Cascales Lab

Very happy that our work on the T6SS ADP-ribosylcyclase toxin made the Cover at JBC @jbiolchem ! Congratulations Julius @MartinkusJM for designing this Cover ! @DukasJu @LaurentTerradot

Happy to share the last work of Julius (@MartinkusJM) led by Dukas Jurenas. Poly-immunity arrays associated with Rhs and CDI toxins and linked to a novel genetic element (XPC cassette) confer protection against competitors. @CurrentBiology Kudos !! cell.com/current-biolog…

Happy to share the last paper form the lab: "Specialized shuttle proteins recognize T9SS signals and target effectors to their final destinations". Great work by @maelle_paillat, led by @doan_thierry in collaboration with @StephaneAUDEBE1 @LISM_CNRS_AMU rdcu.be/eP5Xe

Applications closing tonight (midnight French time) !!! Still a few hours to apply !!

Open position to work on Type IX secretion (#T9SS) in our lab, in collaboration withe the group of Eric Reynolds at the Dental School of the University of Melbourne. Please spread the word, and forward to anyone potentially interested ! Apply here: emploi.cnrs.fr/Offres/Doctora…

We will have soon an Open position for a PhD thesis position to work on bacterial secretion systems ! Stay tuned !!

We have an Open position !! Either at the Engineer or post-doctoral level, to work on filamentous phages. Collaboration between @l_houot and @doan_thierry To apply at the E level: emploi.cnrs.fr/Offres/CDD/UMR… To apply at the post-doc level: emploi.cnrs.fr/Offres/CDD/UMR…

This work complements the great work published in July on a T7SS effector with ADP ribose cyclase activity, by Jake Collauti and @JohnWhitneyIIDR. jbc.org/article/S0021-…

Happy to share our work on a T6SS effector with ADP ribose cyclase activity, published in JBC @jbiolchem Great work of Julius Martinkus and (always) great collaboration with Dukas Jurenas and @LaurentTerradot jbc.org/article/S0021-…

📢 Job alert! The Structural Microbiology Laboratory (albesalab.org) has two new openings! We are looking for a PhD student and a Research Technician to join our team. Project: "Structure-function studies of Type VI secretion system toxins". biofisika.org/en/join-us

The application deadline has been extended for a postdoc position in our lab until August 22. Please enquire/apply if you are interested in ADP-ribosylation, ubiquitination, genome stability or immunity. my.corehr.com/pls/uoxrecruit…

We have an open engineer position to work on type IX secretion (T9SS), under the supervision of @doan_thierry (collab with HP Fierobe & A. Tolonen). 1-year contract, renewable up to 3.5 years. Please apply here or forward to anyone potentially interested: emploi.cnrs.fr/Offres/CDD/UMR…

Post-doc fellowship available in my lab at Umeå University, Sweden🇸🇪. The project is focused on structure and function of lipoprotein transports systems in Gram-negative bacteria. Read more and apply here: umustipendie.varbi.com/en/what:job/jo… Closing date - 10th of august 2025.

@JefCavalier @PSantTB @canaanlab @LISM_CNRS_AMU @KremerLaurent1 @MaP_Proteomique @IBMM_Balard Congrats to all !

It is my real pleasure to share our ASAP article published in ACS Infect Dis. Another great collaboration with @PSantTB @canaanlab @LISM_CNRS_AMU @KremerLaurent1 @MaP_Proteomique @IBMM_Balard and more... pubs.acs.org/doi/10.1021/ac…

Le LISM (lism.imm.cnrs.fr) propose une mobilité NOEMI pour travailler sur des assemblages de l'enveloppe bactérienne. Profil microbiologie, bio mol, avec une envie de faire de la biochimie, de la microscopie ou de la bio cell ! Rejoignez une unité dynamique !!

We moved to BlueSky. Please join us and follow us there ! cascaleslab.bsky.social

@skykk_1000 Yes !

@CascalesLab Is this position open for international candidates?

We have an open PhD position to work on bacterial secretion systems. Please RT or apply through the CNRS job portal: emploi.cnrs.fr/Offres/Doctora…

@EzratyB @BIAM_CdE @lcb_officiel Exciting project ! Congratulations !

Thrilled to receive support from IM2B for an interdisciplinary project in collaboration with @BIAM_CdE , BIP and @lcb_officiel ; Il y a de l’hème dans l’air! 😃🔬🦠

@CunrathOlivier Félicitations Olivier !

I am happy to announce that I obtained my HDR (Habilitation à Diriger des Recherches) last Thursday. It has been a very nice exchange with the committee and we had some nice celebration afterwards 🍾