@GeroScienceAGE Lovely study by a fantastic postdoc Luka Culig continuing our interest in NAD supplementation effects on aging phenotypes!
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Isabel Beerman
133 posts
Isabel Beerman ретвитнул
❗New Open🔓Access Publication
🧪 Nicotinamide riboside treatment enhances stress sensitivity and modulates hematological dynamics in aged mice
👩🔬 By Luka Culig & Isabel Beerman (@BeermanHSCaging) et al.
This study shows that nicotinamide riboside (NR)—a widely studied NAD⁺ precursor—may ⬆️ stress sensitivity and affect 🩸 blood parameters in aged mice, highlighting the importance of context when considering NR as a longevity intervention.
📖 Read the full paper:
↪️rdcu.be/ezguX
#NicotinamideRiboside #NAD #Aging #Stress #Anxiety #Hematology #Geroscience
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@agingdoc1 @hagayanay @GeroScienceAGE Thanks! We were also proud to report a resolution of “conflicting” DNA damage accumulation in HSCs during aging- we show mild proliferation stress can repair accumulated damage- while more extensive proliferation leads to accumulation of damage in HSC!
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Isabel Beerman ретвитнул
DNA methylation drives hematopoietic stem cell aging phenotypes after proliferative stress
@hagayanay, @BeermanHSCaging and coauthors
link.springer.com/article/10.100… | @GeroScienceAGE
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@Pluchinolab @BristenaIonescu @Telencephale @CellStemCell @fossati_v @exosomeguy @Dr_LPJ @dalessandrolab @zarathustra2020 @imohorianu @FrezzaLab Congratulations!!! Love this cover ❤️❤️❤️
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🚀 Excited to see @BristenaIonescu PhD project, with co-first author @Telencephale, featured on the cover of @CellStemCell - Cholesterol-fuelled neurotoxic senescent PMS iNSCs and its pharmacological rescue is a major leap forward! 🎉 (link cell.com/cell-stem-cell…)
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Isabel Beerman ретвитнул
Thrilled to see our hard work on the cover of @CellStemCell! Exploring how cholesterol drives neurotoxicity in PMS iNSCs and showing potential for pharmacological rescue has been an incredible journey. Huge thanks to @Telencephale @Pluchinolab @dalessandrolab & our amazing team.
Pluchino lab - Regenerative Neuroimmunology@Pluchinolab
🚀 Excited to see @BristenaIonescu PhD project, with co-first author @Telencephale, featured on the cover of @CellStemCell - Cholesterol-fuelled neurotoxic senescent PMS iNSCs and its pharmacological rescue is a major leap forward! 🎉 (link cell.com/cell-stem-cell…)
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Delighted to see this fantastic work by @BristenaIonescu @Telencephale now published in @CellStemCell as a joint effort with the @dalessandrolab
#progressiveMS #DrugDiscovery #regenerativeneuroimmunology #MSresearch #stemcells
cell.com/cell-stem-cell…
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Congratulations to @hagayanay a fantastic postdoc on the job market: showed HSC divisional history is tracked by DNA methylation and correlates with function. Also beautifully resolves an outstanding question regarding DNA damage and HSC aging rdcu.be/dW3sC
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Fantastic stem cell aging session closing out 2024 CSH mechanisms of aging conference- HSC biology had amazing representation by Danica Chen, Britta Will (and me!). Thanks to Shin Imai, Will Mair, and Meng Wang for all their hard work organizing this great meeting!
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@TheKingLab @ISEHSociety Congratulations Katherine! ❤️❤️❤️
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Incredibly honored to receive this award from the @ISEHSociety — my scientific family and a community that celebrates respect, inclusion, and collaboration. #iseh2024
Prof Louise Purton@purton_louise
Celebrating Leadership in Diversity, Equity & Inclusivity @ISEHSociety #ISEH2024! Congratulations to @TheKingLab (middle) on being this year’s recipient, so highly deserved 🎉🎉🎉 Who is going to join inaugural recipient @CterminiPhD (left) & myself next year? Photo compulsory 😊
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Isabel Beerman ретвитнул
Don't miss the latest #SimplyBlood 🩸 blog post, featuring the ISEH 2024 Janet Rowley Award Winner, Dr. Robert Signer (@SignerLab). Dr. Signer shares his career path to becoming a PI, mentorship, and more! Read more on simplyblood.org
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Kudos to all the NIA summer interns for their hard work. Very proud of my high school intern Tasnim for earning a poster presentation award- she was a joy to have in the lab and we wish her the best for her Senior year!
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Extremely happy to have been awarded with an ERC Consolidator Grant @ERC_Research - this wouldn’t have been possible without my awesome lab members(past & current!!!:) +the amazing support from the @mpi_ie +more recently the @ETH_en @snf_ch -> stay tuned, the lab is moving ;)
MPI of Immunobiology & Epigenetics@mpi_ie
With #NutriSTEM – we are on the way to the perfect diet for a healthy ageing of stem cells. @maxplanckpress + @ETH researcher @Nina_CabezasW wins an ERC Consolidator Grant. 🥳 🏆#ERCCoG is one of the most competitive funding for researchers in the EU. 👉 ie-freiburg.mpg.de/5856523/2024_0…
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Very happy to have this out! In this study we show that the DNA modification, 5hmC, increases over bodies of tissue-specific genes in the aging liver and serves a function different from DNA methylation. Congrats @occean_james!
nature.com/articles/s4146…
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@IndiraTurney @NIH @NIHAging We are excited to have Dr Turney join the fellow TTIs at the NIA! Welcome Indira ❤️
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🎉BIG NEWS! I'm joining @NIH @NIHAging as an Earl Stadtman Tenure-Track Investigator! Grateful for support from my mentors & network. I'm excited to continue the fight of addressing inequalities in brain aging thru mentorship & research #BHEunit #BlackBrainsMatter #BlackScientist
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