GeroScience

🧬❤️ Longevity and heart health may share a genetic foundation A new study by Pedro Sant’ Anna Barbosa Ferreira and colleagues reports that low genetic risk for coronary artery disease is linked to multigenerational longevity and healthier aging. 💡 The findings highlight the close connection between cardiovascular genetics, resilience, and exceptional lifespan. 🔓 rdcu.be/fkcNp #Aging #Longevity #CardiovascularHealth #HealthyAging #Geroscience

🧪 Can autophagy be exploited to target senescent cells? A new mechanistic study by Matthew Lacey and colleagues used cell painting phenotypic profiling to identify autophagy as a targetable vulnerability in senescent cells, highlighting MCOPPB and related compounds as potential modulators of cellular senescence. 💡 The findings offer new insight into senescence biology and possible therapeutic strategies for healthy aging. 🔓 rdcu.be/fkcKI #Aging #CellularSenescence #Autophagy #Geroscience

📢#CallForPaper📢 Submit your paper focusing on using #companionanimals as models in all aspects of #aging research. ⤵ springer.com/journal/11357/… Read more in the comments! Endorsed by Pumpkin🐾🖤 and Dottie 🐶. #geneticdiversity #environmentalvariation #comparativeepidemiology

📢📢 #CallForPaper 📢📢 The call is still open—don’t miss your chance to contribute! Submit your paper on sarcopenia, muscle loss, frailty, or anabolic resistance today and be part of advancing the science of aging. 💪 📩 Send your manuscript now: 🔗 springer.com/journal/11357/… #aging #sarcopenia #muscleloss #frailty #anabolicresistance #GeroScience #SpringerNature #researchopportunity #submitnow

🧠🩸 Chemotherapy drugs and brain vascular aging A study by Dorina Nagy &Anna Csiszar and colleagues shows that long-term exposure to cyclophosphamide and vincristine may contribute to cerebrovascular damage, including endothelial senescence, impaired DNA repair signaling, and blood–brain barrier dysfunction. 💡 The findings highlight how certain cancer therapies may have lasting effects on vascular and brain aging pathways. 🔓 rdcu.be/fjPV6 #Aging #Neurovascular #Chemotherapy #BrainHealth #Geroscience

🧬 New insights into autoimmunity, aging, and viral biology A study by May A. Beydoun (@MayBaydoun4) and colleagues describes a “telomere–lipid–immunity axis” linking lifelong viral integration (iciHHV-6), telomere length, lipid metabolism, and risk of autoimmune disease. The work suggests that metabolic and telomere-related aging pathways may shape immune responses and influence susceptibility to autoimmunity. 🔓 rdcu.be/fjPQL #Aging #Immunology #Autoimmunity #Geroscience #BiologyOfAging

@JohnGolf_CA Agree—very interesting signal and an important question on intervention. I tried tagging the authors but couldn’t find their accounts unfortunately.

@GeroScienceAGE That is an amazing research finding. Makes absolute sense. I think the link between TB screening immune activation and mortality risk is a huge signal. How do we intervene? Would be interesting to get team to comment.

🦠🩺 Could immune activation predict mortality risk in aging? A new study by Benjamin Seligman and colleagues reports that immune activation detected through M. tuberculosis screening tests is associated with increased mortality risk. The findings suggest that immune system activity captured by routine infectious disease screening may reflect broader biological aging and health vulnerability. 🔓 Read more: rdcu.be/fjqwb #Aging #Immunology #Tuberculosis #HealthyAging #Geroscience

📢 #CallForPapers The Call - “Enhancing #healthspan through #antiaging dietary interventions" - is focusing on the impact of diverse #dietaryinterventions and eating patterns on age-related physiological decline in various organ systems, as well as their role in preventing and treating #AgeRelatedDiseases. Read more in the comments🗯 and submit at the link ⬇ springer.com/journal/11357/… #calorierestriction #alternatedayfasting #timerestrictedfeeding #FastingMimickingDiet

🧠🔬 How do microglia change with age across species? A new study by Laura M. Carr and colleagues characterizes age-related changes in microglial morphology and proliferation across multiple species. The findings highlight conserved patterns of microglial remodeling during aging, offering important insight into neuroinflammation and brain aging biology. 🔓 Read more: rdcu.be/fjqtD #Aging #Microglia #Neuroscience #BrainAging #Geroscience

🏃‍♂️❤️ Cardiorespiratory fitness and vascular aging are closely linked A new 3-year longitudinal study by Vincent Groesser and colleagues shows that declines in cardiorespiratory fitness in healthy older adults are associated with accelerated vascular aging and markers of subclinical atherosclerosis. 💡 The findings reinforce the importance of maintaining physical fitness for cardiovascular health during aging. 🔓 Read more: rdcu.be/fjqsc #Aging #CardiovascularHealth #Fitness #HealthyAging #Geroscience

🦠 Why do older adults respond differently to COVID-19? A new machine-learning study by Tamara Postigo-Casado and colleagues identifies key factors underlying the impaired antiviral response seen in elderly patients with COVID-19. The findings provide new insights into how aging reshapes immune responses and may help guide future strategies to improve resilience against viral infections in older populations. 🔓 Read more: rdcu.be/fjqqq #Aging #COVID19 #Immunology #HealthyAging #Geroscience

Coming to Provo for #AGE2026? 🌄 Bryce Canyon (2hrs). Zion (3hrs). Utah Lake (5 mins). Sundance (30 mins). Science + scenery — the best kind of conference. Explore here: utahvalley.com/things-to-do/ Register → bit.ly/4vDrGxG #AGE2026 #Utah #Provo

10 trainee researchers. 30 minutes. Groundbreaking science. 🧬 Don't miss Trainee Poster Pitches I — June 3 | 11:30 AM | Ballroom A From Alzheimer's resilience to mitophagy & aging — the next gen is ready. 📋 Register: bit.ly/4vDrGxG #AgingResearch #Geroscience

We hosted the 26th BAAM Conference at Buck yesterday, bringing together scientists across institutions to share ideas, spark collaborations, and push the boundaries of aging and metabolism research. Keynotes: Rozalyn Anderson @UWMadison and @wysscoray @Stanford @kapahi_pankaj

@GeroScienceAGE— the official journal of @AmericanAging — publishes the most impactful aging research in the field. Latest: springer.com/geroscience Publication Awards presented at #AGE2026 this June. Register → bit.ly/4vDrGxG #GeroScience #AGE2026 #AgingResearch

🧠💊 Statins and the aging brain — benefit or burden? A new review by Yiwen Liu and Setor K. Kunutsor revisits the complex relationship between statin use and cognitive function in older adults. The article explores current evidence on whether statins may protect brain health, have neutral effects, or contribute to cognitive concerns in aging populations. 🔓 Read more: rdcu.be/fjqoH #Aging #BrainHealth #Statins #Cognition #Geroscience

🩺 Could serine support healthier metabolic aging? A new study by Thomas Olsen and colleagues from The Maastricht Study found that higher plasma serine levels are associated with more favorable metabolic health markers in middle-aged and older adults. 💡 These findings further highlight the potential role of amino acid metabolism in healthy aging and cardiometabolic health. 🔓 Read more: rdcu.be/fjqm7 #Aging #Metabolism #HealthyAging #Geroscience

📢 NEW #CallForPapers focusing on #metabolism, #aging , #pathogenesis, #stress and #smallrnas in C. elegans Read more in the comments and submit 📧at the link⬇️ link.springer.com/journal/11357/… #celegans #agingmodel #DietaryRestriction #mitochondrialfunction #longevity #proteostasis #autophagy #OxidativeStress #MicroRNA