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i think it is very important to emphasise that if you see people talking about any sort of compounds on X that is their experience with it not trying to discredit anything but it is extremely important to do your own independent research even if you aren’t knowledgeable on the topic having some sort of your own knowledge and opinion on something is better than knowing nothing and just simply trusting others on something if you are going to take it, don’t trust me, don’t trust the biggest accounts on X, or even doctors, you must do your best to understand something other people’s experiences are their experiences yours may be different, doubt everyone and everything if someone has a positive experience see that as a possibility for yourself that may occur after you conduct your own research don’t see anything as fact and please when buying anything ensure the source and purity are top condition these aren’t things you should gamble with, some people will put out information that is truly helpful and some people will put out information that is truly harmful it is up to you to decide what to do with the information

@somaobscura @BasedBiohacker i didn’t get any for myself since i tried injectable epitalon a month or 2 ago and it didn’t do much apart from vivid dreams, i’m 19 so having a fixed circadian rhythm would be counterproductive for me because my sleep timings are very eradic with all the stuff i have to do!!

@supplementmaxer @BasedBiohacker Curious about your thoughts on epitalon

Courtesy of @BasedBiohacker much love, appreciate it very much brother. will report on everything within the next few weeks. a rows of pinealon,epitalon and vilon each are going to my mom and grandfather, most important part of the experiment very excited to see how they benefit from them since they’re much older going to report on that especially.

@arbofdogmas glp1r does too

@supplementmaxer Wdym, it's glucagon agonism that fucks up your sleep

I got off reta because it fucking cooked my sleep and mood, sleep is so much more normal now actually feel restored, praying for the day there’s a GIP/Glucangon only agonist 🙏🙏

@DrCamRx will test it out in the future, thanks for the advice!!

@supplementmaxer Gotta tone down the dosage on Tirz. Less is more.

@BasedBiohacker @CryptosBees always imported it normally from europe

@CryptosBees i'm not aware of any domestic vendors @supplementmaxer what'd you end up doing?

their words, not mine. bromantane BPC ’cured’ ADHD. > bromantane upregulates dopamine > BPC fixed his (probably) nuked gut lining + lowered inflammation and thereby he got all the downstream benefits of neurotransmitter production, mood and ’control’. life is beautiful when you find the right compound for your situation.

@celestialbe1ng @SRD5Alex goal is not to take the drug forever, just for a x amount of time, chronically yes it could be a issue

@supplementmaxer @SRD5Alex Interesting. Isn’t chronically elevated glucagon a terrible idea tho, mostly for the heart?

@DrCamRx will say though, sleep on reta is worse than sleep on triz, both impact it though

@DrCamRx i had worse sleep on triz too, the adhenoia/dysphoria was infact worse on triz compared to reta

i had bad sleep on triz too, not as bad as it was on reta though, triz had significantly more dysphoria/adhenoia for me. the dopamine blunting serotonin promoting effects of glp1r activation in the brain is probably my main issue with these compounds that’s why i feel like i would prefer a gip/glucagon only peptide

@SRD5Alex @supplementmaxer I would imagine this too?

@Razvan1899 @joosrevil i just said it doesn’t

@supplementmaxer @joosrevil But does pregnenolone have the same lowering T effect like u describe progesterone here?

Recently been on a streak of reducing the amount of compounds i take want to reach a normal baseline rather than always experiment will update on my stack in a month or two.

progesterone is suppressive to LH FSH in high doses, (not a issue with 3-6 mg every day or every other day) you’ll just have lower testosterone and hormone production if you take a lot of progesterone without exogenous androgens, pregnenolone doesn’t supress any steroid axis (no suppression of LH FSH) at any dose since it’s the precursor for everything if it suppressed its own synthesis you’d die

@supplementmaxer @joosrevil You think progesterone suppressive. Without androgens what sides you get from progesterone? Dont you get the same sides from pregnenolone Without androgens? Im experimenting with progesterone and dhea but I think the progesterone is having asexual sides unlike preg.

@BerbarianWizard temporarily* if something interesting comes up i’ll give it a shot but i want to normalise my baseline for a bit so i have a better idea of what does what and what’s unnecessary!!

Breaking news: SupplementMaxxer becomes SupplementMinimizer

My best friend’s sister was going through a breakup i asked her if she was in her luteal phase and luckily she was i gave her some progesterone and she was super calm within half an hour. Slowly saving the world !!

@Razvan1899 @joosrevil oral pregnenolone, to some extent pregnenolone covers progesterone’s effects via conversion without suppression, i can’t take too much progesterone as a man when i’m not on exogenous androgens

@supplementmaxer @joosrevil Don't mind if I ask, do you take pregnenolone orally or topically? What about progesterone?

@joosrevil Pregnenolone, bromantane, T3 but i have a fourth which is GH (not peaty but i like running it short term time to time)

@supplementmaxer If you could only use 3 , which would be your too 3 compounds? (Steroids, nootropics, supplements etc.)

@BasedBiohacker thank you for the tip i was just gonna order some, any suggestions for bulk bromantane somewhere else?

@supplementmaxer pglchem bromantane is 💩

anybody got a good source for bulk bromantane powder? 50-100g

@celestialbe1ng your sister’s one of the most beautiful women!!

Copper peptides went viral. But these 3 peptides with twenty (20!) years of human trials behind them didn't. That should bother you. Here's what the current skincare trend skipped... let me actually teach you something. ARGIRELINE — Acetyl Hexapeptide-8 The closest thing to topical Botox that exists — and it hits the exact same target. To fire a muscle, your nerve endings assemble a protein bundle called the SNARE complex and dump acetylcholine across the gap. Argireline mimics the tip of SNAP-25 and jams the assembly. Less neurotransmitter, weaker contraction, softer lines. Topical, reversible, no needle freezing your face. Placebo-controlled trial: fold depth fell 48.9%, against 0% for placebo. Separate study: 30% fewer eye wrinkles in 30 days. THE PENTAPEPTIDE — Palmitoyl Pentapeptide-4 This one is a fragment of collagen itself. When your skin's collagen degrades with age, it sheds these tiny peptide fragments, and your fibroblasts read them as a damage alarm — then start producing fresh collagen to patch the "wound." Pal-KTTKS hijacks that feedback loop: it walks in wearing the costume of collagen breakdown, so your skin ramps up production even though nothing's torn. The fatty-acid tail is bolted on for one reason — to drag a water-loving peptide across your oil-loving barrier. In a double-blind trial: wrinkle depth −18%, wrinkle thickness −37%, skin rigidity −21%. A four-month study on 49 women raised elastin and collagen IV. Published in 2005. MATRIXYL 3000 — Palmitoyl Tripeptide-1 + Palmitoyl Tetrapeptide-7. Tripeptide-1 signals collagen synthesis through TGF-β. Tetrapeptide-7 mops up IL-6, an inflammatory molecule that corrodes your matrix — inflammaging. One rebuilds the house; the other stops the termites. Randomised half-face trial: reduced wrinkle depth, volume and density, smaller area of deep wrinkles. Copper peptides are genuinely brilliant. That was never the argument. Heck, I put them in my product and made them the star of the show for a reason! The argument is that skincare has become a novelty machine: the algorithm rewards whatever's newest, not whatever's most proven — so the molecule with the loudest marketing wins, and the ones with the longest clinical paper trail get buried alive. You're being sold recency. Not necessarily the best most accurate science. The best serum doesn't chase the trending peptide. It runs all of them at once. Save this for the next person waving a $200 copper-peptide-only bottle in your face 💙