zhera

@qqpeepo @Evologixx the bro might be saved

@Evologixx @szeraphn save bro for me

Okay me try this for 30 days. 0 consumed content (unless a tutorial or something educational). Read 1 hour before bed (need suggestions). No food after 6pm (6 hours before bed). The things this old man has to do to try get some quality sleep....

things that helped me the most: - nice cool bedroom - no screens 1h before bed (kindle is ok but orange) - dim room 2h before bed - magnesium glycinate - pitch black bedroom while sleeping - hepa air filter - extremely consistent schedule +-15mins always - go outside and drink water when i wake up - good multivitamin (i like life extension 2perday) also im reading exhalation by ted chiang its very interesting would recommend.

@enyzelo BAHAHAHHAHAHAHAHA

day 1 on adderall

noticed everyones saying take magnesium now without specifying which kind like it doesnt make a difference. best: threonate: brain, memory, cognition glycinate: sleep, anxiety, easy on stomach citrate: cheap, absorbs well, will make you poop worst: oxide: like 4% absorption, basically a laxative sulfate: its epsom salt. for baths. why are you eating this hydroxide: its milk of magnesia bro youre just gonna shit

genuinely insane that creatine has never been tested on alzheimers patients until recently. it worked (20g/day) alz-journals.onlinelibrary.wiley.com/doi/10.1002/tr…

most profound medical discovery

dude thinks removing wisdom teeth that are stuck in your jaw doing nothing is the same as mice losing the molars they actually chew with lmaooo

@CowsEatGrassBlg gag reflex is now a toxicology endpoint apparently

@szeraphn People eat 500g sugar and live. Nobody can even eat 100g shortening without gagging. Sugar wins your own test, bro.

nobody ever acutely overdosed on asbestos either lol

@BasedBiohacker most locked in and focused nootropic user

motherfuckers love to come in and correct me on my tweets where i list the COUNTLESS benefits that modafinil, bromantane, phenylpiracetam etc have with EXTREMELY low downside risk like "ummm... ackchually you can get insomnia and you can disrupt your circadian rhythm. this advice is deadly" motherfucker do you not understand that the only reason we're ingesting this shit is so we can FOCUS EXTREMELY DEEP FOR HOURS ON END in order to make a FUCK TON OF MONEY? i assure you that if you actually put in some work for a day, you would not have insomnia. it does not matter if you took 200 mg at 7 am or 12 pm, you are KNOCKED OUT FROM EXHAUSTION as soon as your head hits the pillow. and even if my circadian rhythm gets a little bit fucked up or i forget to eat lunch because i'm so locked in... i don't GIVE A FUCK???? we are here for RESULTS, not stacking pretty biomarkers and NOT DOING ANYTHING WITH THEM unlike a lot of biohacking mfs, we maintain certain habits and do certain things in order to have more health and energy TO EXPEND what the fuck is the purpose of doing everything right all the time to achieve peak health and vitality only to... do nothing? go to bed at 9 pm wearing fuzzy socks drinking tea with your ugly wife, making $60k a year? THERE IS A REASON behind everything we do when it comes to habit optimization, biohacking, the nootropic stack and it is to MAXIMIZE EFFICIENCY, FOCUS AND RESULTS also, do these people really think that IT'S OVER if you get a headache once, miss a night of sleep on the quest for greatness, miss a meal, feel jaded from ENORMOUS amounts of effort? a lot of people are forgetting that western civilization was built by CHRONICALLY SMOKING ALCOHOLICS who hadn't touched a vegetable or worked out IN 30 YEARS but yes - please tell me about how my cognitive enhancement stack is unhealthy, will ruin my life and brain chemistry meanwhile you're... NOT DOING ANYTHING collecting health stats like pokemon cards, but never using them for anything MOTHERFUCKER there's a solid chance you die 25 years before me just because you got unlucky and got PANCREATIC CANCER. being serious is good TO A POINT but there comes a point where it is absolutely ridiculous. i am going to keep focusing on stacking M's, putting up shots at UNPRECEDENTED SPEED in 12-hour deep work sessions and working like a fucking machine on things i love with HUGE UPSIDE AND MINIMAL SIDE EFFECTS FROM MY PROVEN STACK OF COGNITIVE ENHANCERS. scared losers will continue being scared losers.

both berberine and dhb inhibit complex I. same mechanism. dhb is actually delivering it more efficiently. (turner 2008) metformin blunts vo2max gains 50% and destroys mitochondrial respiration improvements. measured in muscle biopsies and not gut. (konopka 2019) metformin blunts lean mass gains. measured directly in skeletal muscle with increased ampk phosphorylation and suppressed mtorc1. (walton 2019) these effects were observed in muscle. if systemic complex I inhibition is the mechanism, your logic inverts: 100mg dhb produces 7x higher plasma berberine than 500mg oral berberine. higher plasma = more delivery to muscle = more complex I inhibition that actually matters "less gut exposure" is irrelevant if the problem is systemic. moon 2021 actually showed more adverse events with dhb than berberine. (but small n) zero studies on dhb sparing training adaptations exist. youre making efficacy claims the literature doesn't support

DHB does convert to berberine — that’s the point. But the kinetics and distribution are different. DHB produces higher plasma berberine with lower gut exposure, meaning: Less mitochondrial Complex I inhibition in the GI tract Lower AMPK overactivation in muscle (→ fewer training adaptations lost) Far fewer GI side effects (almost zero). Better metabolic effects at lower doses Same molecule downstream, very different pharmacology upstream. Berberine ≠ DHB in practice. That’s why athletes tolerate DHB dramatically better than berberine or metformin.

criticized berberine for complex 1 inhibition then recommended a compound that converts to berberine after absorption. diabetesjournals.org/diabetes/artic…

@cynomel shouldn’t drink one redbull at once

you shouldn’t drink two red bulls at once

@BatmanHealthist tiktok cope.

Aura maxxing starter pack: - Broad shoulders = optimal testosterone - Thick neck = presence - Square jaw = tongue posture - Piercing eyes = mitochondrial health - Deep voice = testosterone - Clear skin = clean liver - Energy = ATP - Calm intensity = balanced dopamine/serotonin

@1thousandfaces_ you know what else loves long telomeres? cancer.

just learned about the peptide epitalon and I would love to learn why not everyone is freaking the fuck out over this

bro really things hrv is useless LMFAO

@CowsEatGrassBlg re read the thead dawg trans fats arent mutagens, dont leave fibers, have massive acute tolerance. still cause heart disease.

@szeraphn Yeah, so what point are you making?

@RayPeatHeadShop something about confusing "cant sleep" with "doesnt need sleep"

Insomnia is inextricably linked to vitality. Ray talked about how people who get on thyroid suddenly need a lot less sleep than is considered ‘normal’. Those of you from UMC homes: I bet your dad slept less than 6-hours a night, and yet maintained a relatively energetic disposition. There are a lot of catabolic processes involved in growth and differentiation: Shedding milk teeth and fat, neural pruning and refinement, bone resorption and remodeling, tumor necrosis, dissolving unstructured collagen, follicular turnover… Very mentally active people tend to be insomniacs. The greatest minds ran on very little sleep. Nabokov, Proust, Mishima, Da Vinki, etc. At some point, if nothing works, you might as well lean into it and drink coffee after dark so you can make the most of your nocturnal hours. No point staying up till 7AM scrolling your cellfone, tossing and turning. What a waste. Take it as a boon and do something meaningful with the extra hours afforded to you. If you’re not up for abstract work then leave the house and experience burning aliveness under the night sky. Choose a pretty star and learn its trajectory so you can navigate the planet by its light.

@lichthauch i refuse to gatekeep knowledge 🤑

Stop explaining yourself. Let them misunderstand. Read by candlelight. Memorize prayers you don't believe yet. Fast until you see clearly. Delete your autobiography. Burn your manifestos. The story you tell about yourself is a cage. Visit graves of people you never met. Learn their names anyway. Sit in empty churches. Silence is older than doctrine. Stop waiting for permission. The elders are dead. You are the elder now. Teach yourself ancient languages. Not for resume. For resurrection. Walk at midnight. Notice what moves in darkness. Befriend it. Your fear is obsolete genetics. Murder it. Stop journaling feelings. Journal prophecies. Then make them true. Find teachers who scare you. If they comfort you they're lying. Comfort is the enemy. Read the texts they banned. Ask why they were banned. The answer is always the same. Learn to fight. Doesn't matter which discipline. A man who cannot defend cannot build. Stop consuming content. Create doctrine. Your doctrine. Forge weapons from your wounds. Every scar is a lesson you paid for in blood. Collect them. The crowd will call you crazy. That's how you know it's working. Find the others. They're looking for you too. Start the monastery. Physical or digital doesn't matter. Build the fortress. Man the walls. Something is coming and the soft will not survive it.