Varun Sreenivasan

Interested in interneurons and/or the striatum? Look no further. Here's our latest preprint from the @MarinLab on @biorxivpreprint Input-specific control of interneuron numbers in nascent striatal networks biorxiv.org/content/10.110…

Super happy to see our paper on spindle orientation and cortical mechanics finally out! Thank you to all authors Pierre Bohec, Matt Smith, Emma Ferber, @varunsreeni @ana_lisica @BaumBuzz @GSalbreux and @G_Charras See more here 👇 pnas.org/doi/10.1073/pn… A🧵to follow

🔥🥳Our work is now published in #PLOSBiology: Learning-related congruent and incongruent changes of excitation and inhibition in distinct cortical areas dx.plos.org/10.1371/journa… 🥳🔥

Our latest collaborative preprint is out! We find a surprisingly large number of multi-synaptic boutons in the hippocampus (~ half of all synapses!) with interesting morphological properties and potential roles in network synchrony. Check it out! #MSBs biorxiv.org/content/10.110…

@ZoltanMolnar64 @PharmOxford @OxNeuro @ZoltanMolnar64 Great meeting you and the rest of the lab

Dr Varun Sreenivasan (King's College London) gave an excellent seminar on “Matters of life and death - Rules for the survival and integration of interneurons in the brain” at @PharmOxford. We compared notes on silencing or activating pyramidal neuronal populations in the cortex.

New paper from @varunsreeni @MarinLab and others out now in @PNASNews! Input-specific control of interneuron numbers in nascent striatal networks bit.ly/39higm0

I personally believe that academic twitter is very toxic & negative for incoming PhD students. Let us enjoy this excitement, we are nervous enough as is. Telling us how difficult it is is not helping & surely is not great advice. #AcademicChatter

@RL_Stine Spent some time revisiting my teenage years by browsing through some of my favourite Goosebumps books @blossombookhous

An accurate representation of my thoughts and feelings while using the plot function on MATLAB!

Super happy to share our latest preprint and my post-doctoral work from @G_Charras lab! In collaboration with Pierre Bohec, Matthew Smith, Ana Lisica, Emma Ferber, @varunsreeni, @lab_baum and @GSalbreux. biorxiv.org/content/10.110…

@dav_robbe @FrederikeWinkel @MarinLab These are 32 channel Neuronexus probes.

@varunsreeni @FrederikeWinkel @MarinLab Nice ! with what kind of electrodes ?

Nothing better than seeing spikes on (almost) all of your channels! Striatal recordings with @FrederikeWinkel from @MarinLab

I think I can get some paper out in this journal this year!! :))

Shortest chapter ever in a physics book. From Why String Theory? by Joseph Conlon

My Neurocene essay is out now! Philosophers of science have given us lots of theories of scientific understanding and explanation. Let's build on that rather than trying to reinvent the wheel.

While the final numbers of striatal parvalbumin (PV+) expressing GABAergic interneurons is established by long-range inputs from the neocortex, the final number of cholinergic (ChAT+) interneurons is controlled by local inputs from the striatal medium spiny neurons (3/n)

Interested in interneurons and/or the striatum? Look no further. Here's our latest preprint from the @MarinLab on @biorxivpreprint Input-specific control of interneuron numbers in nascent striatal networks biorxiv.org/content/10.110…

Here, we found that two prominent subtypes of striatal interneurons undergo susbstantial post-natal programmed cell death and the final numbers of these two interneurons are established by two distinct mechanisms (2/n)

Brain function requires appropriate numbers of different neuronal subtypes. This involves a strategy where the brain overproduces neurons and then eliminates a fraction of them to make the final network. But the underlying mechanisms are poorly understood (1/n)