Dupree Lab

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Dupree Lab

Dupree Lab

@DupreeLab

The plant cell wall biology group of Paul Dupree in the @Cambridge_Uni

เข้าร่วม Eylül 2017
130 กำลังติดตาม628 ผู้ติดตาม
Dupree Lab
Dupree Lab@DupreeLab·
We are leaving X. Twitter has died. Please follow us on bluesky @dupreelab.bsky.social
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Dupree Lab
Dupree Lab@DupreeLab·
doi.org/10.1111/nph.20… Thanks @Jenny_Mortimer1 and Henrik Scheller for the insightful commentary on our recent work in @NewPhyt. We identified the missing ArapTs and GalTs for plant xylan synthesis. Bacteria may be adapting their GH30 xylanases to cleave these xylan structures!
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Dupree Lab
Dupree Lab@DupreeLab·
Congratulations to Wout and John! Their great research on plant cell walls, especially lignin synthesis and diversity of structure, is recognised with this prestigious prize
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Dupree Lab
Dupree Lab@DupreeLab·
Plant cell wall glycosyltransferases underpin the complex structure of dietary fibre. In our new work doi.org/10.1111/nph.19…, we show that β-xylosylated xyloglucan arose from the rapidly evolving GT47 family, while a promiscuous GH43 hydrolase permits its digestion in the gut.
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Dupree Lab
Dupree Lab@DupreeLab·
Wonderful news! We can’t wait to continue developing our plant cell wall architecture models using this amazing solid state NMR facility! #glycotime
Warwick Physics@WarwickPhysics

📢Prof. Steven Brown has been awarded £17M with consortium partners to procure the UK's most powerful Nuclear Magnetic Resonance (NMR) instrument at 1.2GHz. @NrfHf Funded by @EPSRC, the national facility will enable applications from batteries to pharmaceuticals. Find out more⬇️

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Dupree Lab
Dupree Lab@DupreeLab·
We are delighted to contribute to this opportunity to discover how plant cell walls can enable development of new sustainable materials #glycotime
Magda Titirici@titiricigroup

Is official: Thrilled to be the PI on a £6.1M @EPSRC programme grant to develop the next generation of sustainable material, both bio-based and bio-inspired! Can't wait to start working with an amazing team! @imperialcollege @BristolUni @Cambridge_Uni gow.epsrc.ukri.org/NGBOViewGrant.…

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Dupree Lab
Dupree Lab@DupreeLab·
Congratulations to @H_TempleS and @KI55141505 (Konan) for winning best postdoc talk and best PhD poster presentation at the IX Cell Wall Research Conference #glycotime
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Dupree Lab
Dupree Lab@DupreeLab·
Our work discovering putative Golgi SAM transporters is now out in @NaturePlants! rdcu.be/cPjUa Using solid state NMR with @MeiHongLab we found egg box pectin structures in the plant cell wall. Egg box formation is influenced by methylation status! #glycotime
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Dupree Lab รีทวีตแล้ว
Nature Plants
Nature Plants@NaturePlants·
New Article: "Golgi-localized putative S-adenosyl methionine transporters required for plant cell wall polysaccharide methylation" rdcu.be/cPkfB Methylation occurs in the Golgi and relies on the import of SAM molecules into the Golgi lumen by transporters.
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Dupree Lab
Dupree Lab@DupreeLab·
7/7 In plants, GT47 enzymes are vital for cell wall synthesis. Our phylogenies show that many non-angiosperms possess additional GT47s that are closely related to animal EXTs. However, the fusion with GT64 appears to have arisen only at the outset of metazoan evolution.
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Dupree Lab
Dupree Lab@DupreeLab·
6/7 Consistent with these features, and despite the presence of 10 mM UDP, we were unable to find density for UDP in the GT47 domain. The GT64 domain, however, binds UDP identically to murine EXTL2.
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Dupree Lab
Dupree Lab@DupreeLab·
We’re thrilled that our work on EXTL3 is finally out in @NatureComms! The structure is a first for Golgi bi-domain GTs and the GT47 family. There are discoveries on plant GT47s too: a putative UDP-binding motif and a new subclade in lower plants rdcu.be/cPfHm #glycotime
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