump it in a tub for an ice bath. Now, it seems you buy an $8,000 bath tub. Never underestimate the commercialization of everything.

@ipnfinity AKA solution looking for a problem?

There's always humans with their briliant idea 😱🤔

@karagoucher @Cathal_Dennehy I was super disappointed when Ruth’s decision came out but haven’t given up on the sport. Disagree with you that just because shoe and bicarbonate have changed the sport,sub 2 wasn’t humanity changing. Yes you said for you it didn’t but it did for me, so let’s leave it at that 🤣

@karagoucher @Cathal_Dennehy Listened to the pod on my run and now I know why I love your pod so much. It was a master class of how to keep two opposing thoughts in your mind and struggle through the conundrum! Btw, I may be an exception but my reaction after Ruth’s sub 2:10 was x.com/sganny/status/…

Scepticism is understandable - and healthy - any time a world record falls, but this is an important detail in the story of Sebastian Sawe and what he achieved in London today.

@Snehalsays_03 Why was there a camera in the kitchen?

That's how things should be in a marriage 🌻🫶🏻

@karagoucher @Cathal_Dennehy Yes would be very happy to see the full data. But also, this quote is from the head of AIU, an org that you also high very high regard for. This is not a quote from the athlete, his coach, his agent or his sponsor. Has to carry some additional weight, no?

@sganny @Cathal_Dennehy Look, I’m actually not doubting Sawe. But this quote proves nothing. I was often tested 20+ times a year. And “a lot of the tests containing the full suite of analysis” is not a number or proof. This whole testing program was done to prove he is doing this clean- so show it!

@karagoucher @Cathal_Dennehy Yes I know who you are.Lots of respect for what you have done. Read your book (never bought Nike for myself after reading the book), listened to every episode of nobody asked us,except the London live show. Saving it for today’s long run. Just want to celebrate humanity for a sec

For those wondering if we can trust this new 1:59:30 marathon world record by Sabastian Sawe since there have been so many Kenyan runners caught doping and using performance-enhancing drugs in recent years...it’s always hard to have 100% certainty, but credit to Sabastian Sawe, his agency and his sponsor (adidas) for doing their best to be transparent. Some context for folks: Adidas included a budget in Sawe's contract to provide funds to the sport’s anti-doping organization (the Athletics Integrity Unit) of about $50,000 to test him. Basically, they wanted to prove he was clean, as there was growing confidence that he would break the marathon world record of 2:00:35 set in 2023 by the late Kelvin Kiptum. They also wanted to avoid the doubt of Ruth Chepngetich breaking the women’s marathon world record in 2:09:56…and then having that skepticism validated when she tested positive for a banned substance. Sawe was reportedly drug-tested 25 times (this included blood and urine) in the space of two months in the lead-up to last fall's Berlin Marathon and that’s a pretty high number. He was not tested as frequently before this race but his coach Claudio Berardelli confirmed that the Athletics Integrity Unit sets the testing regimen and that he is on a higher frequency of testing than other athletes in 2026 because of the additional funding being provided.

@karagoucher @Cathal_Dennehy letsrun.com/news/2026/04/1…

@Cathal_Dennehy Would be great to see how many times, exact dates, when they fell in training, what was tested for, etc. If the point is to prove he's clean, I'd love it if they would show the data. Great he's been doing it, but for the skeptics they, understandably, need to see the proof.