Simon Krauß

Clonal hematopoiesis (CH) is common in older persons without hematologic disease - but what about those who previously had acute myeloid leukemia, and survived the disease? @ScimonkM looked at CH in 373 AML long-term survivors: onlinelibrary.wiley.com/doi/10.1002/he… (1/10)

We are excited to share our latest manuscript on cis-regulatory evolution in primates: biorxiv.org/content/10.110… Congrats to @zkliesmete, @IHellmann and all co-authors! Short summary in a thread below ⬇️

@KlausMetzelerMD 😂

„Let’s aim for Blood, maybe we hit Blood Advances“ 😎 #ASH23

#proudsupervisor #ASH23

Interested in MRD in AML? Stop by at poster #3616 #ASH23 presented by my students Simon Krauß (@ScimonkM) & Tara Holloway. They established a novel NGS MRD assay based on molecular inversion probes & applied it to measure MRD before alloSCT. Postercast: postercast.com/view_postercas…

My first in-person ASH after a 3-year hiatus. Great to be inspired by the atmosphere of innovation, and to connect with colleagues & friends! @tobias_herold @ChrisRauschMUC @ScimonkM #ASH23

This study by @KlausMetzelerMD #MDS23 on ASXL1 mutation VAF in different marrow anatomical sites underscores potential for spatial variation in clonal patterns - echoed in extreme “focal AML” case by @CKBrierley et al @AjHematology 2012 we diagnosed only by sternal aspiration

Is it unavoidable that we all get #clonal #hematopoiesis when aging? #MDS23 #MDSSm #MPNsm #leusm @MDSFoundation

Happy to share my first paper from my doctoral work, a shared effort of Leipzig and Dresden on altered mesenchymal extracellular matrix in MDS. @UwePlatzbecker #Leipzig #Dresden #ECM #MDS frontiersin.org/articles/10.33… #phd #work #share #ECM

@ScimonkM is again looking at AML long-term survivors but from the genetic side. Clonal hematopoiesis is very common in this cohort, but the details matter- e.g. if patients received an allo or chemo only. Have a look at his poster 416!