BrentRyanLab

428 posts

BrentRyanLab

BrentRyanLab

@BRyanLab2

Working towards understanding and treating neurodegeneration

Entrou em Aralık 2020
624 Seguindo439 Seguidores
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Anne Hedegaard
Anne Hedegaard@AnneGliaFan·
Our paper on microglial response to, processing and release of tau is finally published! 👩‍🔬 It was a huge collaborative effort and we are proud to see it in the journal Alzheimers and Dementia. There is RNAseq, Cryo-ET, proteomics and more! Do check it out doi.org/10.1002/alz.71…
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Anne Carpenter, PhD
Anne Carpenter, PhD@DrAnneCarpenter·
I'm moving to Purdue University as a tenured professor this summer! Excited to hire postdocs there and get a lab up and running with @wshenrx as co-lead. More details: linkedin.com/posts/annecarp…
Anne Carpenter, PhD@DrAnneCarpenter

I’ve spent 20 years working with mission-driven colleagues at the Broad Institute of MIT and Harvard, at the center of an incredible revolution of computational and molecular technologies. I want to close my time at the Broad with gratitude… Details: linkedin.com/posts/annecarp…

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M W
M W@Michael_E_Ward_·
Excited to share a pre-print from a collaboration between my lab at NIH, Len Petrucelli's lab at University of Miami, and Shyamal Mosalaganti's lab at University of Michigan.
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Emilio Palomares
Emilio Palomares@PalomaresEj·
Writing now a ERC PoC I have some thoughts I would like to share here and open ( why not?) a discussion.👇🏼
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Brian Cox
Brian Cox@ProfBrianCox·
The tragedy of this is that it’s totally unnecessary - I think it’s a result of hasty (to put it politely) decision making at a level below ministers, and therefore will be fixable. But if it’s not fixed quickly the impact will be severe and there will be unpredictable consequences for physics as a whole in the U.K. And that is daft (again, polite language).
Martin Bauer@martinmbauer

UK Science is heading towards a major, major crisis! theguardian.com/science/2026/f…

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Katie Thomas (né Peach) ARUK Thames Valley Network
Katie Thomas (né Peach) ARUK Thames Valley Network@KatietARUKtvn·
🌟Free Oxford lecture: the future of treatments for Alzheimer’s & other neurodegenerative diseases
Sophie L. Farrow@SophieFarrow2

🧠✨ Join us in Oxford for an @ARUKThamesV public lecture — an evening exploring groundbreaking research and future therapies for Neurodegenerative Diseases. 📅 Thu, 16 Oct 2025 | 18:00 🔗 eventbrite.co.uk/e/turning-scie… @ARUKscientist @OxfordDPAG #dementia #research #translation

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Katie Thomas (né Peach) ARUK Thames Valley Network
Katie Thomas (né Peach) ARUK Thames Valley Network@KatietARUKtvn·
Delighted to help create this event! Research is strongest when guided by those it aims to benefit. @AlzResearchUK #PPI #buildingbridges
ARUK Thames Valley Network@ARUKThamesV

Yesterday, we united lab scientists & people with lived experience of dementia in a workshop aimed at building bridges to make research more relevant & impactful. 🧠🔬 @AlzResearchUK @ParkinsonsUK #communication #collaboration

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Dr. Rebecca Wallings
Dr. Rebecca Wallings@RebeccaWallings·
I spy with my little eye something that looks like exhausted microglia 👀👀👀
The Science of Parkinson's@ScienceofPD

Single-cell epigen- & transcript-omic profiling of 3.5M cells from 384 brain samples across 6 regions in 111 #Alzheimers (& control) cases, reveals "widespread epigenome relaxation & brain-region-specific & cell-type-specific epigenomic erosion signatures" cell.com/cell/fulltext/…

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Sophie L. Farrow
Sophie L. Farrow@SophieFarrow2·
A really wonderful evening at our local @PUK_Oxford community meeting hearing from @crassell2 on the politics of research funding and having some great conversations with PwP about the research questions we should be trying to answer! @OxfordPDCentre @ParkinsonsUK
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The Science of Parkinson's
The Science of Parkinson's@ScienceofPD·
New research from the ProtectMove project (n=2364 #Parkinsons & 2909 controls) highlights the importance of copy number variants in PD (particularly in PARKIN) & suggest that rare CNVs in LRRK2 & RAB32 may contribute to disease risk & diagnostic potential nature.com/articles/s4153…
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Raffaele Sarnataro
Raffaele Sarnataro@RafSarnataro·
1/ 🚨 Our new paper is online in @Nature ! As its first author, I’m enthusiastic to finally share it with you all!🎉 🧠 We discovered a mechanistic link between cellular energy metabolism and the control of the need to sleep 💤 👉 nature.com/articles/s4158… @OxfordDPAG 🧵👇
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Michael Lazarou
Michael Lazarou@LazarouLab·
Abstracts close in 48h for the 11th ISA! isa11.org Speaker slots still available including for ECRs and PhD students, as well as poster and speaker prizes!
Michael Lazarou@LazarouLab

ABSTRACTS CLOSE 18 July! The 11th International Symposium on Autophagy 2025 📅 16–20 November 2025 | Lorne, Victoria Registration: isa11.org We have a fantastic line-up of speakers and a wide range of topics focused on the fascinating world of autophagy.

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Laura Winchester
Laura Winchester@Winchy_l·
Excited to see finally see this one in print with all the collaborators from @_neuroproteome. All proteomic data from the publication set and the full consortia (35k samples) also now available on the ADWorkbench nature.com/articles/s4159…
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Hamilton Oh
Hamilton Oh@hammy_oh·
I'm thrilled to share our new study out in @NatureMedicine! We show that a blood test can estimate how aged or youthful one’s organs are and that these organ ages predict future disease and lifespan. Final paper from my PhD in the @wysscoray lab. 🧵1/12 🔗 nature.com/articles/s4159…
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Sophie L. Farrow
Sophie L. Farrow@SophieFarrow2·
Super proud of Libby Cowan for smashing her masters project “Mapping 3D chromatin profiles in sporadic Parkinson’s disease using iPSC-derived microglia” with top marks and being the best student a supervisor could wish for 🌟 we’ll miss you! @OxfordPDCentre @WadeMartinsLab
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