Julien Lefranc รีทวีตแล้ว
Julien Lefranc
932 posts
Julien Lefranc
@LefrancJu
#Medchem @merckgroup former @bayerpharma interested in #cancer #kinaseinhibitors #degraders only personal views Reviewer @drughunter
Darmstadt, Germany เข้าร่วม Kasım 2017
588 กำลังติดตาม905 ผู้ติดตาม
Congratulations to Chris, who defended his thesis and is now Dr. Cope, and to Dr. Huaquan Fang for Finishing up your research stay at our group. All the best to both of you!
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Julien Lefranc รีทวีตแล้ว
Molecule One-Pager: ARV-471 (vepdegestrant)
This molecule one-pager includes links to key presentations, publications, patents, preclinical and clinical PK data summaries, and more.
One-pager link: drughunters.com/3YoQR8v
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Julien Lefranc รีทวีตแล้ว
BMS-986365: A Next-Generation Oral AR Heterobifunctional Degrader for Drug-Resistant Prostate Cancer
This full case study details how BMS-986365 was engineered to have low intrinsic agonism and exert direct antagonism of WT AR and more!
Full Article: drughunters.com/4dIhx9d
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Julien Lefranc รีทวีตแล้ว
Événement : journée thématique de la #chimie accélérée et digitalisée en R&D le 19 septembre prochain à Paris Saclay! Au programme Laurence Grimaud (@ENS_ParisSaclay ) Pascal Mieville (@EPFL), Raphaël Steimbach (@Servier), Florian Médina (@JNJNews) et bien d’autres !
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Very nice to be back in Bristol for the CDT Summer Conference. A lot of great science presented by very talented PhD students ! Congratulations to @JonathanClayden, @VarinderAggar11 and @BCS_CDT
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Julien Lefranc รีทวีตแล้ว
If he could have dinner with a well-known historic figure, who would @AlexBismuto invite? @bismutolab @unibonn Find out on his #IntroducingAngewandte page twitter.com/16467437/statu… onlinelibrary.wiley.com/doi/10.1002/an…
Angewandte Chemie@angew_chem
Light-Dependent Reactivity of Heavy Pnictogen Double Bonds (Alessandro Bismuto and co-workers) @bismutolab #openaccess onlinelibrary.wiley.com/doi/10.1002/an…
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I keep being amazed by the work from @Rev_Medicine Here is a example from their last patent. This work is again pushing medicinal chemistry out of out comfort zone. 6 chiral centers, 1 atropisomer , a spiro and an aziridine ! Congratulations to @Les_Burnett and all the Team!
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Julien Lefranc รีทวีตแล้ว
There is still time to register for the Thematic meeting from @SCT_asso: Targeted Protein Degradation Gentilly @SanofiFR (Paris) with a fantastic program. You can click under the following link sct-asso.fr/tpdmeeting
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Congratulations to Mark for being one of the finalists at the Joint CDT Conference. Great presentation! @BristolChem @BCS_CDT
AggarwalLab@AggarwalLab
Congratulations to Mark Mandigma for being one of the finalists for best talk at the 4th Joint CDT Conference in Data Driven Chemical Synthesis and Catalysis, where he presented his work on enantiospecific cross coupling of heterocycles with alkyl boronic esters.
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Julien Lefranc รีทวีตแล้ว
Julien Lefranc รีทวีตแล้ว
🔥🔥“TPD one-day Thematic meeting” in Paris (SANOFI) May 30th 2024 @SCT_asso : register open bit.ly/4arCfZd
@DanNomura
Dr. M. Schroeder
@fmorreale_ester
Prof. N. Thomä
@iDikic2
Dr. M. Koegl
Dr. S. Jegham
Dr. K. McAulay
Prof. A.-S. Voisin-Chiret
Julien Lefranc รีทวีตแล้ว
Molecules of the Month – Feb. 2024
Actelion revealed the discovery story of nivasorexant, a selective orexin-1 receptor antagonist, which completed a Ph. II clinical trial in binge-eating disorder.
Check out our other top molecules from Feb.!
Article | drughunters.com/3vbzEDY
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Julien Lefranc รีทวีตแล้ว
We have an open position for a postdoc in our Medicinal Chemistry & Drug Design department @merckgroup: If you are equally excited about chemistry automation and about applying synthetic chemistry to answer biological questions, check out this highly attractive opportunity!
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