Tyler Funnell

For those of you hunting for your next position, please consider applying for a postdoctoral position in our lab. Our science is wild and exciting, and I promise to train and feed (yes, w/free food) you well. It doesn't hurt that we are on a publication hot streak.

Interested in developing biostatistical / machine learning tools with applications in translational cancer microbiome research? I am hiring a postdoctoral scholar @MSKBiostats! Please feel free to DM if you have questions. linkedin.com/posts/teng-fei…

Excited to share our R package for microbiome data analysis, published @CellRepMethods, which makes log-ratio lasso regression more accessible for R users, supporting continuous, binary and survival (competing risks) outcomes. github.com/vdblab/FLORAL doi.org/10.1016/j.crme…

Interested in DNA replication and genomic instability? Our new method PERT identifies S-phase cells and estimates replication timing from single cell whole genome sequencing (scWGS) data with heterogeneous copy number biorxiv.org/content/10.110… 1/10

My new lab at @MSKCancerCenter is recruiting a postdoc and also a computational biologist to work on #microbiome and cancer #immunotherapy. peledlab.org. Postdoc position linked below. compbio position soon. Please reach out. tinyurl.com/3m6vpxzr

My wife, Vicky, made an award-winning & touching short film "Elephant". It's about a jovial old man trying to process his Alzheimer's diagnosis while agonizing over how to protect his love from heartbreak. vimeo.com/389534683 A love story in time for Valentine's Day 🙂

Exciting opportunity for a Data Engineer to join the van den Brink lab at MSKCC and help us understand how gut bacteria affect cancer patients! linkedin.com/jobs/view/2837…

Hey everyone, for something a little different on Black Friday, I'd like to show you a no budget micro-short my wife (I helped a bit) made before the pandemic. She shot it in <4 hours with a couple of talented SAG actors! vimeo.com/506658049 #indiefilm #shortfilm #Filmmaking

Interested in structural variant mutational processes at single genome resolution? latest preprint, product years of hard work, reveals clock-like serrate structural variants. kudos to @tylerfunnell @oflanach , everyone in @sajraparicio & @SohrabShah labs. biorxiv.org/content/10.110…

Excited to share some new work with @sajraparicio, @SohrabShah, and teams where we looked at genomic instability at allele-specific resolution in more than 30,000 single-cell whole genomes 1/11

Evolutionary tracking of cancer haplotypes at single-cell resolution biorxiv.org/cgi/content/sh… #bioRxiv

The impact of mutational processes on structural genomic plasticity in cancer cells biorxiv.org/cgi/content/sh… #bioRxiv

CellAssign from @SohrabShah and @kieranrcampbell uses a probabilistic model to leverage prior knowledge of cell-type marker genes to annotate scRNA-seq data. nature.com/articles/s4159… Read our News & Views on supervised clustering for #SingleCellAnalysis. nature.com/articles/s4159…

Twitter friends: My lab is searching for an eccentric, excited computational postdoc/scientist to lead multimodal (metabolic, immunophenotypic, genetic) analysis in RCC and AML. Job ad coming soon, pls spread the word and come join the vibrant community @CompOncMSK @KidneyCancer

Our method CellAssign for automatically assigning cell types from scRNA-seq data is published today Paper: rdcu.be/bQGtI R package: github.com/irrationone/ce… (1/8)

@nofilmschool Whoops just missed this, any way to still get it?

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Reviewer 2 agreed that the ability to determine structures directly within the cellular environment would "transform structural cell biology" elifesciences.org/articles/32493 #fromthedecisionletter #ResearchAdvance

New from Funnell et al. Integrated structural variation and point mutation signatures in cancer genomes using correlated topic models plos.io/2INiELc Part of our cross journal #MachineLearning in Health and Biomedicine collection collections.plos.org/mlforhealth

A new statistical framework for mutation signature discovery out today: journals.plos.org/ploscompbiol/a… . Fantastic work by @tylerfunnell - integrates multiple mutation types into signature discovery with correlated topic models: relevant to cancers with DNA repair defects.

@ChrisCScott @cancersociety Maybe we should have bottle labels globalnews.ca/news/3944739/w…