WalidoNeuroPedia

Gelastic seizures, marked by bouts of uncontrollable laughter, are classically linked to hypothalamic hamartomas. They may also be associated with Pallister-Hall syndrome (caused by a GLI3 mutation on chromosome 7). Present in infancy. EEG often normal due to deep seizure focus. #neurotip #neuropediatrics #epilepsy

@DrADAM34927388 Nothangle = Claude + Benedikt. Bigger lesion including both areas

@NeuroWalid How???

An easy way to differentiate these midbrain syndromes is to remember that, moving from anterior to posterior, all three involve oculomotor nerve damage, with additional distinct features: Weber’s syndrome – affects the anterior midbrain, involving the corticospinal tracts, leading to contralateral weakness. Benedikt’s syndrome – involves the mid-midbrain, including the red nucleus, causing abnormal involuntary movements such as tremor and chorea. Claude’s syndrome – localized to the posterior midbrain, where superior cerebellar peduncle fibers (after decussation) are affected, resulting in cerebellar signs (think Claude = Cerebellar). #Neurotip

Reversal for life-threatening bleeding: #neurotip #stroke

Comparison of primary headaches: #neurotip #headaches

Modifiable risk factors for MS: #neurotip #Multiplesclerosis Credit: continuum.aan.com/doi/10.1212/CO…

Mx criteria for TIA based on the ABCD2 score: #neurotip @stroke

@DrADAM34927388 Simply: Nothangle = Claude + Benedikt.

@NeuroWalid And never foget Nothnagel's syndrome involving the dorsal (tectum) midbrain >>> Ipsilateral 3rd palsy + Ipsilateral cerebellar ataxia ( the opposite fo Claude's)!!!

Stroke Size classification as per ELAN trial:

@BuckBanzai08 Consider not = do not consider. Agree, phrasing issue.

@NeuroWalid Consider not if CAA… dubious phrasing. You would not consider if CAA or if prior hemorrhagic stroke?

When to start anticoagulation after ischemic or hemorrhagic stroke?! #stroke #neurotip

@NeuroWalid This is outdated, especially after multiple trials and the CATALYST meta analysis, which supports early (less than or equal 4 days) in ischemic strokes.

Diagnostic criteria for hereditary hemorrhagic telangiectasias: #neurotip

#bookmark: Clinical and radiologic findings of higher cortical visual disorders. #neurotip #neuroanatomy Made by @neurowalid

🧠 #CARASIL = Cerebral autosomal recessive arteriopathy w/ subcortical infarcts & leukoencephalopathy (HTRA1 gene). 💇‍♂️ Early-onset strokes + alopecia + spondylosis. Neuro: stepwise decline → dementia, spastic gait, mood changes. MRI: WM hyperintensities + lacunes (BG/thalamus), ± microbleeds. #neurotip #stroke