Dr. J.O
22.1K posts

Dr. J.O
@John0_
Husband. Christian. Internal Medicine Resident



One of the most amazing things I’ve ever seen: a standing ovation for the full Daraxonrasib results I feel inspired and energised, to put it mildly — we have a targeted therapy for pancreatic cancer now, and nothing is undruggable anymore



Today’s recommendation from the National Screening Committee on prostate cancer screening is deeply disappointing and a real step backwards. I urge the new Health Secretary to reject it and go further - offering targeted screening for the most at-risk men. As I warned last November following the initial advice, prostate cancer is the most common cancer among British men. We are letting down too many men, their families and loved-ones if we don’t push for a wider screening programme that includes all high-risk groups. Prostate cancer can be symptomless early on - as it was in my case. That’s why screening is essential - catching the cancers early when they can be more effectively and successfully treated, like with me. If the advice is to be followed, you could be an older, black man with a family history of prostate cancer and STILL not get routinely screened. Surely, that can’t be right? There are now better screening options and more advanced focused treatments available in parts of the NHS. I benefitted from these and others could too. Yet this seems to have been ignored by the Committee. The new Health Secretary needs to be brave and bold. A more progressive and life-saving policy is within our grasp. Put in place a proper, targeted screening programme that involves all those at higher-risk. Without it, more men will die, and more families will lose a loved-one. As I said in November, this is avoidable and can be done.




1/5 I'm a cardiologist. I have spent twenty years watching cholesterol destroy arteries, trigger heart attacks, and kill people I care about. Today, Eli Lilly presented data that may begin to end that era. VERVE-102. A single infusion. One dose. It uses base editing to permanently turn off the PCSK9 gene in your liver. Presented today at the European Atherosclerosis Society Congress: 88% reduction in PCSK9. 62% reduction in LDL cholesterol. Sustained up to 18 months. No treatment-related serious adverse events. One infusion. Not daily pills you forget to take. Not monthly injections. One dose — and your cholesterol may stay low for the rest of your life.










