Luis A. Vegas Vicentini
18.5K posts

Luis A. Vegas Vicentini
@lavvspan
I empower individuals with evidence based nutrition, lifestyle, strength and endurance coaching to optimize health, and lifespan. Metabolic Health Coach.
Katılım Ekim 2021
479 Takip Edilen1.6K Takipçiler

@CaracasChron A masterclass in playing the game of politics
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🫓 MCM dribbling Trump again:
“We Venezuelans value, appreciate, share the values of the American people (...) In terms of legacy imagine what (democracy in 🇻🇪) will mean for the US: after we're free, 🇨🇺🇳🇮 will follow. A continent finally free of communism and dictatorship.”
Erin Burnett OutFront@OutFrontCNN
Nobel Peace Prize winner Maria Corina Machado on Trump floating Venezuela as America’s 51st state. Her interview with Erin tonight:
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Luis A. Vegas Vicentini retweetledi

Blood NAD+ may not be the aging biomarker many hoped for.
Across 7 human cohorts, whole-blood NAD+ levels stayed remarkably stable with age and lifestyle changes—shifting mainly with nicotinamide riboside supplementation. #Aging #NAD #Longevity
nature.com/articles/s4225…

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@Mollyploofkins Just like the statues of Hitler, Stalin, Gaddafi, Hussein, and Chávez were eventually torn down, this too will be demolished when its time comes.
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@Mollyploofkins Well, if there’s no active civic engagement to fight these, then tyrants pretty much get away with it
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Luis A. Vegas Vicentini retweetledi

One of the most underrated health foods on the planet:
Frozen blueberries.
Anthocyanins are the deep purple pigments that fight inflammation, protect your brain, and lower your risk of heart disease.
Fresh blueberries start losing them the moment they're picked. After 1-2 weeks in the fridge, up to 50% can be gone.
Frozen blueberries are flash-frozen within hours of harvest and retain up to 95% of their nutrients.
The best part is they're tasty. I put these into my Greek Yogurt breakfast every morning.

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FACT:
If a historically sedentary GLP-1 patient does not learn to eat whole foods, improve lifestyle habits, implement resistance and aerobic training, and restore proper circadian hygiene, there is a high probability they will end treatment in a more frail state.
GLP-1 drugs can improve glucose control and help reduce body weight, but they do not automatically rebuild muscle, improve fitness, restore sleep quality, or fix the root causes of metabolic dysfunction.
Without lifestyle change, many patients lose lean mass alongside fat and remain metabolically fragile.
These drugs are powerful tools.
They are not a cure.
Medscape@Medscape
Recent headlines have alarmingly stated dramatic muscle loss for patients on GLP-1s. Yoni Freedhoff, MD, explains why this is a manufactured controversy. Tap the link to read the full commentary: mdsc.pe/42UswJe
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FACT:
If a historically sedentary GLP-1 patient does not learn to eat whole foods, improve lifestyle habits, implement resistance and aerobic training, and restore proper circadian hygiene, there is a high probability they will end treatment in a more frail state.
GLP-1 drugs can improve glucose control and help reduce body weight, but they do not automatically rebuild muscle, improve fitness, restore sleep quality, or fix the root causes of metabolic dysfunction.
Without lifestyle change, many patients lose lean mass alongside fat and remain metabolically fragile.
These drugs are powerful tools.
They are not a cure.
English

Recent headlines have alarmingly stated dramatic muscle loss for patients on GLP-1s. Yoni Freedhoff, MD, explains why this is a manufactured controversy. Tap the link to read the full commentary: mdsc.pe/42UswJe

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@StellarVoyager1 @OutFrontCNN The stench of resentment is strong in this one…
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@Perez1oj @MariaCorinaYA giving a masterclass in diplomacy and strategic thinking.
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I guess some might credit her for sticking to her talking points regardless of Trump's craziness...discipline! But others will point to the inability to criticize even the most outrageous BS from Trump...it sort of encapsulates the vise in which the opposition is caught!
Erin Burnett OutFront@OutFrontCNN
Nobel Peace Prize winner Maria Corina Machado on Trump floating Venezuela as America’s 51st state. Her interview with Erin tonight:
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Luis A. Vegas Vicentini retweetledi

Johnson’s Blueprint Has a List of Dos and Don’ts for Longevity Hackers
Dr. Oliver Zolman, the medical mind behind Bryan Johnson’s Blueprint, reveals why most longevity advice is ‘biohacking theatre’ and shares 2026’s essential dos and don’ts for real healthspan.
🔗inc.com/chase-feiger/t…
By @ChaseFeiger

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@AdamKinzinger I wonder if we’re ever gonna find out what Putin has on Trump…this level of betrayal to historical allies is criminal.
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They’re literally helping Russia on purpose
POLITICO@politico
Hegseth again stuns Pentagon with Poland troop withdrawal dlvr.it/TSXv2w
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@Telegraph Wonder what was the average passenger age in that cruise ship
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Hantavirus can remain in human semen for up to six years and has the potential for sexual transmission even after a person has recovered, according to a peer-reviewed study.
🔗: telegraph.co.uk/global-health/…

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@BondLeBon Otro trabajo más que afinca, nuevamente, este clásico refrán:
Todo en exceso, es malo.
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@lavvspan ¿Este trabajo en el fondo no es un poco "el agua moja"?
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This paper is one of the clearest demonstrations ever published that there appears to be an upper physiological limit where extreme endurance exercise can temporarily overwhelm even a highly trained heart.
Researchers followed a former professional ultra-endurance athlete during two world-record cycling attempts: one lasting 12 hours, and another lasting 24 hours. The athlete was not recreationally fit. He was exceptionally conditioned, with a VO2max between 67–73.5 mL/kg/min, values roughly 190–209% of predicted norms for his age. He could sustain extraordinarily high workloads for prolonged periods.
During the 12-hour attempt, he averaged 253 watts and maintained roughly 71% of maximal heart rate while covering over 491 km. Afterward, researchers observed what sports cardiology commonly refers to as “exercise-induced cardiac fatigue”: temporary reductions in left and right ventricular function, elevated BNP and troponin levels, and signs of myocardial stress. However, despite being exhausted, he had no respiratory distress, no pulmonary edema, and all cardiac parameters normalized within 14 days.
The 24-hour attempt was different.
The athlete maintained an astonishingly high workload for a full day: 231 watts on average, 73% of maximal heart rate, nearly 900 km ridden, and approximately 92% of the speed sustained during the 12-hour event.
Immediately afterward, he developed acute respiratory distress. Researchers documented tachypnea, audible lung crackles, productive coughing of pink frothy sputum, and orthopnea, all classical signs of cardiogenic pulmonary edema and acute heart failure.
The biomarkers were profound:
BNP increased more than 100-fold, reaching levels over five times the upper normal limit. Troponin-I increased 16-fold. Both left and right ventricular function dropped dramatically, with ejection fractions entering ranges commonly seen in clinical heart failure patients.
Importantly, this was not simply “dehydration” or generic exhaustion.
The study used echocardiography, cardiac MRI, strain imaging, exercise MRI, biomarker analysis, and repeated follow-up evaluations. Multiple independent measurements pointed toward the same conclusion: the athlete’s cardiovascular system temporarily crossed from cardiac fatigue into acute cardiac failure.
One of the most interesting findings was the apparent dose-response relationship.
The same athlete tolerated 12 hours with only transient dysfunction. At 24 hours, under similarly high intensity, the system failed. The authors propose that cardiac stress is not determined by duration alone, but by the interaction between duration and sustained intensity. In simple terms: the heart may tolerate long exercise, and it may tolerate high intensity, but sustaining both simultaneously for extreme periods may eventually exceed physiological reserve.
Another major finding involved the right ventricle.
Previous endurance studies already suggested the RV is especially vulnerable during prolonged exercise because pulmonary artery pressures rise substantially during endurance work, while the RV wall is thinner and less equipped to tolerate prolonged pressure overload. This study reinforced that concept. The athlete’s RV dysfunction was consistently worse than the LV dysfunction after both events.
Yet perhaps the most important conclusion is not about damage, but recovery.
Despite developing what objectively resembled acute heart failure, the athlete eventually recovered fully. Biomarkers normalized. Ventricular function returned to baseline. MRI showed no evidence of permanent fibrosis or persistent myocardial injury months later.
That distinction matters enormously.
This paper does not suggest endurance exercise is inherently dangerous. The overwhelming body of evidence still shows endurance training dramatically improves cardiovascular health, longevity, insulin sensitivity, mitochondrial function, metabolic flexibility, and all-cause mortality. The athlete in this paper represents the absolute edge of human performance physiology, not normal athletic practice.
The real lesson is more nuanced:
Human physiology adapts remarkably well to stress, but adaptation still operates within biological limits.
Recovery is not weakness. Recovery is part of the stimulus.
The modern fitness culture often glorifies relentless output, chronic exhaustion, sleep deprivation, and accumulating training load without respecting physiology. This paper argues against that mindset. Even an elite athlete with world-class conditioning eventually reached a threshold where output exceeded recovery capacity in real time.
For most athletes and health-oriented individuals, the practical evidence-based approach is clear:
Build a strong aerobic base.
Train consistently, not heroically.
Use high intensity strategically.
Periodize training loads.
Monitor sleep, HRV, resting heart rate, mood, motivation, and recovery capacity.
Fuel long sessions appropriately.
Reduce training aggressively when systemic fatigue accumulates.
Understand that adaptation occurs during recovery, not during destruction.
The strongest athletes are not the ones who can suffer endlessly.
They are the ones who can apply stress intelligently, recover efficiently, and remain durable for decades.
Nick Krontiris@nick_krontiris
👀
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@lavvspan @PHXCards11 @BOXINGnBBQ Bro that was ai as fuck it uses the whole it’s not x it’s y thing that ai does
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Luis A. Vegas Vicentini retweetledi

Ayer tuve una experiencia EXTRAORDINARIA compartiendo con talentosísimos estudiantes de educación en Harvard, con sus profesores e investigadores.
Todos están emocionados aportando para construir nuestro plan de TRANSFORMACIÓN de la educación en Venezuela!!!
Imagínense, una muchacha de Argentina, junto a uno de Perú, una ex-alumna de la maestría de educación, que es de Indonesia y novia de un venezolano, con tres estudiantes colombianos… Y por supuesto, trabajando con muchísimos venezolanos, dentro y fuera de nuestro país.
Todos debatiendo y diseñando las mejores prácticas de la educación en el mundo, las reformas más exitosas, la utilización de la Inteligencia Artificial para individualizar la enseñanza, la elaboración de los currículos para el mundo de hoy -adaptados a Venezuela-, la intensiva formación y mejor remuneración de los maestros, la creación del Instituto Venezolano de Calidad Educativa para garantizar el desempeño de TODAS las escuelas de Venezuela.
Nuestra Plan de Educación “TODOS A APRENDER” implica llevar a nuestros niños -A TODOS-, a sus aulas de inmediato!
Además, por primera vez en Venezuela, vamos a incorporar los VOUCHERS EDUCATIVOS, para que las familias elijan en cuál escuela -pública, privada, religiosa o comunitaria- quieren que estudien sus hijos.
La Familia ELIGE y el Estado GARANTIZA!
La Libertad requiere de la educación de los ciudadanos. Y nosotros vamos a educarlos a todos para la Libertad!
Gracias a Emiliana Vegas (@EmiVegasV), por su visión, talento, liderazgo y amor por Venezuela, por liderar este increíble equipo, a @Harvard y a todos los estudiantes, maestros e investigadores que lo integran!!
Vídeo completo:
youtu.be/hfecJhvH4hM?is…

YouTube
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@BoxingKingdom14 @Top_BoxingNews Love to try that hydration vest on my next trail run 🙃
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First look at Canelo Alvarez back in training as he gears up for his future bout with Christian Mbilli.
[📹 @Top_BoxingNews]
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