Steve F

Become the dataset you wish to propagate through the universe

@bryan_johnson 10/10

guys you’ll never believe where I found the fountain of youth

@karpathy @Douglance @jenzhuscott What would you use your LLM simulation for?

@Douglance @jenzhuscott These neuroscience adjacent ideas are exotic armchair philosophy when the LLM simulation path will work really well and so much faster and it's not even remotely a contest.

As I build my own 2nd brain 🧠 on Obsidian using @karpathy ‘s wiki idea, it suddenly dawned on me - one day when we r gone, our kids could inherit an interactive map to your mind, passion, obsessions, work, fascinations… It’s kind of beautiful way to think abt your 2nd 🧠.

@bryan_johnson What about measuring HSP activation directly?

If you’re wondering how I initially landed at 20 minutes at 200°F for a daily dry sauna, this protocol is supported by both large observational longitudinal cohorts and smaller interventional studies. These studies demonstrate significant benefits for longevity and healthspan, including reduced mortality and morbidity from all-cause and chronic diseases. Observational evidence suggests that using a dry sauna 4 to 7 times per week for more than 19 minutes per session at temperatures between 176F and 212F provides the highest level of health benefits. Here are some examples of the benefits (using comparable protocols to mine): > 14-40% reduction in all-cause mortality in middle aged men > 48-70% long-term reduction in fatal heart disease in both women and men > 47% Reduction in the risk of developing a high blood pressure in healthy men > 31% average reduction in hsCRP in healthy middle aged men. > 40% Long term sauna use was correlated with decreased all-cause mortality > 48% reduction in dementia risk. > Slightly improved well being, 83% reported better sleep, and 77% less risk of psychotic disorders. Important points to keep in mind While most dry sauna studies do not identify heat-shock response including HSPs, the ones that do only give directional hints of HSPs secretion, to our awareness intracellular expression of HSPs has not been addressed with dry and why I decided to start quantifying my heat shock protein secretion and expression myself. While HSPs are a major driver of sauna benefits, other mechanisms including increased cardiac output and blood flow (exercise mimetic), vascular remodelling and adaptation, as well as sweating all contribute to the benefits.  A strong hit at this are the smaller yet significant benefits observed even with shorter durations and lower frequencies (10–19 minutes, 2–3 times per week), conditions very unlikely to achieve any measurable heat shock protein response. Therefore, do not be discouraged if you aren't ready for the long sessions required for measurable HSP activation. Real health benefits begin with just 10 minutes at 176°F, twice a week. If you are just starting your sauna protocol, remember that reaching longer sessions (over 33 minutes) at extreme heat of 190°F or above requires time. Listen to your body, and progress gradually and be careful not to exceed your personal heat tolerance limits. Also, stay hydrated and if you’re a man, ice your boys. My benefits from my starting protocol were real and persistent over 232 sessions including > 10+ years reduction of my vascular age and functional improvement (central pressure markers showing increased vascular elasticity and compliance) > Full detoxification of 3 out of 6 environmental toxins, remaining 3 were slashed by 55% to 65%, one toxin was reduced by only 15% and persisted at a slightly elevated level (with 15 sessions only). > Elimination of 85% microplastics from my blood and semen > Fertility markers at all time high (count, motility, and morphology) in 24 iced sessions.

I think I need to be fired. I've done 232 dry sauna sessions. Last week I confirmed, for the first time (by swallowing a pill), whether the core temperature threshold that gates the primary cellular repair mechanism was actually being reached in my protocol. The threshold is 102.2°F (39.0°C). For me, that takes 33 min at 195°F. With ice on face and neck, 38min. My standard daily protocol was 20 minutes. That wasn’t enough time to get my core body temp to the heat shock threshold of 102.2°F (39.0°C). Causing me to ask, did I just waste 77 hours and 20 min? It's possible my heat threshold has increased and the heat shock protein release was happening previously, but I doubt it based upon the subjective feeling I now understand as being 102.2F (39.0°C). It’s brutal. For these 232 sessions, I measured the temperature of the air, humidity, duration, frequency, the sweat output, blood biomarkers, vascular response, toxin clearance and fertility markers. There is no human body in history that has been more measured in sauna than mine. Nevertheless, I did not confirm the one number that determines whether the primary mechanism was activating. My goal wasn't to be a sauna bro. It was to saunamaxx. I was doing the former while thinking I was doing the latter. I rest my case. I should probably be fired.

@elonmusk @mitchdeg x.com/stevekfrey/sta…

@mitchdeg It’s a big deal

This presentation from Elon Musk may well be the most consequential in all of history.

history will probably look back to now and say Elon hadn't started his most important organization yet

@AnjneyMidha How will procurement work exactly?

you should be able to just think things and they happen

time for a Siri that works x.com/divgarg/status…

“Since men love freedom, and the freedom of individuals in society requires some regulation of conduct, the first condition of freedom is its limitation; make it absolute and it dies in chaos.” - Lessons of History

This is the first agent to pass human performance at taking actions on the computer on OSWorld

Levels of intelligent tools: 1. A tool that you need to learn how to use (most products) 2. A tool that shows how to use itself (well-designed UX) 3. A tool that proactively understands your goals and uses itself for you (well-designed AI)

The bottleneck is courage

Replace all desires with a single desire.

🚀 INTRODUCING REAL Bench: Our New Standard for Web AI Agent Evaluation We're thrilled to announce the release of REAL Bench - our groundbreaking benchmark to transform how web AI agents are evaluated! Why we created REAL Bench: ✅ We built functional replicas of popular websites to test what agents can REALLY do ✅ We wanted to measure ACTUAL performance, not academic abstractions ✅ We compared leading frameworks including BrowserUse (31%) and StageHand (19%) What web tasks would YOU like to see AI agents tackle? Join our community to be part of the agentic revolution reshaping AI! ⚡ 👉 Explore REAL Bench → [realevals.xyz] 🛠️ Try REAL Bench and get your REAL score today → [github.com/agi-inc/agisdk]

@deedydas MCP servers could exchange recommended UI components to display their results. More composability. Who’s working on this?

New skill unlocked! "Claude, write me an interactive React artifact to help me prep and plan for all my meetings today" Claude Research with the Calendar and Drive integration crushes this and I will be using it every single day.

@PrinceVogel Every time, I come back for more

Being must go crazy. Like absolute god mode

Great scientists can distill what is true in the physical world Great artists can distill what is true in morality and human experience Morality and human experience are seen as subjective, but that's only because the field of neuroscience is so young x.com/stevewattsfrey…

I want to learn physics

To get there it will be helpful to not die today, or tomorrow.... so don't die is a prerequisite that's unlikely to change

My deepest desire isn’t eternal life, it’s closer to boundless creative ability, leading to infinite knowledge