GI/Liver Path

Can you identify this fascinating creature? 🔬🪱 Hint: It loves guts, sticks to tape, comes out at night, and absolutely does not RSVP. Gender reveal pending…cast your vote 👇 @ParasiteGal #CrittersonTwitter #PathX

Context is everything! Radiation-associated epithelial atypia can be treacherous 😱! Learn the latest from @JBirkness (PMID: 36495943) and other incredible expert pathologists at our 25th Annual Johns Hopkins GI/Liver Pathology CME Course (virtual!) hopkinscme.cloud-cme.com/course/courseo…

🔬 Papillary Fibroelastoma ~ ✴️ "Sea Urchin" #Pathology #Heart #Cardiovacular #CVpath

Unusual case - Colonic glomus tumor !

We think of a "null" (complete loss) p53 immunohistochemical staining pattern in Barrett's esophagus with high-grade dysplasia, but this example of low-grade dysplasia shows it.

55 year-old female, palpable breast mass, ER-, PR-, HER2-, P63- and SMM-.

Fun tip for budding #pathologists! When you see “shredded 🥕 ” (or zucchini or your favorite 🥗) in an esophageal biopsy - take a closer look! Candida loves to lurk around the desquamated debris, often on surface but can be detached too #GIpath Specials in the next tweet

Nasal mucosal mass. Diagnosis? Answer ✅ youtu.be/aT0PaOrx8xc More pics & info: kikoxp.com/posts/5703. Many thanks to @sadiqamer for these incredible images! #pathology #pathologists #pathTwitter #dermpath #dermatology #dermatologia #dermtwitter #ENTpath #microbiology

#Parasite case 781 is up, donated by Dr. Rasool Jafari: Found on skin scrapings. parasitewonders.blogspot.com/2025/07/case-o… is your ID? Answer later this week! #mayopath #pathology #PathBugs

This spectacular metastatic dedifferentiated gastrointestinal stromal tumor to the liver mimics hepatocellular carcinoma.

The answer to the #Parasite Case 778 is now up: Invasive Entamoeba histolytica trophozoites with ingested RBCs. Further description here: parasitewonders.blogspot.com/2025/06/answer… #mayopath #pathology #PathBugs

"Someone has a case of The Mondays." - Amoebas, probably.

Random non-polypoid stomach biopsy. History of colonic inflammatory polyps and recent diarrhea/proctitis from Shigella flexneri. All other infectious workup negative.

For suboptimal biopsies for which a diagnosis of oxyntic gland adenoma is difficult, cyclinD1 can be helpful! PMID: 39863113.#UMiamiPath @ModernPathology

Picture-perfect "onion-skinning" in a case of primary sclerosing cholangitis 🧅 🧅 #pathtwitter #pathx #pathology #liverpath

"Chromosomal Overload" - Mitoses are uncommonly observed in cytopathology of Papillary Thyroid Carcinoma. (FNA)

Another traditional serrated adenoma with ectopic crypt formations (arrow). #UMiamiPath

These two collages display a variety of seeds that pathologists may encounter when examining tissues microscopically. Some of the seeds have a very distinctive appearance permitting their recognition whereas others resemble other seeds, and their origin may be difficult to recognize. They are all in the Atlas of Medical Foreign Bodies (flickr.com/phoytos/foreig…) Collage of 9 images on the left contributed by Dr. PascualMeseguer - @histopatolomon. Collage of 9 images on the right - Images of blueberry and papaya seeds are from Grillo F et al.The Seeds of Doubt: Finding Seeds in Intriguing Places. Front Med (Lausanne). 2021 Apr 14;8:655113. doi: 10.3389/fmed.2021.655113. PMID: 33937291; PMCID: PMC8079647. The other seed images are from Drs. Pascual Meseguer (@histopatolomon), Diego Morales(@DiegoMoralesN), and Abdul Abid (@abdulabidMD).

One could easily mistake these for histiocytes. But what if I told you these findings were associated with a flask-shaped ulcer in the cecum of a patient from Mexico? #microbiology #pathtwitter #pathx #pathology

How to report intestinal metaplasia when you receive specimens labeled as -Distal esophagus: Barrett's esophagus (BE) -Squamocolumnar junction or Z-line: Consistent with Barrett's esophagus if biopsies were taken proximal to Gastroesophageal junction (GEJ) -GEJ: Do not diagnose Barrett's unless you see esophageal ducts or glands (see next post 👇). Say in a comment the differential diagnosis includes BE and intestinal metaplasia of gastric cardia Dr. Bell #CAP24 #pathology #pathologists #PathTwitter #PathX #pathresidents #pathfellow #GIpath