Jacks Lab

We've moved!

@LCdr_mcgarrett This account is run by ill-informed lab members 😂 inquire with the link!

@LabJacks What is salary?

We're hiring technicians! Apply below. careers.peopleclick.com/careerscp/clie…

@Aamirsohailkt This account is run by ill-informed lab members 😂 inquire with the link

@LabJacks Are internationals eligible for tech positions?

Thanks to Tyler and Laura for hosting!

As the lab gets up and running following the break we'd like to share this picture from the annual holiday party. What a fun time!

The Lab Christmas tree is officially lit! Happy holidays to all :)

Excited to announce the Yang lab officially opens at @Columbia University. We are interested in developing innovative single cell recording technologies to study tumor evolution and cancer plasticity. We are hiring motivated postdocs & students, please RT dianyanglab.com

We were honored to be a part of the annual @lustgartenfdn walk this morning!

Out today, with @LabJacks, @isidrolauscher, @fran_muyas, we used new mouse models of spontaneous lung and colon cancer to delineate a mechanism for why many patients with DNA mismatch repair deficient (MMRd) tumors may not respond to immunotherapy 🧵1/11 nature.com/articles/s4158…

A heartfelt farewell to our amazing summer students Safya and Michelle! Congratulations on the amazing work and posters!

Our prime editor mouse is now available to request from The Jackson Laboratory: jax.org/strain/037953 jax.org/strain/037954

A prime editor mouse to model a broad spectrum of somatic mutations in vivo go.nature.com/3Bk8fz4

Many thanks to our awesome collaborators: @davidrliu, @fjsanchezrivera, and others!

Excited to share our new publication in @NatureBiotech nature.com/articles/s4158… Here, we introduce a genetically engineered mouse model that enables prime editing in vivo! We're excited about the system's potential for rapid and precise modeling of essentially any cancer mutation!

Tyler Jacks’ Keynote Lecture: “Genetic engineering meets tumor immunology: Lessons from mouse models of cancer” @LabJacks #eacrImmunoOncology

Tyler Jacks from @kochinstitute @MIT presenting eloquent vignettes (called tapas while @EACRnews #eacrImmunoOncology in Spain) on genetic engineering approaches in mice that have revealed profound insights into immuno-oncology and novel targets.

Ludwig @MIT Co-director Tyler Jacks spoke at #AACR2023 about the use of mouse models of cancer—further engineered to express cancer antigens or accumulate mutations in cancer cells—as a tool for nuanced and comprehensive study of anti-tumor immune responses.

Great to see our very own @KarenKarenoyee featured in @kochinstitute my voices! Thank you Karen for all you do!

We are currently hiring technicians! Apply if you're interested in 🐭 models of cancer, there are opportunities across cancer types and all of our research areas: careers.peopleclick.com/careerscp/clie…