@Atibento_216 @Zygomatic03 no it does not work, you can only weaken your vessels and basically break your dick; it's much more productive to do NO-maxxing, not only dick will benefit but whole circulatory system as well
English
xo jig
22 posts
@xojigsx @Zygomatic03 Ça marche même après la puberté ? Genre y’aura des résultats visibles même apres ?
Français
@Helios_Movement You missed Polisorb, which works better than any on the list you have - you can also use it preemptively (allergies etc.)
English
Binders are the biohacking tools of Soviet astronauts, Chernobyl survivors and farmers 👇
In general, if you:
-Have been exposed to mold/mycotoxins and heavy metals
-Are struggling with brain fog, fatigue, skin issues or gut issues (especially any form of IBS)
-Plan to use antibiotics/antifungals
then binders are a cheap no-brainer worth looking into.
Binders were popularized for agricultural practices when farmers noticed their livestock were getting sick from eating moldy grains (for example, in 1960 in the UK, 100,000 turkeys died from aflatoxin B1) where adding bentonite clay or activated charcoal (small amounts like 0.5%) to the feed reversed it by trapping mycotoxins inside the gut before they were absorbed into the bloodstream.
Bentonite’s interlayer spacing (1-2 nm) for example intercalates AFB1 molecules through van der Waals forces and hydrogen bonding, reducing bioavailability 85-95%.
In the meantime, Vladimir Nikolaev and his colleagues in the 1980s started using enterosgel, then clays started to get used in Ghana since AFB1 was contaminating up to 70% of maize and was causing cancer in children and now in 2025, it’s quite common to use binders in medical settings.
But what exactly is a binder?
A binder is a substance that grabs onto toxins in the GI tract, locking them up so they are excreted through stool instead of being reabsorbed through the liver-gut cycle(*).
(*) Bile to the intestine to reabsorption and back to the liver.
This process is called enterohepatic recirculation and it is one of the main reasons people stay sick even after removing the source of the toxin.
Bile carries conjugated toxins (in phase II liver detox that adds glucuronide/sulfate groups) -> 95% reabsorbs in the ileum via transporters like ASBT.
Binders stop that loop/reduce reabsorption.
So think of a binder as a toxin sponge inside your gut whose porous surfaces create binding sites through physical forces (van der Waals, ionic exchange) or chemical affinities (hydrophobic interactions for lipophilic toxins).
In medical terms, they’re classified by capacity (mg toxin/g binder) and selectivity (Kd dissociation constants).
Now even though binders do not pull toxins out of your cells or tissues, they are quite useful tools.
But most people add them into their detox routine without understanding what they actually do.
Now of course, the OTC binders that we will talk about usually stop Herx/die off reactions (mobilized toxins with nowhere to go).
Let’s say that you use antimicrobials for SIBO for example, once pathogens begin to die, they release LPS/endotoxins and stored toxins.
Binders pull these and ramp up their excretion.
But what a lot of people do is they use high doses of binders without even working on the drainage pathways (bowels, lymph, kidneys, sweat) first and this combination can 100% lead to a Herx reaction as well.
So before jumping into binders:
1. Work on the drainage pathways first (bowel regularity, bile flow, lymph, hydration).
2. Replenish nutrients (B vitamins, minerals (trace minerals as well) etc)
3. Support phases III->II->I of the liver.
4. Treat dysbiosis to a basic degree if present.
5. Lower the toxin burden by avoiding the main sources of toxins in your environment and using the IR sauna (if possible).
Now let’s talk about some specific binders and what toxins they bind.
Number 1: Activated charcoal (AC).
This one binds LPS/plenty of bacteria metabolites, aflatoxin B1, ochratoxin A, zearalenone, some pesticides like glyphosate and drugs such as acetaminophen.
Upsides: Very effective, usually cheap, broad effects.
Downsides: Will cause constipation to a lot of people who haven’t resolved dysbiosis, traps plenty of fatty acids and minerals as well, needs to be taken 2 hours before a meal or medication.
Number 2: Modified citrus pectin (MCP).
This one greatly binds lead, arsenic, cadmium and galectin-3.
Upsides: Quite effective for these heavy metals (in a study down in 111 kids, when used for 4 weeks it helped drop lead by something like 70%), interesting effects on some cancer types.
Downsides: Expensive, can’t be used before resolving a pathogen overgrowth to a great extent.
Number 3: Cholestyramine (CSM)/colesevelam.
These are just mentioned because they are advocated in the shoemaker protocol (at least they were the last time i checked).
It can help with lipophilic toxins/mycotoxins (the quaternary ammonium groups exchange Cl⁻ for bile acids) but they cause constipation in a lot of people, you need a prescription and in the long run they trap a lot of fatty acids as well.
Number 4: Bentonite clay.
This one binds AFB1, ochratoxin, zearalenone, fumonisin and some heavy metals (Pb/Cd).
Upsides: Cheap, gentle on the gut, broad effects.
Downsides: Plenty are contaminated with heavy metals, can cause constiptation.
Number 5: Micronized zeolite.
This one is great for binding ammonium, lead, cadmium, aluminum, cesium and some aflatoxins.
Upsides: The best binder for UREA cycle issues, great for cadmium, low constipation risk.
Downsides: Plenty are contaminated, can be expensive.
Number 6: Chlorella.
This algae is a good general addition for heavy metals like mercury/lead/arsenic and some dioxins/PCBs.
Upsides: Relatively cheap and safe.
Downsides: Not that effective for severe cases.
Number 7:Humic and fulvic acids.
These are the go to for herbicides such as glyphosate but also pesticides.
They can also be used for chromium toxicity.
Upsides: The safest OTC ones for herbicides and pesticides, fulvic acid is also great for mitochondrial health.
Downsides: Expensive.
Number 8: Enterosgel (there’s also a German one called silicea but it’s derived from silicon dioxide so it’s not the same as enterosgel).
This one is great for binding endotoxins, uremic toxins and bilirubin.
Upsides: Pretty safe and effective for endotoxins and uremic toxins.
Downsides: Doesn’t do much besides this, it has a constipation risk.
That was the 101 but please do not skip the 5 steps that were mentioned before the binders and keep in mind that combination therapy is often needed since each binder has a different affinity profile.
For more on the topic of gut health: fitandball.gumroad.com/l/guthealthms/…
English
@kaaaash____ when to sole purpose of the tech you help develop is to turn user into dopamine zombies (every tech business relies on that - grabbing user attention) - then you start to understand the opposite process is the way to go - no tech and nature
English
then once per couple of days another agent is running proactive architecture evolution that produces design documents that undergo further refinement:
"Mine recent postmortems for repeated failure patterns. Group by layer, name root architecture gaps, propose structural changes, and list bug classes they should eliminate."
English
testing idea for autonomous architect agent in the pirate-architect swe model
vibe-coding takes care of the pirate part, that's clear
but noticed the architect part of swe cycle started taking longer and longer (especially afterr opus 4.6 release)
with gpt 5.5 we are somehow back, but one thing that I noticed is some prod incidents (be it error/warn log events, invariant checks etc.) are permutations of the same issues and not going away
started writing detailed postmortems for every fix that required debugging live prod
error are extracted from loki, vmalert delivers them via webhook that spawns agents which are fixing / writing postmortems with essentially simple prompt:
English
English
@xojigsx @TheDealMakerGuy Not true. Invoices from Google, Cloudflare go to KSeF. So it’s def not only local businesses.
English
You should move to Poland
The gov made everyone “happy” by introducing a central register of e-invoices ”KSeF”
Now when you buy something for your business you just provide your VAT number and invoices get send directly to your special inbox and your accountant has access to it
@levelsio@levelsio
By far THE most annoying part of running a business for me is collecting receipts for my accountant Every month my accountants hounds me for invoices and receipts of every single expense I did, doesn't matter how tiny like $0.50, sometimes also for income (I don't know why) Most companies charge monthly so that means collecting 12 invoices per year at least One reason I am canceling so many SaaS is not even the cost, it's just that I hate bookkeeping so much so I think if I don't spend the money, I don't need to collect invoices and receipts for every single payment every month (also I like extremely high profit margins like 99.99%) I'm down to just about 10 companies I pay now, like Cloudflare, Hetzner, Backblaze etc. so that means only ~120 invoices to collect per year cause most are paid monthly Yes I have an automatic email filter that forwards invoices to my accountant but many companies do NOT send you an automatic invoice by email So you're talking about logging in to 10 websites, them sending you a 2FA code by email, opening your email, entering the code, trying to find wherever the Billing page is hidden, going to Invoices, opening the invoice, clicking Download to DPF (if it even exists) This week I tried to improve this, my accountant uses Xero, so I made a Xero API key, gave it to Claude Code, and asked it to login and figure stuff out, then it just asks me which expenses still need a receipt and a note, I find it and drag the PDF or screenshot into Claude Code and it resolves it Next step is letting it login to all my vendors and also download the invoice by itself which seems very very possible Much easier!
English
@LinusEkenstam This was true maybe 10 years ago. Nowadays exit node location is only 1 out of 10 different techniques employed to build someone shadow profile, and simply going behind the tunnel does not create a new one for you. In other words it simply does not work :)
English
