CA: A Cancer Journal for Clinicians

New @AmericanCancer report on #ColorectalCancer (CRC) finds that rates are increasing in younger generations, largely by cancers in the distal colon and rectum. Rectal cancer now makes up nearly one third of all CRC diagnoses. acsjournals.onlinelibrary.wiley.com/doi/10.3322/ca… @OncoAlert #CRCSM

ICYMI: CA has published a new phase 3 #ClinicalTrial! Read about ACROSS2, which is distinguished from broader, all‐comers combination trials like FLAURA2 and MARIPOSA. acsjournals.onlinelibrary.wiley.com/doi/full/10.33… @OncoAlert

The number of cancer survivors is rising, and so is the need for focused research. Explore the @AmericanCancer Journals' virtual collection on survivorship research, including statistics, care planning, and long-term outcomes. 🔗 acsjournals.onlinelibrary.wiley.com/doi/toc/10.332… @OncoAlert

#ColorectalCancer incidence and mortality continue to decline in adults ≥65, decreasing by >2% per year. However, rectal cancer incidence increased 1% per year across all ages from 2019–2022, reversing decades of decline. More stats: acsjournals.onlinelibrary.wiley.com/doi/10.3322/ca… @OncoAlert #CRCSM

Many #ColorectalCancer cases and deaths are preventable with screening and access to high-quality treatment. Nearly half of people diagnosed before 50 are ages 45–49 and eligible for screening—yet screening prevalence is just 37%. acsjournals.onlinelibrary.wiley.com/doi/10.3322/ca… @OncoAlert #CRCSM

In case you haven't heard, we recently launched a consolidated presence on Instagram! Follow us at ACSJournals to keep up with highlights and other happenings from the @AmericanCancer family of journals. 📚

Editorial by @kgunturuMD @HinaKhanMD @GlopesMd on targeting tumor suppressor gene co‐mutations in EGFR-mutant nonsmall cell lung cancer. Authors discuss how the ACROSS2 phase 3 trial sharpens the case for early intensification. Read here: acsjournals.onlinelibrary.wiley.com/doi/full/10.33… @OncoAlert

New in CA 📕 Investigators from the ACROSS2 phase 3 trial offer a thoughtfully designed attempt to improve outcomes in advanced EGFR‐mutant #NSCLC with tumor suppressor gene co‐mutations. See the results here: acsjournals.onlinelibrary.wiley.com/doi/full/10.33… @OncoAlert #CancerClinicalTrials

March is #ColorectalCancerAwarenessMonth Our special collection covers the latest #ColorectalCancer research, including diagnosis, risk factors, prevention, and more: ow.ly/5rBp50Yogwj @JournalCancer @CACancerJournal @CancerCytopath @IntJCanc

For #WorldKidneyDay, revisit this #VirtualTumorBoard highlighting a multidisciplinary approach w/ cytoreductive surgery, systemic treatment and genetic evaluation for a young adult patient with metastatic RCC. Patient and caregiver perspective included. acsjournals.onlinelibrary.wiley.com/doi/10.3322/ca…

Rates of #ColorectalCancer are rising in adults under 65, signaling a shift toward younger generations. The findings are revealed in a new @AmericanCancer report published in @CACancerJournal. @ABC summarizes the report here: ow.ly/pmjK50Yrv3g #TrendingResearchTuesday

🌍 ICYMI: New study on global cancer statistics for children by Jianxing He MD et al. By highlighting geographic & socioeconomic disparities of childhood cancer, these findings can inform targeted cancer control strategies on a global scale: acsjournals.onlinelibrary.wiley.com/doi/10.3322/ca… @OncoAlert

During #ColorecalCancerAwarenessMonth, revisit @AmericanCancer research led by @FarhadIslami et al on potentially preventable cancer cases in the US. Approximately 54% of all CRC cases in 2019 were attributed to modifiable risk factors. 🔗 acsjournals.onlinelibrary.wiley.com/doi/10.3322/ca… @OncoAlert

During #ColorecalCancerAwarenessMonth, revisit @AmericanCancer research led by @FarhadIslami et al on potentially preventable cancer cases in the US. Approximately 54% of all CRC cases in 2019 were attributed to modifiable risk factors. 🔗 acsjournals.onlinelibrary.wiley.com/doi/10.3322/ca… @OncoAlert

This edition of "Perspectives: Research in Context" features work published in @NEJM in 2024, which found increased survival with and immunotherapy combination versus chemotherapy for a rare metastatic #ColorectalCancer: acsjournals.onlinelibrary.wiley.com/doi/10.3322/ca… @ben_schlechter @OncoAlert

In honor of #ColorectalCancerAwarenessMonth, access a special collection of #ColorectalCancer research articles from the American Cancer Society Journals. Now included: the @AmericanCancer 2026 Colorectal Cancer Statistics report: acsjournals.onlinelibrary.wiley.com/doi/toc/10.100… @OncoAlert #CRCSM

#ColorectalCancer is the 3rd most common cancer in both men and women in the US and the 2nd leading cause of cancer-related death. For adults under 50, it’s now the No.1 cause of cancer-related mortality. Read the @AmericanCancer report: acsjournals.onlinelibrary.wiley.com/doi/10.3322/ca… @OncoAlert

Genetic and genomic testing holds promise for children with cancer but brings unique ethical and communication challenges. New review by @BrittanyLeeMD @JonMarronMD highlights key considerations and practical guidance for clinicians. acsjournals.onlinelibrary.wiley.com/doi/full/10.33… @OncoAlert #PedOnc

.@AmericanCancer #CervicalCancer screening guideline update allows self-collection of vaginal samples for HPV testing. When self-collected specimens are HPV negative, repeat testing in 3 years is recommended. acsjournals.onlinelibrary.wiley.com/doi/10.3322/ca… @OncoAlert #gyncsm #HPVAwarenessDay

HR+/HER2- metastatic breast cancer is driven by diverse biology & evolving resistance. @DrDebuTripathy et al discuss precision treatment advances through targeted therapies, genomic profiling, & patient-centered decision making: acsjournals.onlinelibrary.wiley.com/doi/10.3322/ca… @OncoAlert #BCSM #TNBCDay

Nearly half of all #ColorectalCancer cases now occur in adults under 65, according to a new @AmericanCancer report published in @CACancerJournal. The findings are covered by @nytimes: ow.ly/WfC550YogTG #TrendingResearchTuesday #ColorectalCancerAwarenessMonth