Mahmoud ShaMs, MD

We are deeply saddened to have lost our founding chairman and the father of modern academic cardiology, Dr. Eugene Braunwald, who founded the TIMI Study Group in 1984, and with that vision profoundly shaped the practice of cardiovascular medicine across the world.

It was a privilege to know Dr Braunwald for several decades . We collaborated on dozens of HF trials , from the planning and implementation of the NHLBI HF network, the STICH trial, and others. He was always generous with his time whether writing a letter of congratulations or offering thoughtful advice with a simple call. Despite his unmatched leadership and contributions to cardiovascular knowledge , research, and education, he often said his greatest joy was mentoring the hundreds of individuals he influenced directly and indirectly. Truly the GOAT ( greatest of all time ) in our generation. Later in life , he said Chris, you can call me Gene; I replied thank you Dr. Braunwald. Rest in peace, Dr Braunwald. We will miss you . Chris

The American Heart Association mourns the passing of the legendary cardiologist Eugene Braunwald, M.D., widely recognized as one of the most influential figures in the history of cardiovascular medicine. Over seven decades, his work reshaped the understanding and treatment of heart disease, leading many to call him the father of modern cardiology. Braunwald was a lifelong contributor to the American Heart Association, helping advance its research and scientific mission, and was honored with some of the Association’s highest honors for his lasting influence on cardiovascular care and research. His influence extended well beyond his own discoveries, as generations of Association‑supported investigators, clinicians and academic leaders were trained by Braunwald or guided by the clinical trial standards and mentorship models he helped establish. newsroom.heart.org/news/american-…

With a very heavy heart, we say goodbye to Dr. Eugene Braunwald, a true legend, a wise leader, and caring mentor who shaped the field of cardiology and will continue to influence it for generations. I was blessed to have worked with him and learned directly from him. R.I.P EP

📣 We’re hiring! The Lau Women’s Heart Lab at @MassGenBrigham is looking for a MD research fellow (patient-oriented 🫀research, epi) to join our team! Apply here tinyurl.com/3eb8byes or reach out to elau6@mgb.org to learn more.

@drnourzalat طالما فيه other programs مهتمه بال MS degrees فدا بيقوي الموقف. هي الفكره كلها اننا محتاجين نفهم ال top tier بيختاروا وبيفكروا ازاي وبناءا علي ايه من ناس متشت فعلا عندهم مش بس علي حسب فهمنا عشان نعرف نخش وسطهم زي اللبنانيين ودي نصيحتي لاي حد لسه في الكليه انه يهتم بدرجاته

@ShaMss73 مش شرط خالص خالص، عادي كونراد فيشر انترستد في الmed school degree والبروجرام مش توب تير، على حسب الleadership وحاجات كتير تانية

Guys you need to know that medical school degrees matter for high tier programs

After a certain age, your parents slowly become your children. They ask simple questions, repeat stories, and depend on your patience the way you once depended on theirs. Very few understand this role reversal.What looks like innocence or inconvenience is really time coming full circle. Don't correct them harshly. Don't rush them. Care for them the way they once protected you. This is not a burden. It is repayment.

@aklfahed @NatureComms That’s impressive work, congrats 👏

New from our group published in @NatureComms nature.com/articles/s4146… What is the maximal information you can get from a single DNA sample to predict heart attack risk? We developed an integrated genomic model that combines germline (polygenic risk scores, monogenic variants) and somatic (CHIP, LTL) information. Risk is demonstrated as a gradient on a 2D envelope capturing germline and somatic risk. We identify ~ 13% of high-risk individuals who would have been missed by polygenic risk score alone. Wonderful collaboration co-led with @pnatarajanmd and @wallacemwang Thread form postdoc extraordinaire and co-first author @MinSeoKim_MD in comments @MGBResearchNews @broadinstitute

Lower LDL earlier in the disease process with PCSK9i Subgroup analysis form VESALIUS-CV #ACC26 Congrats @marstonMD and team jamanetwork.com/journals/jama/…

@MohamedA_AliH شكرا جدا يامحمد علي الكلام الجميل دا ربنا يكرمك ويوفقك يارب والجميع ان شاء الله🙏🙏

بخصوص الResearch positions دي حلقة لدكتور محمود مع ASSA-ASSIUT youtu.be/3vqhU9gLNgk?si… اتكلم عنها... الحلقة مفيدة جدا بصراحة شكرا لدكتور محمود و ASSA-ASSIUT.

@khyatovic انت اخويا المحترم الغالي ابن الاصول 😘

ديه اعظم حلقة اتعملت عن الموضوع ده علشان محمود اخويا شمس طبعا اللي عاملها ❤️ @ShaMss73

Feeling very excited and grateful to be joining @OBHBrookdaleIM for Internal Medicine! Looking forward to training under the leadership of Doctor @SeeFisch , learning from an incredible team, and staying in Brooklyn for the next 3 years! 🥳🤩

💬 Viewpoint: The widespread use of #AI for residency application screening in US graduate medical education programs introduces new legal and ethical concerns, particularly regarding disparate impact discrimination and unvalidated subgroup performance. ja.ma/4sokaEO

Among patients with atrial fibrillation at high risk for stroke and bleeding, left atrial appendage closure was not noninferior to medical therapy in reducing the risk of stroke, embolism, major bleeding, or death at 3 years. Full CLOSURE-AF trial results: nejm.org/doi/full/10.10… Editorial: Left Atrial Appendage Closure — Another Overused Method in Cardiology? nejm.org/doi/full/10.10…

@SaraHelmy00 Huge congratulations ya sara mashallah alf alf mabroook

Alhamdulillah Matched into IM! 🥹 اللهم لك الحمد حمدًا كثيرًا طيّبًا مباركًا فيه

One Size Does Not Fit All: Optimizing anticoagulant dose selection using sophisticated machine learning and incorporation of patient preferences - an analysis from #ENGAGE AF-TIMI 48 @rgiugliano sciencedirect.com/science/articl…

A nature study found that “ChatGPT Health”failed to direct users to emergency care in >50% of serious clinical scenarios & showed inconsistent suicide‑crisis alerts. This is very dangerous and raises a big safety concern theguardian.com/technology/202… nature.com/articles/s4159

@khyatovic اسطووووورتنا❤️❤️

غفلناهم تاني اللهم لك الحمد حمدا كثيرا طيبا مباركا فيه ❤️

#RotatorCuff abnormalities on #MRI were found in 99% of adults aged 41–76, including 96% of asymptomatic shoulders, indicating most findings are age-related rather than disease. ja.ma/4qD96Su