Prostate Cancer

A student-initiated account to help #ProstateCancer research community on Twitter. Follow this account, and you will be notified on all publication (small or big) related to #prostate #cancer, soon after they appear on #PubMed. Please Like & Retweet to spread the word.

Excited to share our new study in 𝘾𝙖𝙣𝙘𝙚𝙧 𝙍𝙚𝙨𝙚𝙖𝙧𝙘𝙝! We focus on PROX1 as a key driver of neuroendocrine #ProstateCancer and highlight its potential as a therapeutic target. Huge thanks to @mishabeltran for her mentorship! bit.ly/3HRIvAU @PCF_Science @CDMRP

Off-pore nucleoporin sPOM121 transcriptionally propels β-Catenin driven tumor progression and immune escape in prostate cancer. 𝘾𝙖𝙣𝙘𝙚𝙧 𝘿𝙞𝙨𝙘𝙤𝙫. @VRodriguezBravo @DomingoDomenech #ProstateCancer bit.ly/44ZMoww

KMT2C deficiency drives transdifferentiation of double-negative prostate cancer and confer resistance to AR-targeted therapy. 𝘾𝙖𝙣𝙘𝙚𝙧 𝘾𝙚𝙡𝙡. #ProstateCancer cell.com/cancer-cell/ab…

Spatially resolved transcriptomic analysis of the adult human prostate. 𝙉𝙖𝙩 𝙂𝙚𝙣𝙚𝙩. #ProstateCancer nature.com/articles/s4158…

Engineering sonogenetic EchoBack-CAR T cells. 𝘾𝙚𝙡𝙡. #ProstateCancer bit.ly/4ivLpYt

Germline-Somatic Interactions in BRCA-Associated Cancers: Unique Molecular Profiles and Clinical Outcomes Linking ATM to TP53 Synthetic Essentiality. 𝘾𝙡𝙞𝙣 𝘾𝙖𝙣𝙘𝙚𝙧 𝙍𝙚𝙨. #ProstateCancer bit.ly/421SiKR

Emerin Dysregulation Drives the Very-Small-Nuclear Phenotype and Lineage Plasticity that Associates with a Clinically Aggressive Subtype of Prostate Cancer. 𝘾𝙡𝙞𝙣 𝘾𝙖𝙣𝙘𝙚𝙧 𝙍𝙚𝙨. #ProstateCancer bit.ly/4iJ3m6N

Heterogeneous Responses to High-Dose Testosterone in Castration-Resistant Prostate Cancer Tumors with Mixed Rb-Proficient and Rb-Deficient Cells. 𝙈𝙤𝙡 𝘾𝙖𝙣𝙘𝙚𝙧 𝙏𝙝𝙚𝙧. #ProstateCancer bit.ly/4kXKgvj

ETV5 reduces androgen receptor expression and induces neural stem-like properties during neuroendocrine #ProstateCancer development. 𝙋𝙧𝙤𝙘 𝙉𝙖𝙩𝙡 𝘼𝙘𝙖𝙙 𝙎𝙘𝙞. bit.ly/4iO72UY

Tumour-wide RNA splicing aberrations generate actionable public neoantigens. 𝙉𝙖𝙩𝙪𝙧𝙚. #ProstateCancer nature.com/articles/s4158…

Lon protease 1-mediated metabolic reprogramming promotes the progression of prostate cancer. 𝘾𝙚𝙡𝙡 𝘿𝙚𝙖𝙩𝙝 𝘿𝙞𝙨. #ProstateCancer nature.com/articles/s4141…

Assessing the contribution of rare protein-coding germline variants to prostate cancer risk and severity in 37,184 cases. 𝙉𝙖𝙩 𝘾𝙤𝙢𝙢𝙪𝙣. #ProstateCancer nature.com/articles/s4146…

CRISPR screening identifies regulators of enhancer-mediated androgen receptor transcription in advanced prostate cancer. 𝘾𝙚𝙡𝙡 𝙍𝙚𝙥. #ProstateCancer @TakedaDavid bit.ly/3CV4BA0

Targeting ADAR1 with a small molecule for the treatment of prostate cancer. 𝙉𝙖𝙩 𝘾𝙖𝙣𝙘𝙚𝙧. #ProstateCancer nature.com/articles/s4301…

Genome-wide association study of prostate-specific antigen levels in 392,522 men identifies new loci and improves prediction across ancestry groups. 𝙉𝙖𝙩 𝙂𝙚𝙣𝙚𝙩. #ProstateCancer nature.com/articles/s4158…

NXP800 activates the unfolded protein response, altering AR and E2F function to impact castration-resistant prostate cancer growth. 𝘾𝙡𝙞𝙣 𝘾𝙖𝙣𝙘𝙚𝙧 𝙍𝙚𝙨. @AdamSharpMedOnc #ProstateCancer bit.ly/4jsvwUv

AR alterations inform circulating tumor DNA detection in metastatic castration resistant prostate cancer patients. 𝙉𝙖𝙩 𝘾𝙤𝙢𝙢𝙪𝙣. #ProstateCancer nature.com/articles/s4146…

Now online in @CD_AACR: Androgen Receptor Inhibition Increases MHC Class I Expression and Improves Immune Response in #ProstateCancer -by Lisa Chesner, @felixfengmd, @Moran_Lab, and colleagues doi.org/10.1158/2159-8… @UCSFCancer @OHSUKnight

Plasma cell-free DNA chromatin immunoprecipitation profiling depicts phenotypic and clinical heterogeneity in advanced prostate cancer. 𝘾𝙖𝙣𝙘𝙚𝙧 𝙍𝙚𝙨. bit.ly/3VCghxX

Iron-loaded cancer-associated fibroblasts induce immunosuppression in prostate cancer. 𝙉𝙖𝙩 𝘾𝙤𝙢𝙢𝙪𝙣. #ProstateCancer nature.com/articles/s4146…