ทวีตที่ปักหมุด
Excited to share our latest preprint on @biorxivpreprint: "The RBR E3 ubiquitin ligase HOIL-1 can ubiquitinate diverse non-protein substrates in vitro".
biorxiv.org/content/10.110…
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LechtenbergLab
310 posts
LechtenbergLab
@LechtenbergLab
News and updates from the Lechtenberg Lab at WEHI in Melbourne. Interested in Ubiquitin ligases, protein structures, and drug discovery. Views my own.
Melbourne, Victoria เข้าร่วม Eylül 2018
382 กำลังติดตาม766 ผู้ติดตาม
We are still accepting abstracts for selected short talks and posters. The abstract deadline has been extended to this Friday, 1st Aug. More information and registration here: lorneubiquitin.org .
LechtenbergLab@LechtenbergLab
📣📣 Lorne Ubiquitin – The Australian Ubiquitin Summit 📣📣 20-23 Nov 2025 in Lorne, Australia Join us this Nov for the first ubiquitin meeting in Australia. Submit your abstract by 18 July 2025 for oral and poster presentations: lorneubiquitin.org Please share and repost.
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📣📣 Lorne Ubiquitin – The Australian Ubiquitin Summit 📣📣
20-23 Nov 2025 in Lorne, Australia
Join us this Nov for the first ubiquitin meeting in Australia. Submit your abstract by 18 July 2025 for oral and poster presentations: lorneubiquitin.org
Please share and repost.
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LechtenbergLab รีทวีตแล้ว
Australia’s First Ubiquitin Summit is here! 🥳
📍Lorne, Victoria | 🗓️ 20–23 November 2025
Join us on the scenic coastline of Lorne for 4 days of cutting-edge ubiquitin science, featuring a fantastic lineup of international speakers covering all corners of the ubiquitin world
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LechtenbergLab รีทวีตแล้ว
Join us in Lorne for the 11th ISA. We have a fantastic line up of speakers at a beautiful coastal location in Australia. Hope to see you there!
Thanh (Ricky) Nguyen@ThanhNguyen_TNN
Michael Lazarou and I will be chairing the 11th International Symposium on Autophagy (ISA) in Australia from 16-20 Nov 2025! 📍 Location: Lorne, Victoria, Australia 🌐 Register now: isa11.org Join us for five inspiring days of cutting-edge autophagy research!
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We hope this will be useful for the field. A plasmid for expressing the constitutively active HOIL-1 variant is available via @Addgene: addgene.org/229539/
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Excited to share our latest work, now out in @LSAjournal. We show that the E3 ligase HOIL-1 can ubiquitinate many different saccharides and describe a chemoenzymatic platform to generate ubiquitinated sugars as tools for studying non-proteinaceous ubiquitination.
LifeScienceAlliance@LSAjournal
The RBR E3 ligase HOIL-1 ubiquitinates Ser/Thr-residues and various disaccharides in vitro and can be used to generate ubiquitinated sugars as tools to study non-proteinaceous ubiquitination @LechtenbergLab @WEHI_research life-science-alliance.org/content/8/6/e2…
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LechtenbergLab รีทวีตแล้ว
World-first: researchers have discovered what protein #PINK1 looks like in humans and how it is activated, solving a decades-long mystery in the fight against #Parkinsonsdisease. The team hope to use the knowledge to find a drug to stop #Parkinsons.
wehi.edu.au/news/scientist…
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Thrilled to be awarded an @nhmrc Investigator Grant for my research on “Advancing Proteolysis Targeting Chimera Molecular Design with Geometric Deep Learning”. Excited to continue AI-driven biological research at @SAiGENCI @UniofAdelaide!
NHMRC@nhmrc
229 of Australia’s brightest health and medical researchers will share in over $422 million under the 2025 round of NHMRC’s flagship scheme, Investigator Grants announced today by the Minister for Health and Aged Care, the Hon Mark Butler MP. Read more: ow.ly/pVQ750V50yq
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LechtenbergLab รีทวีตแล้ว
Super excited to be joining @RACInational for #MCCB2025 in Darwin #NT this April!!
#chembiol #drugdiscovery #peptides #ozchem
Royal Australian Chemical Institute@RACInational
Join keynote speakers Dr Pat Sharp, Dr Chiara Maniaci, Prof. Xin Zhang & Dr Madeline Kavanagh in Darwin (13-16 April) for insights into medicinal chemistry & chemical biology. 🔗 bit.ly/3PNkUl6 #MCCB2025 #MedChem #ChemBio #DrugDiscovery #NT
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LechtenbergLab รีทวีตแล้ว
Online Now: Combinatorial mapping of E3 ubiquitin ligases to their target substrates dlvr.it/THqW1q
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For those wanting to try to ubiquitinating sugars themselves: our plasmid for bacterial expression of the constitutive HOIL-1 variant is now available via Addgene: addgene.org/229539/
LechtenbergLab@LechtenbergLab
Excited to share our latest preprint on @biorxivpreprint: "The RBR E3 ubiquitin ligase HOIL-1 can ubiquitinate diverse non-protein substrates in vitro". biorxiv.org/content/10.110…
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LechtenbergLab รีทวีตแล้ว
I am looking for a research assistant to join my new lab in Melbourne, Australia at WEHI. Please apply at the link below!
tinyurl.com/4wkt2jve
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LechtenbergLab รีทวีตแล้ว
Just announced by WEHI, Sir Gus and the Nossal family: the Sir Gustav Nossal Professor of Immunology. This prestigious new position will lead pivotal research to advance human immunology. Made possible by a generous gift from the Nossal family.
Read more: wehi.edu.au/news/sir-gusta…
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Thanks to first author @xiangyi_susie, all members of my lab as well as collaborators and co-authors in the @komander_lab (@WEHI_research), @ethangbaus (WEHI) and @PayneResearch (@Sydney_Uni) labs.
biorxiv.org/content/10.110…
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We hope that our protocol will enable us and others to generate various ubiquitinated saccharides as tools to further develop the non-proteinaceous ubiquitin field. A plasmid for bacterial expression of the HOIL-1 variant will be available at @Addgene soon.
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Excited to share our latest preprint on @biorxivpreprint: "The RBR E3 ubiquitin ligase HOIL-1 can ubiquitinate diverse non-protein substrates in vitro".
biorxiv.org/content/10.110…
English
@WilflingLab @DGZ_info Well done, Konrad. Congratulations
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Brilliant news that our Masters student Konrad has been awarded the @DGZ_info Master Thesis Award! Very well deserved for his fantastic work during his time in the lab so far 🥳
DGZ, @DGZ.bsky.social@DGZ_info
Our very first @DGZ_info Master Thesis awards go to Florian Steinbach, @WilflingFlorian lab and Tamara Eleanore Hamann, @ZStorchova lab. Join us online for the 2024 @DGZ_info award ceremony on October 7th 12:30!
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