Connelly Lab

@sciqst Thanks for the comment and interest in our work. We foresee these types of models being used both for discovery of human-specific mechanisms of immune dysfunction in skin disease and for preclinical testing of drugs and immunotherapy.

Congratulations on your preprint publication! Modeling dynamic immune responses in human skin is a groundbreaking area with significant potential impacts on personalized medicine and dermatological treatments. How do you foresee these immuno-competent skin models influencing drug testing and development? Exciting times ahead for #Immunology and #BiomedicalResearch! Also, if you're looking to generate comprehensive reviews to complement your research findings, check out sciqst.com, a valuable tool for all your biomedical inquiries. #Medicine

We're pleased to share our new preprint on modelling dynamic immune responses in human skin! It has been a tremendous effort from everyone involved and we're excited to continue this new direction of research in immuno-competent skin models. biorxiv.org/content/10.110…

🚨 Super psyched this story is finally out!   Herculean effort and 3rd chef d’oeuvre in @NatCellBio by @patriziaromani in just 5y, where we describe #mitochondrial #mechanotransduction.   nature.com/articles/s4155…   Megathread with bonuses ⬇︎⬇︎⬇︎

Excited to share our new method in @ScienceMagazine to advance the properties of DLP-printed materials. This work was led by @apdhand & @fiber_matt in collaboration w/ @HannahZlotnick & NIST colleagues. Link: science.org/doi/10.1126/sc… @CUEngineering @pennbioeng @BioFrontiers

We are hiring for a postdoctoral scientist! Reposts appreciated

Pleased to share our new paper in @theJIDJournal on altered mechano-sensing in keloid fibroblasts and the impact on the lysosome! Fantastic work by @RosieRoss11 and @YiyangGuo2 in collaboration with @DrTJShaw. tinyurl.com/3d2v2fpu

Get your organ-on-a-chip abstracts in for #BioMedEng24, happening @QMUL this Sept! Slots for oral and poster presentations across two organ-on-a-chip (broadly defined) conference sessions. It’s going to be great! @OrganOnAChip @QMULCPM

Exciting news! The @QMULCPM has recently been awarded a large project grant from the EPSRC to develop new organ-on-chip technologies tinyurl.com/b9e3wstp. We are now recruiting for 3 postdoc positions!! tinyurl.com/ysvruxf5. Please get in touch in interested.

Enjoyed sharing our work on human skin models at the #EWMA2024 today! Lots of cool tech in the industry exhibition. @QMULCPM @QMCREATE

Prof Knight, Screen and Connelly will shortly be recruiting three new organ-chip post doctoral research assistants as part of a major 3-year grant on spatial tissue patterning within organ-chips funded by EPSRC with 6 industry partners, and based at Queen Mary @QMUL @QMULSciEng

Thoroughly enjoyed the @EMBOevents workshop on nuclear mechano-genomics this week! Great talks, discussion and location, and it was a pleasure to share our work on #mechanobiology of the nucleolus.

Huge news for #OrgandonChip research! @QMULSEMS awarded £7 million by @EPSRCCDT to train the next generation of scientists & bioengineers in this game-changing technology. This could revolutionise drug discovery & improve healthcare for all! #EPSRC_CDTs buff.ly/4cbF9TA

A heart-on-chip model from Julien Gautrot and @StefaniaDiCio @QMULSEMS captures functionality (beating) and the microvasculature of cardiac tissue. Explore how new approach methodologies can replace animals in drug/chemical safety testing on our NAMs hub: nc3rs.org.uk/3rs-resources/…

The GlycoWeb BBSRC sLOLA is recruiting! Please circulate to your networks and get in touch for more information. @2022Pg @GlycobiologyUK @ExtracellMatrix @SFGlycobiology @Glyco_Alps

Just a reminder I have a funded PhD advertised closing date is the 15th Feb.

Thank you George Eustice for visiting our Animal Replacement Centre of Excellence at @QMUL today to see first-hand human-specific research & meet with future-focused scientists. Great to discuss how #ethicalinnovation can boost our economy, our NHS, and advance medical research

New Year, new job? Excited to be #hiring a Deputy Manager for our Phenotypic Screening Facility #microscopy #multiplex #highcontent #drugdiscovery #screening Excellent training and development opportunity. Interested? Get in touch! Or share! 👉 lnkd.in/ePZy2_V9

Big lab news! The Herculean effort of Alice Scemama to understand cancer stem cell interaction with the vasculature in a microfluidic chip is now pre-printed. In her @NC3Rs PhD @blizard_inst @QMULBartsTheLon… 🧵

🤯 this is amazing! Engineered skin bacteria induce antitumor T cell responses against melanoma | Science science.org/doi/10.1126/sc…

We are expanding our programme offering next year to include an #MRes option for a more research focused degree. Come learn about stem cells, tissue engineering, and regeneration with us!