Tenzer Lab
170 posts
Tenzer Lab
@TenzerLab
Focusing on quantitative proteomics using ion mobility and data-independent acquisition techniques
Mainz, Germany Присоединился Aralık 2019
334 Подписки616 Подписчики
New preprint out!
Timsim: a framework to simulate native #timsTOF dda-PASEF and dia-PASEF datasets with full ground-truth annotation, enabling precise benchmarking of #FDR and phosphosite localization errors in #proteomics and #immunopeptidomics workflows. (1/2)
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Our benchmarks reveal inflated true FDR (3–5%) when modified peptidoforms are considered and highlight peak-matching errors in match-between-runs analyses.
Great collaboration with the labs of Andreas Hildebrandt and Mathias Wilhelm. (2/2)
Preprint: researchsquare.com/article/rs-903…
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Tenzer Lab ретвитнул
Big shoutout to @TenzerLab, @DavidGomezZep, and my fantastic colleagues for their support. Learn more about MAETi and stay tuned for the upcoming preprint! (3/3) #TeamMassSpec #immunopeptidomics
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The event was an incredible learning experience in #proteomics while reconnecting with old friends and making new ones in the community. Special thanks to #DGPF and @HUPO_org for supporting my journey with a travel grant. (2/3)
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Thrilled to have shared our latest research on "MAETi: Mild Acid Elution in a Tip enables MS-based immunopeptidomics profiling from as low as 50,000 cells" at #HUPO2024 in Dresden! (1/3)
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A new version 24 of the Human Protein Atlas resource has been released at the HUPO meeting in Dresden, Germany. The data is summarized in eight resources covering different aspects of human protein-coding genes in tissues, cells, cell lines and blood.
proteinatlas.org/news/2024-10-2…
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☹️Google Scholar is a great tool. But it doesn't show how papers are connected with each other.
😀Here's how to fast-track your literature review with a "visual search."
And export your papers to Zotero, Mendeley, or EndNote.
You can learn this workflow in 15 min:
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Follow this excellent tutorial if you want to improve your DDA-PASEF acquisitions with Thunder-DDA-PASEF and ensure high-coverage immunopeptidomics analyses ⬇️
Huge congrats to @TenzerLab @DavidGomezZep and co-authors for this fantastic work recently published in @NatureComms! 👏
DavidGZ@DavidGomezZep
Since it was published 3 weeks ago, I think it's time for a tutorial about leveraging Thunder-DDA-PASEF+MS2Rescore to achieve high-coverage immunopeptidomics on timsTOF instruments. 1/🧵 rdcu.be/dDDyh @NatureComms
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Apply now for the Summer Selection of the International #PhD Program at the German Cancer Research Center, covering all areas of #cancerresearch, including #datascience, #bioinformatics, #epidemiology, #medicalphysics. To apply for your #PhDatDKFZ visit ➡️ t1p.de/3f58d
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Job Alert 🌟 We are recruiting a postdoc in #lcms based #immunopeptidomics in our group @HITRONMainz - position is fully funded for two years. Check the job description and apply here:
jobs.dkfz.de/en/jobs/166492…
Please RT!
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Want to learn how to optimize your #DDA-PASEF acquisition for #immunopeptidomics? Use Thunder-DDA-PASEF! See our paper by @DavidGomezZep from @HITRONMainz: rdcu.be/dA7di
Thanks to a wonderful collaboration with @compomics and @ChristineCARAP1!
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Excellent opportunity to connect to the #immunopeptidomics community and get in touch with the latest developments!
HUPO-HIPP@HippHupo
Save the date! The 3rd HUPO-HIPP summer school. Université de Montréal, Canada August 14th to 16th 2024. @hupo_org #immunopeptidomics #HLA …hipp-summer-school.mailchimpsites.com/application-an…
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@Karl_Mechtler This is a critical and most likely not only theoretical issue. "Sample preparation blank/no cell" SCP samples can reveal unexpected effects.
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With this posting of data that has never been measured, but could exist from our observation, we can show how important it is to measure a "single cell blank".
The experiment should be performed without a single cell, but with identical conditions.
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Congratulations! 👏👏👏
EMBL Events@EMBLEvents
A round of applause for the poster prize winners at #EWCSProteomics 👏 🥇Ericka Itang, @MPI_Biochem 🏅Nawal Hajj Sleiman, @ENSdeLyon 🏅Sophia Müller-Dott, @UniHeidelberg, Heidelberg University Hospital 🏅Joris Frenz, @DKFZ , @KiTZ_HD, @uniklinik_hd ➡️s.embl.org/posterprizespr…
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Last night @EU_YPIC organized a spontanous informal dinner and drinks at the ItPA-HPS-SEPA joint #proteomics congress. Many thanks to Andrea and @TenzerLab for providing drinks! And of course to everyone who attended and made it a great evening!
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@SinzAndrea @dfg_public @UniHalle @unimedizinhalle @IDPseminars @idpsig Congratulations! Well deserved!
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🎉 What a success! We will get funded by the DFG @dfg_public for our #rtg2467 on intrinsically disordered proteins for another 4.5 years!🎉 Thank you, especially our students, for your enthusiasm and great support!😁 @UniHalle @unimedizinhalle @IDPseminars @idpsig
Universität Halle (inaktiv)@UniHalle
Wichtiger Forschungserfolg für die MLU: Die @dfg_public fördert zwei Graduiertenkollegs erneut mit jeweils rund vier Mio. Euro. 🎉 Damit kann die erfolgreiche Ausbildung von Promovierenden in den Bereichen Pflanzen- & Proteinforschung fortgesetzt werden.🔝 mlu.de/9c1uy
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‼️To all junior professors and senior postdocs #teammassspec: if you are doing cool stuff in MS, please apply for the prestigious Mattauch-Herzog award of the German Society for MS 🔽.
Please check here:
DGMS.eu/en/awards-pres…
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@L_Bunse @dgfi_org @Novartis @Platten_lab @platten_michael @UniHeidelberg @DKFZ Congratulations - well deserved!
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Extremely honored to receive this this award for therapy related research from @dgfi_org @Novartis to improve outcomes for glioma patients with combinatorial immunotherapies! Special thanks to my colleagues and friends @Platten_lab @platten_michael @UniHeidelberg @DKFZ
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bruker.com/fr/news-and-ev…
It's quite clear to me now, the future of proteomics on timsTOFs is Slice-PASEF-like and scanning quadrupole methods. We boosted Slice-PASEF performance in recent DIA-NN betas and will improve it further. Scanning support is in works, stay tuned :)
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