Jane Stinchcombe retweetledi
@AlexanderDent6 These three had to be the stand out papers in immunology for me, barely a single cell in sight: science.org/doi/10.1126/sc…
science.org/doi/10.1126/sc…
nature.com/articles/s4158…
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Jane Stinchcombe
20 posts
Jane Stinchcombe
@StinchcombeJane
Cell biologist/electron microscopist, delighting in the beauty and function of immune cells
University of Cambridge Katılım Kasım 2020
20 Takip Edilen46 Takipçiler
Jane Stinchcombe retweetledi
On #WorldCancerDay we celebrate the researchers at Cambridge and across the world laying the foundations for improved cancer therapies.
Like Professor Gillian Griffiths (KC 1980, and Fellow) and all at the @griffiths_lab
💻bit.ly/KillerTCell
📰bit.ly/GLScienceMay20…
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Jane Stinchcombe retweetledi
Have you checked out the full programme for the #SummerScience exhibtion 2023? With talks, activities, Lates and over three hundred scientists talking about their research, find out more about this celebration of exciting research: royalsociety.org/science-events…
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Jane Stinchcombe retweetledi
New @LabWeekes @TheCIMR research identifies cell surface markers of severe #COVID-19
cimr.cam.ac.uk/research-advan…
Cell Reports@CellReports
Proteomic analysis of circulating immune cells identifies cellular phenotypes associated with COVID-19 severity dlvr.it/SqYQX2
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Jane Stinchcombe retweetledi
NEW Highlight of @ScienceMagazine paper by @StinchcombeJane @griffiths_lab showing that TCR+ ectosomes (green) bud from the surface of a cytotoxic T cell (red) at the immune synapse, which terminates TCR signalling and promotes dissociation from target
bit.ly/3Nw6vJS
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Jane Stinchcombe retweetledi
A new study reveals that cytotoxic T lymphocytes (CTLs) shed activated T cell receptors through ectocytosis, not endocytosis as previously thought. This helps explain how CTLs are able to rapidly destroy multiple target cells in succession. @griffiths_lab
ow.ly/iLNA50OB1qj
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Jane Stinchcombe retweetledi
Ectocytosis renders T cell receptor signaling self-limiting at the immune synapse science.org/doi/10.1126/sc…
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@AnhHLe2702 @AdamRochussen @griffiths_lab @ScienceMagazine @TheCIMR Great questions. Things to further look into.
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@AdamRochussen @griffiths_lab @ScienceMagazine @StinchcombeJane @TheCIMR I see. But do you think cancer cells can increase endocytose to prematurely take away these receptors? Is it possible? This is purely speculation from me.
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Delighted to share our latest research following T cell receptor (TCR) by 3D TEM and showing ectocytosis makes TCR signalling self limiting at the immune synapse.
Many thanks to everyone involved.
@griffiths_lab science.org/doi/10.1126/sc…
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Jane Stinchcombe retweetledi
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Jane Stinchcombe retweetledi
Is the killer T cell the #JohnWick of the immune system?
Cytotoxic T cells are trained assassins who can kill and kill again. Scientists at @griffiths_lab @TheCIMR have captured them on film hunting down and destroying #cancer cells: bit.ly/3mNrFEH
@wellcometrust
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Jane Stinchcombe retweetledi
This week in @ScienceMagazine: @miriamlisci, @griffiths_lab, & colleagues at @TheCIMR, @MRC_MBU, & @dundeeuni
report that mitochondrial translation regulates serial killing by cytotoxic T cells!
bit.ly/Sci_abe9977
#CTLs #mitochondria
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Jane Stinchcombe retweetledi
Such a significant day for #malaria It’s not a perfect vaccine, it’s not the end of the road, but it’s a huge step forward that will save lives. Massive effort by so many people to reach this point. 🎉💯
World Health Organization (WHO)@WHO
A child dies from #malaria every two minutes. One death is one too many. 🚨 Today, WHO recommends RTS,S, a groundbreaking malaria vaccine, to reduce child illness & deaths in areas with moderate and high malaria transmission bit.ly/3iEa4hd #VaccinesWork
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Jane Stinchcombe retweetledi
Sign up for Nature Briefing for the chance to win a 500-piece puzzle that celebrates fifteen groundbreaking female scientists. go.nature.com/3wacsBm
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Jane Stinchcombe retweetledi
What do the primary cilium and immune synapse have in common (except for being two of my favourite things)? Read about it in our perspective for @JCellBiol @griffiths_lab @StinchcombeJane #cilia #immunesynapse #Tcells.
Journal of Cell Biology@JCellBiol
In a new perspective, @tiphainedouanne, @stinchcombejane and @griffiths_lab discuss #cilia and immune #synapses, two distinct biological structures that share common molecular mechanisms bit.ly/3eW8MLW #Immunology #Trafficking
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Jane Stinchcombe retweetledi
In a new perspective, @tiphainedouanne, @stinchcombejane and @griffiths_lab discuss #cilia and immune #synapses, two distinct biological structures that share common molecular mechanisms bit.ly/3eW8MLW
#Immunology #Trafficking
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Jane Stinchcombe retweetledi
Today is #RareDiseaseDay!
There are over 6⃣0⃣0⃣0⃣ rare diseases
🌏 300 million people live with a rare disease accross the world
Rare diseases currently affect 3.5% - 5.9% of the worldwide population👨👩👧👦
Learn more about what is a #raredisease
👉rarediseaseday.org/article/what-i…
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Jane Stinchcombe retweetledi
📢 NEW! The official #RareDiseaseDay video is out NOW
🎉Watch the 6 real life stories and be inspired to join the 2021 campaign.
👥 Share this post with your followers using this hashtag #RareDiseaseDay
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Jane Stinchcombe retweetledi
World View: “If the rich world continues to hoard vaccines, the global pandemic will drag on for perhaps as long as seven more years,” writes @GYamey. go.nature.com/3qVMnDa
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Jane Stinchcombe retweetledi
Congratulations to Colucci and Sharkey groups for their article being featured in Nature Communications Editors’ Highlights “Immunology”! @DrFran_Colucci @Cam_Repro @NatureComms nature.com/ncomms/editors… nature.com/articles/s4146…
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