Vikram Kasaragod

Happy to share our paper out in @Nature, which provides insights into activation and inhibition of a subset of extrasynaptic GABA(A) receptors. @PMillerLab @UnivCamPharm @BiocEMcam and Smart Lab @uclnpp nature.com/articles/s4158…

Post-translational modifications confer important functions on peptides and proteins. The Piel lab @ETH_en Zurich and collaborators discovered a new modification resulting in complex, steroid-like amino acids. More: biol.ethz.ch/en/news-and-ev…

Nature research paper: A brain-to-gut signal controls intestinal fat absorption go.nature.com/4d1al7d

Congratulations to all of you guys!! Our article "A brain-to-gut signal controls intestinal fat absorption" has been published online in Nature. nature.com/articles/s4158…

Really cool paper! nature.com/articles/s4158…

@MRC_LMB @immunonoah @UKRI_News @The_MRC Many congratulations!

The molecular diversity of hippocampal regions and strata at synaptic resolution revealed by integrated transcriptomic and proteomic ... biorxiv.org/cgi/content/sh… #biorxiv_neursci

How do different neuronal populations and compartments determine molecular and synaptic diversity? Check out our collaborative effort for parallel transcriptomic and proteomic profiling of the hippocampus! @erin_schuman Lab at @MpiBrain @biorxiv_neursci

How #bacteria subvert the host endoplasmic reticulum to create a vacuolar niche for bacterial survival? The role of outer membrane vesicles, #LPS & #ERphagy receptors in remodelling of #ER. Thx to all for an amazing team work 🫶🙌 biorxiv.org/content/10.110… @biorxiv_cellbio

Visualizing the translation landscape in human cells at high resolution biorxiv.org/cgi/content/sh… #bioRxiv

Our latest paper is out @Nature!! 🧵1/4 By exploiting the genetic identity of premotor neurons in the SC, Self-inactivating Rabies, in vivo ephys and computational modelling, we challenged the current view on sensorimotor alignment. nature.com/articles/s4158… @MRC_LMB @martripodi

Excited to share our recent work on the discovery, characterization, & implementation of a new opioid receptor negative allosteric modulator, out in @Nature today! nature.com/articles/s4158…

For 25 years, the Toll-like Receptor pathway was considered a series of distinct protein complexes that drive inflammation. Today, we report that the entire pathway, from receptor to transcription factor, is executed from within one complex—the myddosome. nature.com/articles/s4158…

Excited to unveil our productive collaboration @lab_baum @RouxLab, featuring 3 co-first authors @diorge_souza, @jespadas91, and @sami_chaaban! Special thanks to @ERR_Moody, Tomo Hatano, and @SPOREMOHAN @tweethinking for their invaluable contributions!

Structural insights into GABAA receptor potentiation by Quaalude | Nat Commun doi.org/10.1038/s41467…

A 96-Well Polyacrylamide Gel for Electrophoresis and Western Blotting biorxiv.org/cgi/content/sh… #bioRxiv

High-res In-situ Structures of Mammalian Respiratory Supercomplexes in Reaction within Native Mitochondria biorxiv.org/content/10.110… Check out my lab's first work on membrane proteins! Yes, we knew nothing about detergent😜, so we directly imaged proteins within native membrane!

The Miller lab is super proud to have published its work on GABA-A receptor α5 selective modulators, in Nature Structural and Molecular Biology! nature.com/articles/s4159…. @NatureSMB @vikrambabu @t_malinauskas @RaduAricescu @UnivCamPharm @BiocEMcam

@SrikkanthBalas1 @NatureSMB Thanks very much!!

Happy to share our latest publication now out in @NatureSMB ! nature.com/articles/s4159…

@john_vini @NatureSMB Thank you!