Our news & views article on how cell fates emerge from nuclear architecture through a metabolism-epigenetics mechanism
Nature Metabolism@NatMetabolism
Methylation, acetylation and cell fate dlvr.it/TQcHxX
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Ziwei Dai
73 posts
Ziwei Dai
@ziwei__dai
Assistant professor at Southern University of Science and Technology, China. Interested in studying nutrition, metabolism and epigenetics using mathematics.
People's Republic of China Katılım Nisan 2015
132 Takip Edilen73 Takipçiler
Our recent work on optimal allocation of metabolic enzymes. A mathematically derived principle validated by cross-species omics data
bioRxiv SysBio@biorxiv_sysbio
A universal law of thermodynamics-kinetics coupling shapes enzyme allocation and glycolytic efficiency across species biorxiv.org/content/10.110… #biorxiv_sysbio
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Our algorithm dGbyG for predicting standard Gibbs free energy of metabolic reactions and thermodynamic analysis of genome-scale metabolic networks is now online at Cell Systems: authors.elsevier.com/a/1loAF8YyDfuZ…
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Our work on predicting Gibbs free energy of metabolic reactions and its applications in genome-scale metabolic networks
bioRxiv SysBio@biorxiv_sysbio
Unraveling principles of thermodynamics for genome-scale metabolic networks using graph neural networks biorxiv.org/cgi/content/sh… #biorxiv_sysbio
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Happy to have contributed to this work. Mathematical modeling of transcriptional dynamics in Arabidopsis
genomebiology.biomedcentral.com/articles/10.11…
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Thanks for the invitation. Looking forward to the event
Lei Dai@leidai_CAS
Updated list of confirmed speakers: Terence Hwa Chao Tang Keita Kamino @KeitaKamino Matthew Good @buenoscience Sahand Rahi @sjrahi Steve Presse @LabPresse Andre Levchenko Ziwei Dai @ziwei__dai , SUSTech Zhiyuan Li, PKU Please spread the words to your colleagues and students!
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Thank you for highlighting our work
Agingdoc🩺Dr David Barzilai🔔MD PhD MS MBA DipABLM@agingdoc1
Amino acid variability, tradeoffs and optimality in human diet 🔑"This study may enable the design of human protein quality intake guidelines based on a quantitative framework" @ziwei__dai @LocasaleLab nature.com/articles/s4146… "Amino acid intake is predictive of human health👇
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Ziwei Dai retweetledi
Our study now @biorxivpreprint - algorithms to analyze amino acid composition and intake in human food, dietary patterns (keto, Mediterranean, western etc), and health. Perhaps counter intuitive findings on the nature of protein intake in diet. biorxiv.org/content/10.110…
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Ziwei Dai retweetledi
Amino acid variability, tradeoffs and optimality in human diet biorxiv.org/cgi/content/sh… #biorxiv_sysbio
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Three months since I started my lab at Southern University of Science and Technology, China. Now our lab HPC is finally ready! Also, we are actively recruiting new lab members interested in studying metabolism using computational approaches. Email Ziwei: daizw@sustech.edu.cn
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@FrezzaLab @LocasaleLab Thanks Christian! So happy this one is out 😊
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Congrats @LocasaleLab @cppxmsleepy and co. This is important!
Quantitative Analysis of the Physiological Contributions of Glucose to the TCA Cycle cell.com/cell-metabolis…
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great review from @LocasaleLab and @cppxmsleepy
@doctorconnor check this out
The evolving metabolic landscape of chromatin biology and epigenetics | Nature Reviews Genetics nature.com/articles/s4157…
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Our mathematical model using the concept of cooperativity in quantitative biology to explain the transmission dynamics of COVID-19 and evaluate the efficacy of public health interventions
medRxiv@medrxivpreprint
Cooperative virus propagation underlies COVID-19 transmission dynamics medrxiv.org/cgi/content/sh… #medRxiv
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As someone currently on the job market, I find this article (and the books it cited) very informative and helpful. Fig 2 literally made my day - it was so relieving to see that watching cat videos on YouTube is part of the creative process!
FrezzaLab@FrezzaLab
Very interesting piece on what you need to be a PI: "A major defining quality is relentless perseverance in the face of the odds." This resonates so much, and difficult skills to learn! #PLOSCompBio: Ten Simple Rules to becoming a principal investigator dx.plos.org/10.1371/journa…
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Ziwei Dai retweetledi
NEW Research: Association of sulfur #aminoacid consumption with #cardiometabolic risk factors: Cross-sectional findings from NHANES III
#diet #openaccess
bit.ly/3bF9RoT
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Roses are red
epigenetics is green
I still can’t remember
all these lovely proteins
#academicvalentine
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Glad to have a very small role in this study. Congrats to everyone!
James Krycer@JKrycer
We developed a dynamic flux analysis method to understand how fat cells respond to insulin (@iScience_CP). Driven by Lake-Ee Quek at @CPC_usyd, thanks to an international collaboration between @davidjamesoz, Soga, Kuroda, @LocasaleLab, and @yugism labs.
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Thanks @EACRnews for highlighting our work on the metabolism of single cells in the tumor microenvironment! nature.com/articles/s4146…
EACR@EACRnews
What's new and exciting in the #cancerresearch field? Read the EACR’s latest Top 10 Cancer Research Publications on #TheCancerResearcher magazine: zpr.io/ts2yg
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Exciting work on reconstruction of spatial information from single-cell gene expression data. Can’t wait to apply this to tumor scRNA-seq datasets and see my cat eating the paper: nature.com/articles/s4158…
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