Abha Karki Rajbhandari, PhD

I want to share this research was inspired by me-search: everyday yoga practice that involves breathing and meditation and contemplation to know more biologically!

Organization of neuropeptide systems in the human brain | doi.org/10.1038/s41593… Neuropeptides are functionally diverse signaling molecules in the brain and body. @ericg_ceballos curates an atlas of neuropeptide receptors and relates it to brain function @NatureNeuro 🧩 🧠 ⤵️

JOB ALERT!! We have an opening of a research assistant position in our lab @SinaiBrain for cognitive circuit and behavioral investigation using mouse models. 🐭 See the details below. Looking forward the applications!

The gut can drive age-associated memory loss, research reveals that forgetfulness in later life is not an inevitable biological certainty for everyone. medicalxpress.com/news/2026-03-g…

Harvard scanned meditators' brains and found something that should've made headlines everywhere. 10-20 minutes a day doesn't just "reduce stress," it physically grows new brain tissue, shrinks your fear center, and reverses age-related cortical thinning. Here's the breakdown:🧵

In a 2025 @SciSignal Review, researchers discussed an emerging body of research on the metabolic effects of sleep loss, which disrupts the natural balance of energy within neurons. ⁠ ⁠ The authors highlighted how the loss of sleep forces neurons to shunt resources to cell survival pathways, at the expense of more long-term, energy-demanding processes such as cognition and memory formation.⁠ ⁠ Learn more on #WorldSleepDay: scim.ag/42opuwh

Influenza virus hitches a cellular ride to the heart: Cell Host & Microbe cell.com/cell-host-micr…

Bacteria in our BRAINS?? Surprisingly, we observe translocation of gut bacteria to the brain via the vagus nerve. This occurs in mice fed a high fat diet, or without dietary changes in mouse models of Alzheimer’s, Parkinson’s, and autism. 🧵 biorxiv.org/content/10.110…

Remarkable study from Christoph Thaiss and colleagues demonstrating a lifespan impact of a microbiome-vagal-CNS pathway dysfunction of gut interoception nature.com/articles/s4158…

Another amazing Brain Awareness Week by @SinaiBrain, with our lab members representing the Brain–Body Research Institute and the CEYE program. It is always inspiring to engage with students and the broader community, especially during these difficult times!

HAPPENING NOW at the #FriedmanBrainInstitute Brain Fair! #BrainAwarenessWeek #BrainWeek

Come join us if you live in NY! 👇

We modeled sequential antidepressant treatment in chronically stressed mice to probe the molecular basis of treatment resistance (TRD). 🧵 1/ Read my latest work here! nature.com/articles/s4138…

People living at high altitude have better glucose tolerance & lower diabetes risk, but the mechanism behind why has remained a mystery. New research out in @Cell_Metabolism from @ishahjain's lab reveals an unexpected answer—red blood cells.

In 1921, Otto Loewi had a dream which held the key to a raging scientific debate: is nerve signaling electrical or chemical? He stimulated the vagus nerve of a frog heart in a saline bath: it slowed. Then he transferred some of the bath fluid onto a second, denervated heart in a separate bath, and it also slowed. He had discovered that nerves convert electrical signals into chemical signals. He called the chemical "Vagusstoff," (GREAT name) until it was proved to be a molecule discovered earlier by Henry Dale. Hence, "acetylcholine, the first neurotranbsmitter."

Happy to share a new paper from my lab published in Cell led by Saurabh Yadav. We demonstrate that myocardial infarction (heart attack) is not just a heart injury, it is a distributed neuroimmune disorder. cell.com/cell/fulltext/…

New research reveals that astrocytes—once dismissed as mere "brain glue"—are actually the supervisors. By tuning neuronal activity via calcium waves, they regulate critical states like alertness, sleep, and anxiety. This paradigm shift suggests neuron-only models are insufficient and opens a massive untapped frontier for treating psychiatric disorders. quantamagazine.org/once-thought-t… #Neuroscience #Astrocytes #Brain #BrainResearch #MentalHealth #SciComm

In 1543, Andreas Vesalius published De Humani Corporis Fabrica with detailed drawings of the cranial nerves, including what we now call the vagus nerve. It reminds some of a jellyfish with a big thinking brain ladled over the top....

Join us Feb 24th for this amazing talk! #brainbody

Dr. Sanduk Ruit is a renowned Nepalese ophthalmologist often called the "God of Sight." He pioneered affordable, small-incision cataract surgery techniques and has personally performed or overseen surgeries restoring sight to more than 100,000 people.

The autonomic nervous system plays an important but often underrecognised role in the regulation of glucose and lipid metabolism, contributing to the development of diabetes and obesity. nature.com/articles/s4157…