Joseph Hoock
11 posts
Joseph Hoock
@HoockJoseph
PhD student @ Laraia lab, DTU Chemistry Chemical biologist with interest in targeted protein degradation
Copenhagen, Denmark เข้าร่วม Mayıs 2021
111 กำลังติดตาม27 ผู้ติดตาม
@HoockJoseph @laraialab Congrats Joseph! Incredible achievement!
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I'm super happy and proud to share that today I won a prize for Best PhD in Medicinal Chemistry in Denmark. Grateful for my supervisor @laraialab and all collaborators I got to work with along the way. Excited to represent Denmark at the #EFMC-ISMC 2024 in Rome later this year.
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@laraialab Thank you Luca, your great supervision, guidance and believe in me enabled me to do this :)
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Massive congratulations to Dr @HoockJoseph for winning the best PhD thesis in med chem in Denmark! #proudPI
Joseph Hoock@HoockJoseph
I'm super happy and proud to share that today I won a prize for Best PhD in Medicinal Chemistry in Denmark. Grateful for my supervisor @laraialab and all collaborators I got to work with along the way. Excited to represent Denmark at the #EFMC-ISMC 2024 in Rome later this year.
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Huge congratulations to my colleague and good friend. Well deserved!
Joseph Hoock@HoockJoseph
I'm super happy and proud to share that today I won a prize for Best PhD in Medicinal Chemistry in Denmark. Grateful for my supervisor @laraialab and all collaborators I got to work with along the way. Excited to represent Denmark at the #EFMC-ISMC 2024 in Rome later this year.
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We were in fact able to show that a designated PROTAC led to specifc concentration dependent stabilisation, while the underlying small molecule KY02111 degraded our target squalene synthase. Enjoy the read!
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I'm excited that my project on degraders and stabilisers of SQS is out in Chemical Science as #ChemSciPicks. Gratefull for working with Cecilia, Mesut, @ERADLab, @Laura_dta and ofc @laraialab on this.
Luca Laraia@laraialab
Delighted that our paper on degraders and stabilisers of squalene synthase in @ChemicalScience has been highlighted as #chemscipicks! Fantastic work by @HoockJoseph with great support by Cecilia, Mesut, @ERADLab and @Laura_dta!
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Joseph Hoock รีทวีตแล้ว
📢New #PhDposition! Work with us @ChemistryDtu to develop tools for determining target engagement, selectivity and phenotypic effects of inhibitors of sterol transport proteins. Deadline: 27th July, but applications assessed continuously. Please RT efzu.fa.em2.oraclecloud.com/hcmUI/Candidat…
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My first preprint is out now! We targeted squalene synthase, an important enzyme for #cholesterol biosynthesis and identified small molecule degraders and stabilizers. Grateful for guidance by @laraialab 🙏 big thanks to Cecilia, @Laura_dta, @ERADLab and Mesut!
Luca Laraia@laraialab
New preprint! We discovered degraders and stabilizers of the #cholesterol biosynthesis enzyme squalene synthase, based on the same scaffold! Great work by PhD student @HoockJoseph, with support from Cecilia, @Laura_dta and collaborators Mesut and @ERADLab! biorxiv.org/content/10.110…
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