Will Manidis

ScienceIO has been acquired by Veradigm Together, we are going to build the intelligence provider for the future of healthcare.

The broader truth is that we are banning beauty and wonder from our lives. Have a good Monday.

@HomeadeCheese I did not know this / am not catholic. thank you for that, I assumed that encyclicals would be definitionally ex cathedra but it appears you are correct. thank you!

@WillManidis Papal infallibility applies to statements made _Ex Cathedra_ Ex Cathedra proclamations made by encyclical are rare, and almost certainly not this

@nonmayorpete much in the same way you don’t invest in a venture capital fund to make money you certainly don’t invest in hospitality to make money, fundamentally misunderstanding why people do any of this

Serious question: who’s investing in this type of thing and do they ever make any money?

For Memorial Day, do yourself a favor and take three minutes of your time to listen to this Civil War letter from Maj. Sullivan Ballou to his wife. I just started re-watching the Ken Burns series, which debuted in 1990 to a record-breaking audience of 40 million, for the first time since it originally aired. While I had forgotten all of the specifics of the show over the years, I NEVER forgot this letter or this moment, which closed the first episode. Burns kept a copy of the letter in his wallet for 25 years.

In a previous life, @colossusjeremy was a bomb squad technician in the U.S. Army. From 2014 to 2019, he deployed to five countries in the Middle East and Central Asia. For Memorial Day, he wrote about a soldier who killed himself shortly after their deployment, and a memorial service that became less about the man who died than the people left in the room. There is little that’s redemptive or feel-good in the story, and it has nothing to do with business, investing, or technology. But it will leave you thinking about how often we fail to see a person clearly until it’s too late, and sometimes not even then.

there are basically only two trades; 1. light AGI pilled — the markets are failing to price the incredible productivity gains, margin expansion, etc 2. dark AGI pilled — the markets are failing to price the coming violence, destabilization, currency and nation state effects,etc

"what is the most tax efficient structure to pass along a public book to a person who shows sufficient promise of being my reincarnated self without having to sell or crystalize gains" is a meaningfully good tax question that is probably unsolved still

real compounding has never been tried

@nabeelqu @Chris_arnade In a heartbeat

@Chris_arnade @WillManidis I’d do it

Who want's to do this walk with me and prove to them uppity Europeans that you can walk to World Cup games from Manhattan?

Interesting @DouthatNYT on @nanransohoff's essay, @WillManidis's pieces, and (in passing) the call for New Aesthetics: nytimes.com/2026/05/23/opi….

Antonio Garcias has thirty entities invested in SpaceX. In case you were wondering what truly going long looks like

bro it isn’t generally intelligent bro its only read every book and paper ever written and just making connections between them bro. its only thinking for twenty hours bro it’s just brute force thinking bro. its only solving erdos problems bro it could never be an accountant bro

@lmcorrigan1 there's a rowing essay in my drafts somewhere i need to finish, but one of the most beautiful ways in which rowing is a great instructor for life is how unglamerous progression is want to go fast? more steady state want to be better? do your meters

In rowing, a notoriously grindy sport, performative effort gets you nowhere. People ask "what's the hardest workout"? It's a bad question - no single workout is that hard, but a decade of focus and consistency is. Aristocracy is created from cross-generational consistency as Will outlines nicely here.

@nico_laqua yes i agree with you, there is tremendous value in working hard. its very good. people should work harder. i work very hard, many hours a day, i love it. my argument is that i think its easy to inflate ambition and the performance of ambition.

It’s not about cargo culting, it’s about increasing your surface area for ambition. If you want to do something world historic, something big, then sometimes the symbolism behind actions signifies something - there’s a reason why signs on the side of the building matter, why beauty has value, why symbols predate history. And the symbolism behind going all in, behind doing big things, makes it such that when important decisions arise, when there’s a fork in the road in which one may choose a more defined path with little variance and ensured profit or a path with uncapped upside and more variance that is harder to pull off, the latter is more likely to be chosen. And those small decisions to be more ambitious, to care more, to respond to that annoying customer service question at 2 am even when you don’t want to, compound and in a nonlinear way make an important company, an important outcome, more likely. If you’re doing anything at all, you might as well do it right. Nor if you notice is it prescriptive that one must go all in on startups or anything else, but right now, most young builders are told that it’s morally wrong to go all in, and that deserves pushback, because being a bit more “hardcore” is a valid option that worked for lots of important “founders”, from Hernan Cortes to Napoleon to Bill Gates. Others probably accomplished just as much enjoying leisure, like Carnegie, and that’s great! But shaming those going all in is a symptom of cultural nihilism.

You can run your company taking lots of breaks, “working” from home, showing up 2/3/4/5, however many days per week you want, it’s your company, not mine. Writing a long ass article attacking people who care and push themselves hard to create good products comes from a place of insecurity dressed up as intellectual rigor. Working hard and caring is ok, actually. Maybe you can be a pro athlete going to the gym 1 day per week, maybe you can be the best military general not marching on weekends. But attacking those that go to the gym 6 or 7 days per week because they care and because xyz athlete never worked out and did great comes from a bad place, and is bad for the industry, bad for progress, and bad for the soul. It’s funny how those that don’t push themselves have an absolutely visceral reaction to those that do - I certainly don’t write long articles against working from home or being slothful. Bill Gates was always in the office, and I think Microsoft is pretty cool.

@Beuysaunt @garrytan Wolfgang you’re well read enough go know that there is not virtue without beauty

@garrytan This misunderstands the nature of aristocracy. To be aristocratic didn’t mean one would live lavishly, but virtuously. This is why so many literary, scientific and political achievements in history have come from aristos. The lazy aristo is a modern cliche

I like this essay and hope we can both work hard on things we care about AND live good lives where we enjoy good and beautiful things: food, experiences, being real with one another It’s not grindslop vs aristocratic malaise. This is a false dichotomy.

@austin_rief @Emily_Sundberg this chart is missing a big one

When people ask me why we sold Morning Brew, I just show them this chart.

@mattripkey They’re pacs

@WillManidis TP52 but otherwise 💯

@mattarderne harry is a good guy, this isn’t an inditement of him, just a useful example of a trap we can all fall into