Fate&Fault Lab

We had the pleasure of hosting Dr. Hao Chang @Hao_UW from @UWMadison at @IGIBSocial, where he shared his fascinating work on frizzled receptors and hair patterning. Our graduate students also got to present their ongoing work and engange in enriching scientific discussions!

Vivek T Natarajan @tnv_lab speaking about "Epigenetic and Stochastic Control of Melanocyte State Dynamics: Implications for Pigmentation, DNA Damage, and Disease" at the 26th International Pigment Cell Conference at @IHCDelhi

Our very talented Jeyashri gave her Pre-Thesis Open Colloquium today at @IGIBSocial. It was really fascinating to hear about Rnasek mediated regulation of neural crest fate specification and how her work unfolded over the years. Congratulations @Jeyashri_Rr!!

@Jeyashri_Rr from our lab will be giving her Pre-thesis open colloquium today on "Rnasek in command: directing neural crest fate specification towards melanocytic identity". Everyone is cordially invited to attend the event at @IGIBSocial Mathura Road Campus Auditorium at 3pm.

Hot off the press: As TB continues to demand long and complex treatment regimens, @VivekRaoigib and his team at @IGIBSocial explored the potential of repurposing sertraline, an FDA-approved antidepressant, as an adjunct to standard TB therapy. The study shows that combining sertraline with frontline TB drugs significantly reduces bacterial burden and improves lung pathology,without compromising the drug pharmacokinetics. Read here: pubs.acs.org/doi/10.1021/ac… Congratulations to the team @KanikaBisht07 @VivekRaoigib @souvik_csir @CSIR_IND

Congratulations @Rakesh_IGIB !!

Warm congratulations to @beena_tweets on her new role as Director of @RGCB_Trivandrum

We aren't just fighting the bacteria; we’re decoding the human response to it. At @IGIBSocial, we turn host-pathogen interactions into blueprints for next-gen TB therapies. Picture credits: @bNikitaa @VaishnaviTr @CSIR_IND @DBTIndia @ANRFIndia @ICMRDELHI @VivekRaoigib @sheetalgandotra @souvik_csir #WorldTBDay #TB #EndTB

Happy to see our lab alumni publishing impactful science! Congratulations Ayush for the publication! Hoping to see many more from you in upcoming years!!

Happy International Women’s Day to all! Sharing a cherished throwback—an author-signed copy of Breaking Through: My Life in Science by Katalin Karikó. A small, but heartfelt reminder to the girls of @IGIBSocial to enjoy doing science, stay curious, and keep believing in the joy of discovery. ✨ #InternationalWomensDay #WomenInScience #InternationalWomensDay #womeninstem @kkariko @souvik_csir @CSIR_IND @CSIR_HRDG

Nature research paper: RYK is a GPNMB receptor that drives MASH go.nature.com/4qIGyHe

“The greatest scientists are artists as well.” — Einstein This week, our young researchers proved exactly that. Swapping pipettes for paint, they turned lab themes into vibrant wall art at @IGIBSocial. Science looks even better when curiosity spills beyond the bench. 🎨🔬✨

Excited to meet the dignitaries and share some of the work from our lab!

Excited to share my PhD work, now out in @eLife! 🐟 We developed a mitfa:Cas9 knock-in zebrafish line for lineage-specific genome editing, enabling in vivo screening for gene function in melanocytes and melanoma cells. Read more here: elifesciences.org/articles/100257

Excited to share our new paper in @Nature, led by @PiotrekPaw_ @KristianaGrigo4 ! 🧬 We developed a new method, ALPACA, to untangle the co-evolution of single nucleotide variants and copy number changes in tumours. Check it out: tinyurl.com/yrppttr3

Such a fascinating study!

New article alert !! In this article, we show that CTNNB1/β-CATENIN function in midline guidance cells is crucial for corpus callosum development. See thread. @shubhatole @AmritaCantSing @MirosevicSpela @IGIBSocial @TIFRScience sciencedirect.com/science/articl…

What causes idiopathic scoliosis? New genetic evidence points to EPHA4, and zebrafish experiments show how disrupting this gene can twist the spine. elifesciences.org/articles/95324… #Genetics #Neuroscience

1/11 Our study on subclonal immune evasion in non-small cell lung cancer has just been published in @Cancer_Cell cell.com/cancer-cell/fu…

People living under polluted skies can rack up DNA mutations that hobble the very genes that protect cells from tumor development. sciencenews.org/article/air-po…