techdiggerk

DeSci has proven it can fund real science. The next bottleneck is adoption: attention → onboarding → retention → revenue. Being a pharmacist + Web3 Growth/BD operator with 8yrs experience and $3.5M in sales, I know a thing or two about generating revenue. I help DeSci projects fix onboarding, incentives, and community quality. If you’re building in DeSci and want adoption (not token hunters/mercenaries), DM me.

Treating neuroinflammatory disease with galectin-3 inhibitors from our GALE project has come one step closer with the discovery of a blood-brain-barrier permeable Galectin-3 inhibitor through AI and animal models by a team from the Fujian Medical University, Fuzhou, China. They demonstrated clear pharmacological and clinically relevant effects in a widely used Alzheimer's Disease model, despite the low potency and limited brain exposure. This is a strong signal ahead of our own experiments.

This is the guy who should have a YouTube channel. I will pay for a subscription to any digital channel he decides to create content on, or for one-to-one tutoring for my kids.

Watch here: youtu.be/ZdXZD_a1p8I

Drug development costs $2.6B and takes 12+ years per drug. Most fail. The business model is cooked. MetaNova is running adversarial drug discovery on Bittensor where miners compete to find better molecules. They're exposing model blind spots that billion-dollar AI labs never publish. Nobody has the incentive to publish bad results. Until now. Their miners want rewards. So they break the models, find the biases, and the whole system gets stronger. Darwinian science with real stakes. New episode of DeSci Pill with @metanova_labs founders Mikayla and Pedro. We go deep on: → Why crypto-native biotech is outpacing trad pharma on speed and cost → Their new nanobody partnership with a Chinese biotech (camels. yes, camels.) → Why cures shouldn't be limited by geography anymore → The case for "vibe coding cures" within 5 years Science needs better incentives. Full stop. Watch the full episode on our YouTube 🤝

Submitted a talk for @EthereumZurich ETH Zurich: DeSci and Translational Neuroscience at Cerebrum DAO. Will cover @Cerebrum_DAO, @BioProtocolEco and many more. @welsharehealth @AxonDAO

Had two final candidates for the same role Candidate A: better technical skills, cleaner code, 6 years at top companies Candidate B: messier code but had relationships with 15+ founders who actually take their calls We hired B AI can clean up code in 30 seconds. It can't get someone to answer your DM. Relationship leverage is the last moat.

Look at the 3 boys from Evergreen school Enugu that topped the Junior Category in South East Maths Olympiad Grand Finale. They have finished engineering maths back to back, finished lacombe back to back, also finished German maths syllabus. They fear nothing in mathematics.

I suddenly remembered when we were doing our MBA and struggling in school, then my classmate’s younger brother—who was a school dropout—showed up with his brand-new car that he had bought. He was making soap and selling it at Oshodi. There was no greater entrepreneurial motivation than that visit. He wished to have what we had, but we knew that all that education was useless without applying it on the streets. That’s why I didn't hesitate to climb tippers with Salil into the Okomu jungle to get work done. Juggling my MBA and running a company came from being even more motivated when I saw a school dropout doing so well for himself, while we couldn't even afford transportation fare to Lagos to attend a tech event. If you truly want to do entrepreneurship the right way, forget your ego and your worries about how you're perceived. Chief Ibru put it even more bluntly to me - “Go and sell fish. Everybody eats fish.”

Aliko Dangote was not the richest Nigerian in 1999. Dangote was not the most connected Nigerian in 1999. I knew him as an importer of rice, sugar, and salt. Dangote simply took the biggest risk: he borrowed, invested in manufacturing, and scaled. Scale is what sets Dangote apart. He doesn’t do small. Dangote went from zero cement plants to become the largest cement operator in Nigeria while WAPCO, CCNN, BCC, and Eagle Cement were all watching. The same with his refinery: he started about a decade ago when NNPC had four refineries and he had zero. Today he has the largest refinery in Africa. Now he has signaled he is going into power, steel, and logistics while the rich and liquid Nigerians are watching him. There is no developed nation without steel, petroleum, logistics, and cement. Dangote is going to own them all. Everyone is watching him. Kudos to Dangote. Give it 10 years, Dangote will break into the top ten globally wealthy persons. I see his strategy as replicating what he has done in Nigeria across Africa. He is building cement, fertilizer, steel, and power plants across the continent. Banks like JP Morgan and Gulf banks are coming to Nigeria to service Dangote. Did you not see the Emir of Qatar introducing Dangote to Trump? Think about it: a foreign president using Dangote as a flex to Trump. If I were a state governor, I would call Dangote, offer zero state and local taxes for 25 years plus free land if he locates heavy industries in my state. (I would even rename a Local Government after Dangote LGA.) I can’t even imagine Nigeria with $80 crude oil without a functional refinery or fertilizer plant. Nigeria needs just two more Dangote's and we are good. If you think I am praising Dangote, you are wrong. You should not think.

If you want to be an innovator, you have to be comfortable looking stupid for a long time. You’re going to piss some people off and you’re going to get a lot of nos. That’s the only way to start having valuable breakthroughs.

At 10, Nigerian 🇳🇬 Genius and Tech Guru, Emmanuella Mayaki was hired as a Coding Instructor by a UK school in 2019 She learnt web design & analysis aged 7. Had diplomas at 9 She's an expert in Java Script, HTML, CSS, JQuery, WordPress, PHP, MySQL, Graphic Design, Python & Java

How to think about the founder who won’t take “No.” for an answer. Regulatory barrier? They find a workaround. Technical limitation? They build around it. Market rejection? They pivot the approach. Funding door slams? They find another way in. Too many investors see this and think, "Difficult. Stubborn. Won't listen." I see it differently, "Problem solver. Unstoppable. Will find a way." The smooth-talking sales founder who charms everyone is often the bigger risk. The enthusiasm and charisma is great for getting funding, but doesn’t always translate to the ability to find their way around barriers. When building a startup, finding ways around barriers is the single most important skill. Don’t give up on the first, “No.” The founder who sees barriers as challenges to overcome... that's who builds something special.

Everything I know about how to run an elite enterprise sales org, I learned from the PTC mafia during my time at Endeca. Cerner used to be PTC for healthtech back in the 2000-2010's - they had a super rigorous sales training program, and you had to be pretty damn good to sell end-to-end EHR to hospitals pre-Meaningful Use (we had some excellent Cerner-trained AEs at Kyruus). Who's the PTC of healthtech today??

This LinkedIn guide is everything you need to land remote, international gigs

Nigerian Medical Doctor, Olawale Ogunlana has been recognized among the top 50 Most Influential Creators on TikTok’s Global Discover List 2026

You see this thing called consistency and relentless audacity? It will get you anywhere you desire. My whole life changed when I embraced these two things.

@brian_armstrong Credentials measure compliance with systems. High agency measures the ability to change them. The people who move the world rarely look perfect on paper. They look restless in environments built for permission.

Some of our best hires were totally unqualified on paper. They always had the same qualities: entrepreneurial, high agency, smart, mission aligned, and they got shit done. If you’re hiring, especially in early stages, seek out & bet on these people. Don’t over-index on resumes.

If you are over 45, you need to watch this video. Especially from 32.30, where he talks about ketones and heart failure. This is where research is important. Had Salil seen this, maybe he would be alive today. These sudden heart problems can happen to anyone. I am getting the L-BHB supplements ASAP. My friend @kenju254, who is much younger than us and very fit, also went into cardiac arrest not long ago, but was extremely lucky. Salil just came back from a one-hour walk, and he was sleeping well. He cleaned out his garage. He died suddenly an hour later, after noticing some early signs, and was being taken to the hospital by his daughter. He was fitter than 99.9% of 54-year-olds. My mother-in-law also went the same way at age 60, without warning. She was a medical doctor and had seen her patients that night, then passed suddenly after a cardiac arrest. She also followed a strict diet and was fit. While a lack of fitness increases the risk tremendously, there is no guarantee it won't happen to you if you don't realize how fragile the body can be and how even minor chemical imbalances can lead to catastrophic effects. Insulin Expert: How To 'Drain' Your Liver of Fat (Do This!) youtu.be/C7LL7VwP8Nc?si… via @YouTube

Education in the era of spatial computers Allowing students to interact with digital content fully immersive in 3D