Tulsi Patel

We are excited to share our new publication @NatureComms on discovery and prioritization of therapeutic targets for progressive supranuclear palsy, a devastating #tauopathy. Read news below that links to the paper and our new web app for broad sharing of results.

NYC's Seaport turns purple TONIGHT at 7pm for Alzheimer's disease awareness! Help us reach our $1m fundraising goal by signing up for the Manhattan Walk to End Alzheimer's on Saturday Oct 21st or donating below @ALZNYCC1 act.alz.org/site/TR/Walk20…

Was great to participate in the Walk to End Alzheimer’s with the @IcahnMountSinai #GoateLab team! 💜🧠

@lopeskp Love this energy 🙌🏽

@Juditperala @BBRFoundation Congratulations!! 🥳

Team #GoateLab 🧬🧠 Great time at #GRC Neurobiology of Brain Disorders 🔬🧫#AlisonGoate @tulsi92 @CarmenRomM

'17q21.31 sub-haplotypes underlying H1-associated risk for #ParkinsonDisease are associated with LRRC37A/2 expression in #astrocytes' Kathryn Bowles, Alison Goate, John Crary, @towfiqueRaj @tulsi92 @IcahnMountSinai @SinaiGenetics @karchlab @ZivGanOr …arneurodegeneration.biomedcentral.com/articles/10.11…

Wait, so gun control laws aren’t going to help prevent shootings but laws against abortion are supposed to stop abortions?

This work was performed in collaboration with @DoctorQMd and @HugoGuerreroLab neurosurgery teams at @MayoClinicNeuro. Thanks to all who contributed @TroyCarnwath @ngut0003 @FQTN @garciaCesar_A @SeizureSurgeon and others! #NETanerLab

Meta-analyses with existing microglial datasets support the emerging microglial immunometabolism pathway as a therapeutic target in aging-related disorders. This study provides a human microglial transcriptome resource and reveals implications of age, sex and APOE genotype.

Integrated bulk and single cell analyses revealed known and novel microglial substates and showed enrichment of age-associated module genes in pro-inflammatory & DAM-like clusters. These harbored neurodegenerative disease risk genes including APOE & PLCG2.

We identified a novel microglial signature, characterized its expression in bulk tissue & single cell microglia transcriptomes. We uncovered co-expression modules associated with age, sex, & APOE4 enriched for lipid and carbohydrate metabolism genes in microglia.

We are excited to share our work exploring the transcriptional landscape of human microglia using bulk and single cell approaches to highlight age, sex and APOE-related immunometabolic pathway perturbations. Led by @tulsi92, now published in Aging Cell bit.ly/3Jla0gO

Thanks @ApoEdscvr for highlighting our work in @AgingCell on human microglia transcriptional landscape by @tulsi92 et al. #NETanerLab @MayoClinicNeuro

@OpenAcademics @ngut0003 you and your hand sanitizer🤣

A traveling scientist😂 #AcademicTwitter

@roydanroy @MachloviSaima 👀

Someone's trying to scam my students into buying gift cards for "me". Unfortunately, they're too smart.

When choosing a research advisor, it's tempting to think about the best day of your career but more important to think about the worst day of your life. When your experiments fail, a paper is rejected, and you have a family emergency, who do you want as your advisor on that day?