
sylvan
422 posts

sylvan
@sylvanprr
Egg Tech @restless_egg | mainly on instagram: sylvanr




(New Essay) VC-Backed Startups are Low Status The traditional VC-backed startup path is becoming low status in the same way investment banking did. An aesthetic collapse across institutions, ideas, and founders paired with the world's tiring of tech has recently accelerated this shift. Some thoughts on the cascade, the generational divide, Anthropic vs. OpenAI, what comes next, and more.









NSF is launching one of the most ambitious experiments in federal science funding in 75 years. The program is called Tech Labs, and the goal is to invest ~$1 billion to seed new institutions of science and technology for the 21st century. Instead of funding projects, the NSF will fund teams. I’m in the @WSJ today with a piece on why this matters (gift link): wsj.com/opinion/scienc… Here’s the basic case: 1) Most federal science funding takes the form of small, incremental, project-based grants to individual scientists at universities. 2) The typical NSF grant is ~$250k/year to a professor with a couple of grad students and modest equipment over a few years. This is a perfectly reasonable way to fund some science, but it's not the only way. 3) A healthy portfolio needs more than one instrument. Project-based grants are like bonds: low-risk, steady, safe. But no one trying to maximize long-run returns would put 70% of their portfolio in bonds. 4) Yet that's basically what our civilian science funding portfolio looks like. Around 3/4ths of NSF and NIH grant funding is project-based. 5) Tech Labs is NSF's attempt to diversify that portfolio. The Tech Labs program is aiming for: - $10-50 million/year awards per team - 5+ year commitments - Measuring impact through advancement up the Tech Readiness Level scale rather than papers published - Up to ~$1 billion for the program - Supporting research orgs outside traditional university structures 6) Scientific production looks very different than it did when the NSF launched 75 years ago. The lone genius at the chalkboard can only do so much. Frontier science + tech today is increasingly team-based, interdisciplinary, and infrastructure-intensive. 7) The team behind AlphaFold just won the Nobel Prize in Chemistry. It came from DeepMind, an AI lab with sustained institutional funding and full-time research teams. It would be near-impossible to fund this kind of work on a 3-year academic grant. 8) Same pattern at the @arcinstitute (8-year appointments, cross-cutting technical support teams) and @HHMIJanelia (massive infrastructure investments to map the complete fly brain). Ambitious science increasingly needs core institutional support, not a series of project grants stapled together. 9) Similarly, Focused Research Organizations (@Convergent_FROs) have showcased a new model supporting teams with concrete missions and predefined milestones to unlock new funding. 10) There’s a whole ecosystem of philanthropically-supported centers doing amazing research, like the Institute for Protein Design, the Allen Institute, the Flatiron Institute, the Whitehead Institute, the Wyss Institute, the Broad — the list goes on. 11) But philanthropy can’t reshape American science alone. The federal government spends close to $200 billion each year on research and development, an order of magnitude more than even the largest foundations. 12) If we want to change how science gets done at scale, federal funding has to evolve. And the NSF and NIH don’t have dedicated funding mechanisms to support or seed these sorts of organizations. 13) Earlier this year, I started working on a related framework called “X-Labs” that built on all this exciting institutional experimentation that’s been happening within the private and philanthropic sectors. It’s time for the federal government to step into the arena: rebuilding.tech/posts/launchin… 14) Traditional university grants are still important for training the next generation of scientists and for certain kinds of curiosity-driven work. But after 75 years of putting nearly everything into one model, we should try something different. 15) And key program details are still being developed! You can reply to the Request for Information with suggestions or feedback on how to design this program here: nsf.gov/news/nsf-annou… 16) Science is supposed to be about experimentation. Science funding should be too.


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Two conversations this weekend make me think that there's a vibe shift afoot in Silicon Valley around what one should work on and what is worthwhile. Culturally, it feels like the moment is ripe for new frameworks: • Davos expert morality is stale and discredited. • It's also apparent that the "just be super based" Counter-Enlightenment is not really an answer. (Yes, woke went too far, but simply inverting it doesn't work.) • EA is no longer the automatic default for smart people. • There's increasing skepticism of slot and slop machine dynamics. Overall, "what is worthy and valuable?" feels like it's becoming more central.

T̶h̶e̶r̶e̶'s̶ ̶a̶n̶ ̶a̶p̶p̶ f̶o̶r̶ t̶h̶̶a̶t̶ There’s an app for you. Meet Wabi: the first personal software platform. Generate beautiful, useful and fun little apps informed by your life.


Restless Egg is offering $50k to be part of a 6-month 10-person cohort of artist-founders building tech products that emerge from their creative experimentation. Apply and build the productive technological intervention you have been aspiring to: apply.restlessegg.com

I need to talk about this. 🚨 Just tried FLORA, and… mind-blowing This isn’t hype This is a total workflow revolution

Disautomatising Technology w/Prof David Bates @BatesW88575 — 12th June, 730pm in the @trust_support space. Organised by Restless Egg. partiful.com/e/JDvLVOMs8gp0…





