Xiaozhou Ye

New paper out in @ISMEJ! Microbes can "remember" their past by modifying their environment. This externalized memory can impact future interactions and community assemblies. academic.oup.com/ismej/advance-… @gajrani_shubham @xiaozhou_ye

How invasion is resisted by microbial communities? Hint - it is cooler than you think. Check out our new paper ! With @xiaozhou_ye and @cratzke1 (Nature Communications): nature.com/articles/s4146… 🧐

As for the pickles? Salt and sealing didn't work long-term. In the end I tried adding more sugar, hoping Lactobacillus would turn it into acid and resist others with the low pH. Result: the contamination never comes back - first application of our work! 9/9

allowing us to leverage the resistance of native microbes to fight/utilize invasion, and even guide rational design of microbial communities to block harmful microbes or to help beneficial ones to settle in. 8/9

Invading microbes bother us in many ways: bacterial infection, cross-contamination in the lab, spoiled food... Our new paper with @cratzke1 @orshalevsk in @NatureComms (rdcu.be/ejxQu) can help us fight microbial invasion more efficiently 1/9

New paper out in Nature Communications Microbial communities shape invasion dynamics in complex but predictable ways. This highlights the need to consider microbial interactions for controlling invasions. Read here: nature.com/articles/s4146… #MicrobialEcology #SystemBiology

We got a preprint out on biorxiv: “Environment-mediated interactions cause an externalized and collective memory in microbes”. biorxiv.org/content/10.110… 1/5

We developed an imaging-free spatial genomics technology where DNA barcodes diffuse to connect locally. Using UMAP, we reconstructed the physical locations of these barcodes, transforming spatial transcriptomics into purely molecular biology. biorxiv.org/content/10.110…

New in @ScienceMagazine with @jaegc. A combinatorially complete fitness landscape with >260.000 E.coli genotypes shows unexpected 🤯 properties. Despite ~500 fitness peaks in this landscape, adaptive evolution can easily navigate to highest fitness peaks science.org/doi/10.1126/sc…

Find this quite cool, screening random genes for function. Turns out like many other things, a quick fix is relatively easy, a specific fix much harder - only 1 in 1e8! Also showed the mechanism by impressive experiments.

Can we witness evolution’s unit shifting from individual to collective, in real-time? @ozan_g_b @wc_ratcliff @YunkerLab evolved large multicellular yeast and said YES! Great fun to spotlight this cool project & its first findings with @orshalevsk @cratzke1. @Trends_Ecol_Evo

A new paper from our lab is out today after peer review: science.org/doi/10.1126/sc…